| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | David G Warnock | |
| Ji-Bin Peng | |||
| P2860 | cites work | CFTR is a conductance regulator as well as a chloride channel | Q47606637 |
| Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments | Q47937701 | ||
| Molecular identification of the apical Ca2+ channel in 1, 25-dihydroxyvitamin D3-responsive epithelia | Q47978841 | ||
| Novel subunit composition of a renal epithelial KATP channel | Q48034777 | ||
| The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1. | Q48845938 | ||
| WNK1 and WNK4 modulate CFTR activity. | Q50640928 | ||
| WNK4 kinase is a negative regulator of K+-Cl- cotransporters. | Q50641258 | ||
| Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo. | Q50646202 | ||
| Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved. | Q50647853 | ||
| Apical localization of renal K channel was not altered in mutant WNK4 transgenic mice. | Q50662034 | ||
| Developmental regulation of CFTR expression during human nephrogenesis. | Q52200150 | ||
| Cystic fibrosis transmembrane conductance regulator in the kidney: clues to its role? | Q53926763 | ||
| Mineralocorticoid-resistant renal hyperkalemia without salt wasting (type II pseudohypoaldosteronism): role of increased renal chloride reabsorption. | Q54535930 | ||
| OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity | Q24290380 | ||
| WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis | Q24294248 | ||
| WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding | Q24302525 | ||
| Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter | Q24311551 | ||
| Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression | Q24534668 | ||
| Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms | Q24537454 | ||
| Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4 | Q24541348 | ||
| Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1 | Q24548301 | ||
| Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5 | Q24617659 | ||
| WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia | Q24621479 | ||
| Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform | Q24633475 | ||
| Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins | Q24633640 | ||
| Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor | Q24647926 | ||
| An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis | Q24669948 | ||
| WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells | Q24676697 | ||
| Intersectin links WNK kinases to endocytosis of ROMK1 | Q24680263 | ||
| CFTR expression in cortical collecting duct cells | Q41250423 | ||
| CFTR as a cAMP-dependent regulator of sodium channels | Q41312779 | ||
| CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney | Q42018121 | ||
| Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4. | Q42479166 | ||
| Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel | Q43982359 | ||
| Pseudohypoaldosteronism type II: marked sensitivity to thiazides, hypercalciuria, normomagnesemia, and low bone mineral density | Q44055170 | ||
| WNK1, a Gene within a Novel Blood Pressure Control Pathway, Tissue-Specifically Generates Radically Different Isoforms with and without a Kinase Domain | Q44599907 | ||
| Role of Na+/Ca2+ exchange in regulating cytosolic Ca2+ in cultured human pulmonary artery smooth muscle cells. | Q45983075 | ||
| WNK4 regulates airway Na+ transport: study of familial hyperkalaemia and hypertension | Q46539148 | ||
| A new kindred with pseudohypoaldosteronism type II and a novel mutation (564D>H) in the acidic motif of the WNK4 gene | Q46585008 | ||
| Hypokalemia in a mouse model of Gitelman's syndrome | Q46910086 | ||
| Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption | Q28140902 | ||
| WNK kinases, a novel protein kinase subfamily in multi-cellular organisms | Q28188729 | ||
| Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A | Q28189806 | ||
| Human hypertension caused by mutations in WNK kinases | Q28212182 | ||
| Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel | Q28240272 | ||
| Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits | Q28249570 | ||
| WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron | Q28250388 | ||
| The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion | Q28255750 | ||
| Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome | Q28288744 | ||
| WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension | Q28305389 | ||
| Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells | Q28505442 | ||
| WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion | Q28506376 | ||
| A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel | Q28512481 | ||
| Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene | Q28513722 | ||
| Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform | Q28567514 | ||
| WNK1 affects surface expression of the ROMK potassium channel independent of WNK4 | Q28571983 | ||
| WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II | Q28581920 | ||
| The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases | Q28583124 | ||
| WNK kinases regulate thiazide-sensitive Na-Cl cotransport | Q28584824 | ||
| Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention | Q28591574 | ||
| Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1) | Q28593751 | ||
| Structural conservation of the genes encoding CaT1, CaT2, and related cation channels | Q30713630 | ||
| Role of with-no-lysine [K] kinases in the pathogenesis of Gordon's syndrome. | Q31039816 | ||
| Genome-wide detection of tissue-specific alternative splicing in the human transcriptome | Q31106050 | ||
| Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2. | Q31845574 | ||
| Molecular mechanisms of human hypertension | Q32138445 | ||
| Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport | Q33736529 | ||
| Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia | Q33775321 | ||
| Mammalian distal tubule: physiology, pathophysiology, and molecular anatomy | Q33807213 | ||
| WNK1 activates SGK1 to regulate the epithelial sodium channel. | Q33900653 | ||
| Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4. | Q34125574 | ||
| WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability. | Q34133418 | ||
| Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human | Q34181852 | ||
| Genetic variants of WNK4 in whites and African Americans with hypertension | Q34193390 | ||
| Genetic forms of human hypertension | Q34310450 | ||
| Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3). | Q34326671 | ||
| Hypercalciuria in familial hyperkalemia and hypertension accompanies hyperkalemia and precedes hypertension: description of a large family with the Q565E WNK4 mutation | Q34338478 | ||
| Mitogenesis and endocytosis: What's at the INTERSECTIoN? | Q34405524 | ||
| WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. | Q34464530 | ||
| WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia | Q34470465 | ||
| WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway | Q34478816 | ||
| WNK kinases influence TRPV4 channel function and localization | Q34483111 | ||
| WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells | Q34524228 | ||
| WNK4 enhances TRPV5-mediated calcium transport: potential role in hypercalciuria of familial hyperkalemic hypertension caused by gene mutation of WNK4. | Q34571331 | ||
| WNK1 kinase isoform switch regulates renal potassium excretion. | Q34694518 | ||
| Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport | Q34777003 | ||
| WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo. | Q35651892 | ||
| WNK kinases: molecular regulators of integrated epithelial ion transport | Q35858400 | ||
| Sodium and potassium handling by the aldosterone-sensitive distal nephron: the pivotal role of the distal and connecting tubule | Q35877684 | ||
| Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters. | Q36079002 | ||
| Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch | Q36088720 | ||
| WNK kinases and the control of blood pressure | Q36113496 | ||
| TRPV4 and the mammalian kidney | Q36179340 | ||
| Familial hyperkalemic hypertension | Q36284783 | ||
| SPAK and OSR1, key kinases involved in the regulation of chloride transport | Q36492481 | ||
| WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters | Q36600738 | ||
| Type 2 pseudohypoaldosteronism: new insights into renal potassium, sodium, and chloride handling | Q36601867 | ||
| Life and death of the distal nephron: WNK4 and NCC as major players | Q36644717 | ||
| Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension | Q37571326 | ||
| Immunocytochemical localization of the cystic fibrosis gene product CFTR | Q37609030 | ||
| The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport | Q37714173 | ||
| Identification of 108 SNPs in TSC, WNK1, and WNK4 and their association with hypertension in a Japanese general population | Q38337767 | ||
| Study of claudin function by RNA interference | Q40224183 | ||
| Overexpression of human WNK1 increases paracellular chloride permeability and phosphorylation of claudin-4 in MDCKII cells | Q40237008 | ||
| WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1). | Q40339717 | ||
| WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism | Q40388688 | ||
| Properties of WNK1 and implications for other family members | Q40424747 | ||
| Regulation of apical localization of the thiazide-sensitive NaCl cotransporter by WNK4 in polarized epithelial cells | Q40441541 | ||
| Evidence for endocytosis of ROMK potassium channel via clathrin-coated vesicles | Q40705695 | ||
| Trp12, a novel Trp related protein from kidney | Q40840056 | ||
| P433 | issue | 4 | |
| P304 | page(s) | F961-73 | |
| P577 | publication date | 2007-07-18 | |
| P1433 | published in | American Journal of Physiology - Renal Physiology | Q2610177 |
| P1476 | title | WNK4-mediated regulation of renal ion transport proteins | |
| P478 | volume | 293 |
| Q41857194 | Analysis and update of the human solute carrier (SLC) gene superfamily |
| Q34156696 | Concerted actions of NHERF2 and WNK4 in regulating TRPV5 |
| Q35774063 | Perspective of future drugs targeting sterile 20/SPS1-related proline/alanine-rich kinase for blood pressure control |
| Q35976038 | Renal adaptation to gentamicin-induced mineral loss |
| Q24646108 | WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter |
| Q37025005 | WNK4 inhibits Ca(2+)-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathway |
| Q36943378 | WNK4 regulates the secretory pathway via which TRPV5 is targeted to the plasma membrane |
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