Pathogenesis of bone lesions in rheumatoid arthritis

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Pathogenesis of bone lesions in rheumatoid arthritis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1019883328
P356DOI10.1007/S11926-002-0069-Y
P698PubMed publication ID12010607

P50authorSteven R GoldringQ114399448
Ellen M GravalleseQ117258216
P2860cites workOsteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cellsQ24315251
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesisQ24563235
RANK is essential for osteoclast and lymph node developmentQ24598872
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokinesQ24678115
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritisQ24796707
A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesisQ28255805
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Cysteine proteinase cathepsin K mRNA is expressed in synovium of patients with rheumatoid arthritis and is detected at sites of synovial bone destruction.Q31996316
Intranasal calcitonin for the prevention of bone erosion and bone loss in rheumatoid arthritisQ33564710
Bone resorption by cells isolated from rheumatoid synoviumQ33584114
The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.Q33823576
The role of cytokines in the pathogenesis of rheumatoid arthritisQ33823954
From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulinsQ33860728
Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study GroupQ33885648
Cellular mechanisms and the role of cytokines in bone erosions in rheumatoid arthritisQ34064293
The human osteoclast precursor circulates in the monocyte fractionQ34392302
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.Q34469691
Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradationQ35747144
Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritisQ35764588
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritisQ35788463
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient miceQ36791739
Synovium as a source of increased amino-terminal parathyroid hormone-related protein expression in rheumatoid arthritis. A possible role for locally produced parathyroid hormone-related protein in the pathogenesis of rheumatoid arthritisQ37380147
Factors predicting outcome of rheumatoid arthritis: results of a followup studyQ41072217
Cytokines in the pathogenesis of osteoporosisQ41736045
Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerinQ43937881
The erosive front: a topographic study of the junction between the pannus and the subchondral plate in the macerated rheumatoid metacarpal headQ44063757
Osteoclast-like cells in murine collagen induced arthritisQ47957228
The progression of erosion and joint space narrowing scores in rheumatoid arthritis during the first twenty-five years of disease.Q50550086
Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist.Q50850177
Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial.Q52221782
IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation.Q53775252
Osteoclast-like cells in an in vitro model of bone destruction by rheumatoid synovium.Q54003767
Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint.Q54003771
Induction of abundant osteoclast-like multinucleated giant cells in adjuvant arthritic rats with accompanying disordered high bone turnover.Q54129470
Generation of osteoclastic function in mouse bone marrow cultures: multinuclearity and tartrate-resistant acid phosphatase are unreliable markers for osteoclastic differentiation.Q54355784
The relationship between synovitis and bone changes in early untreated rheumatoid arthritis: A controlled magnetic resonance imaging studyQ56420842
Interleukin 15: a proinflammatory role in rheumatoid arthritis synovitisQ57232104
Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritisQ57232110
T Cell Activation Induces Human Osteoclast Formation via Receptor Activator of Nuclear Factor κB Ligand-Dependent and -Independent MechanismsQ60524745
Effect of calcitonin on bone histomorphometry and bone metabolism in rheumatoid arthritisQ67753616
NE-58095: a diphosphonate which prevents bone erosion and preserves joint architecture in experimental arthritisQ69277665
Failure of cells of the mononuclear phagocyte series to resorb boneQ70515523
Histopathology of the rheumatoid lesion. Identification of cell types at sites of cartilage erosionQ70580984
Increased bone mass with pamidronate treatment in rheumatoid arthritis. Results of a three-year randomized, double-blind trialQ71016803
Bone resorption by tartrate-resistant acid phosphatase-positive multinuclear cells isolated from rheumatoid synoviumQ71055741
Organ-specific disease provoked by systemic autoimmunityQ71838378
Parathyroid hormone-related peptide in synovial fluid and disease activity of rheumatoid arthritisQ71843610
Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid jointQ72824611
Activated T lymphocytes support osteoclast formation in vitroQ73149439
Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators GroupQ73207664
Arthritis provoked by linked T and B cell recognition of a glycolytic enzymeQ73216181
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factorQ73490934
Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritisQ73490940
Expression of osteoclast differentiation factor at sites of bone erosion in collagen-induced arthritisQ73678529
Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patientsQ73880310
Zoledronate (CGP 42'446), a bisphosphonate, protects against metaphyseal intracortical defects in experimental inflammatory arthritisQ74300801
A novel role of IL-15 in the development of osteoclasts: inability to replace its activity with IL-2Q74595874
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synoviumQ77738643
P433issue3
P921main subjectrheumatoid arthritisQ187255
P304page(s)226-231
P577publication date2002-06-01
P1433published inCurrent Rheumatology ReportsQ23930052
P1476titlePathogenesis of bone lesions in rheumatoid arthritis
P478volume4

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cites work (P2860)
Q92659462"It's my own fault": Accounts and consequences of falling when living with rheumatoid arthritis
Q54188388Association of toll-like receptor 4 signaling pathway with steroid-induced femoral head osteonecrosis in rats.
Q35620364Early changes in bone mineral density measured by digital X-ray radiogrammetry predict up to 20 years radiological outcome in rheumatoid arthritis
Q36245404Effects of Antitumor Necrosis Factor Therapy on Osteoprotegerin, Neopterin, and sRANKL Concentrations in Patients with Rheumatoid Arthritis.
Q37140765Etanercept Promotes Bone Formation via Suppression of Dickkopf-1 Expression in Rats with Collagen-Induced Arthritis.
Q40643961Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis
Q37524529Immune response associated with Toll-like receptor 4 signaling pathway leads to steroid-induced femoral head osteonecrosis
Q36618009Mechanisms of bone loss in rheumatoid arthritis
Q37812618Microarchitectural adaptations in aging and osteoarthrotic subchondral bone issues.
Q35086184Quantifying not only bone loss, but also soft tissue swelling, in a murine inflammatory arthritis model using micro-computed tomography
Q28570898RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies
Q36860987Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease.
Q79808629Regulation of bone lysis in inflammatory diseases
Q35554105T cells, fibroblast-like synoviocytes, and granzyme B+ cytotoxic cells are associated with joint damage in patients with recent onset rheumatoid arthritis
Q36536886TNFalpha blockade in human diseases: mechanisms and future directions
Q34734335Tumor necrosis factor-α signaling in macrophages.

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