Metabolic engineering of microorganisms for the production of L-arginine and its derivatives

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Metabolic engineering of microorganisms for the production of L-arginine and its derivatives is …
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review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1044915995
P356DOI10.1186/S12934-014-0166-4
P2888exact matchhttps://scigraph.springernature.com/pub.10.1186/s12934-014-0166-4
P932PMC publication ID4258820
P698PubMed publication ID25467280
P5875ResearchGate publication ID269172982

P50authorSang Yup LeeQ30506231
Jae Ho ShinQ57051316
P2093author name stringJae Ho Shin
P2860cites workBiosynthesis and metabolism of arginine in bacteriaQ24634435
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Identification and elimination of the competing N-acetyldiaminopentane pathway for improved production of diaminopentane by Corynebacterium glutamicumQ28749947
Interaction of transcriptional repressor ArgR with transcriptional regulator FarR at the argB promoter region in Corynebacterium glutamicumQ29346527
A novel type of N-acetylglutamate synthase is involved in the first step of arginine biosynthesis in Corynebacterium glutamicumQ30679869
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The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitaminsQ33968067
Biotechnological production of amino acids and derivatives: current status and prospectsQ33990399
Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiberQ34069650
Plasmid addiction systems: perspectives and applications in biotechnologyQ34160193
Bio-based production of chemicals, materials and fuels -Corynebacterium glutamicum as versatile cell factoryQ34237887
Primary structure, partial purification and regulation of key enzymes of the acetyl cycle of arginine biosynthesis in Bacillus stearothermophilus: dual function of ornithine acetyltransferase.Q34363390
Metabolic engineering of Escherichia coli using synthetic small regulatory RNAsQ34555151
Improvement of L-arginine production by overexpression of a bifunctional ornithine acetyltransferase in Corynebacterium crenatum.Q54356482
Production of the amino acids l-glutamate, l-lysine, l-ornithine and l-arginine from arabinose by recombinant Corynebacterium glutamicum.Q54382454
From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine productionQ57988563
Metabolic engineering of Escherichia coli for the production of cadaverine: A five carbon diamineQ61447361
Canavanine and homoarginine as antimetabolites of arginine and lysine in yeast and algaeQ73723575
L-arginine stimulation of glucose-induced insulin secretion through membrane depolarization and independent of nitric oxideQ74484522
Heterologous expression of cyanophycin synthetase and cyanophycin synthesis in the industrial relevant bacteria Corynebacterium glutamicum and Ralstonia eutropha and in Pseudomonas putidaQ77451033
Feedback inhibition of acetylglutamate synthetase by arginine in Escherichia coliQ79702306
Site-directed mutagenesis studies on the L-arginine-binding sites of feedback inhibition in N-acetyl-L-glutamate kinase (NAGK) from Corynebacterium glutamicumQ82600274
Implication of gluconate kinase activity in L-ornithine biosynthesis in Corynebacterium glutamicumQ84985127
Enhanced production of L-arginine by expression of Vitreoscilla hemoglobin using a novel expression system in Corynebacterium crenatumQ85019811
Metabolic engineering of Corynebacterium glutamicum for L-arginine productionQ47989578
The Bacillus stearothermophilus argCJBD operon harbours a strong promoter as evaluated in Escherichia coli cells.Q48015574
Arginine boxes and the argR gene in Streptomyces clavuligerus: evidence for a clear regulation of the arginine pathwayQ48047531
Genes and enzymes of the acetyl cycle of arginine biosynthesis in Corynebacterium glutamicum: enzyme evolution in the early steps of the arginine pathway.Q48067885
Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginineQ48405578
Arginine enhances wound healing and lymphocyte immune responses in humans.Q51729082
Metabolic engineering of Corynebacterium glutamicum for increasing the production of L-ornithine by increasing NADPH availability.Q51799187
A novel plasmid addiction system for large-scale production of cyanophycin in Escherichia coli using mineral salts medium.Q52297384
Physiological conditions conducive to high cell density and high cyanophycin content in Ralstonia eutropha strain H16 possessing a KDPG aldolase gene-dependent addiction system.Q52299763
Improving putrescine production by Corynebacterium glutamicum by fine-tuning ornithine transcarbamoylase activity using a plasmid addiction system.Q52300400
Metabolic engineering of Corynebacterium glutamicum for the production of L-ornithine.Q53463146
Plasma levels of prolactin, growth hormone and insulin in sheep following the infusion of arginine, leucine and phenylalanine.Q54023096
N-Acetylglutamate Synthetase of Pseudomonas aeruginosa. An Assay in vitro and Feedback Inhibition by ArginineQ54272876
Metabolic engineering of Escherichia coli for the production of 5-aminovalerate and glutarate as C5 platform chemicals.Q54320986
Heterologous and homologous expression of the arginine biosynthetic argC~H cluster from Corynebacterium crenatum for improvement of (L) -arginine production.Q54350526
Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretionQ34560718
Metabolic evolution of Corynebacterium glutamicum for increased production of L-ornithineQ34750524
Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymersQ35014483
Cloning and organization of seven arginine biosynthesis genes from Neisseria gonorrhoeaeQ35189146
Surprising arginine biosynthesis: a reappraisal of the enzymology and evolution of the pathway in microorganismsQ35740868
Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulationQ35762068
Metabolic engineering of Clostridium acetobutylicum ATCC 824 for isopropanol-butanol-ethanol fermentationQ35804845
Arginine-stimulated acute phase of insulin and glucagon secretion in diabetic subjectsQ35903867
Sequence analysis and complementation studies of the argJ gene encoding ornithine acetyltransferase from Neisseria gonorrhoeaeQ36111080
Systems metabolic engineering of Escherichia coli for L-threonine productionQ36327201
Pathways and regulation of bacterial arginine metabolism and perspectives for obtaining arginine overproducing strainsQ36376054
Cloning and expression in Escherichia coli of a Streptomyces coelicolor A3(2) argCJB gene clusterQ36749790
Systems and synthetic metabolic engineering for amino acid production - the heartbeat of industrial strain developmentQ37975758
Bio-based production of C2-C6 platform chemicalsQ38024271
FarR, a putative regulator of amino acid metabolism in Corynebacterium glutamicum.Q38302035
Arginine regulon of Escherichia coli K-12. A study of repressor-operator interactions and of in vitro binding affinities versus in vivo repressionQ38327423
Technical-scale production of cyanophycin with recombinant strains of Escherichia coliQ39650124
Arginine biosynthesis and regulation in Lactobacillus plantarum: the carA gene and the argCJBDF cluster are divergently transcribedQ39845380
Increase in arginine and citrulline production by 6-azauracil-resistant mutants of Bacillus subtilisQ40074699
Pathway-Specific Pattern of Control of Arginine Biosynthesis in BacteriaQ40434782
The regulatory region of the divergent argECBH operon in Escherichia coli K-12.Q40497721
Production of l -Arginine by Arginine Hydroxamate-Resistant Mutants of Bacillus subtilisQ40711601
Physiological conditions conducive to high cyanophycin content in biomass of Acinetobacter calcoaceticus strain ADP1.Q40984541
Autotrophic production of stable-isotope-labeled arginine in Ralstonia eutropha strain H16.Q41587632
Engineering the genotype of Acinetobacter sp. strain ADP1 to enhance biosynthesis of cyanophycinQ41880209
Dietary L-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese ratsQ41890184
Reengineering of a Corynebacterium glutamicum L-arginine and L-citrulline producerQ42121269
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediolQ42733691
Putrescine production by engineered Corynebacterium glutamicumQ42956922
Identification of a suppressor gene for the arginine-auxotrophic argJ mutation in Corynebacterium glutamicumQ43026749
Characterization and kinetic mechanism of mono- and bifunctional ornithine acetyltransferases from thermophilic microorganisms.Q43027812
Engineering of sugar metabolism of Corynebacterium glutamicum for production of amino acid L-alanine under oxygen deprivationQ43136250
Enhancement of ornithine production in proline-supplemented Corynebacterium glutamicum by ornithine cyclodeaminase.Q43172403
Proline reduces the binding of transcriptional regulator ArgR to upstream of argB in Corynebacterium glutamicum.Q43268221
Metabolic engineering of Escherichia coli for the production of putrescine: a four carbon diamineQ43284345
Safety and efficacy of LK565--a new polymer ultrasound contrast mediumQ43696381
Purification and characterization of an arginine regulatory protein, ArgR, in Corynebacterium glutamicumQ43929871
Effect of arginine, ornithine and citrulline supplementation upon performance and metabolism of trained ratsQ44310392
Metabolic engineering of Clostridium acetobutylicum for the enhanced production of isopropanol-butanol-ethanol fuel mixture.Q45915647
Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology.Q45950746
Crude glycerol-based production of amino acids and putrescine by Corynebacterium glutamicum.Q45969285
Effect of increased glutamate availability on L-ornithine production in Corynebacterium glutamicum.Q46519619
Application of a KDPG-aldolase gene-dependent addiction system for enhanced production of cyanophycin in Ralstonia eutropha strain H16.Q46788197
Structural bases of feed-back control of arginine biosynthesis, revealed by the structures of two hexameric N-acetylglutamate kinases, from Thermotoga maritima and Pseudomonas aeruginosaQ46867445
Identification of the Anabaena sp. strain PCC7120 cyanophycin synthetase as suitable enzyme for production of cyanophycin in gram-negative bacteria like Pseudomonas putida and Ralstonia eutrophaQ47222185
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)166
P577publication date2014-12-03
P1433published inMicrobial Cell FactoriesQ15766995
P1476titleMetabolic engineering of microorganisms for the production of L-arginine and its derivatives
P478volume13

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cites work (P2860)
Q64935181Biological conversion of methane to putrescine using genome-scale model-guided metabolic engineering of a methanotrophic bacterium Methylomicrobium alcaliphilum 20Z.
Q42467161Effect of Tween 40 and DtsR1 on L-arginine overproduction in Corynebacterium crenatum
Q52649022Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine.
Q90094325Improvement of l-arginine production by in silico genome-scale metabolic network model guided genetic engineering
Q48858150Improvement of the ammonia assimilation for enhancing L-arginine production of Corynebacterium crenatum.
Q46508496Improvement of the intracellular environment for enhancing l-arginine production of Corynebacterium glutamicum by inactivation of H2O2-forming flavin reductases and optimization of ATP supply
Q42231384Metabolic engineering of Escherichia coli for enhanced arginine biosynthesis
Q40894747Metabolic pathway engineering using the central signal processor PII.
Q89785842Our microbes not only produce antibiotics, they also overproduce amino acids
Q48891833Reengineering of the feedback-inhibition enzyme N-acetyl-L-glutamate kinase to enhance L-arginine production in Corynebacterium crenatum.
Q37034851Systems pathway engineering of Corynebacterium crenatum for improved L-arginine production

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