scholarly article | Q13442814 |
P2093 | author name string | Xiao-Jing Wang | |
Peter Andersen | |||
Christopher L Corless | |||
Shi-Long Lu | |||
Sophia Bornstein | |||
Stephen Weber | |||
Heather Herrington | |||
Douglas Reh | |||
Allen G Li | |||
Yasmin Siddiqui | |||
Donna Wang | |||
Chin-Fang Tang | |||
Jo Nord | |||
P2860 | cites work | The Hallmarks of Cancer | Q221226 |
Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis | Q24679619 | ||
Regulation of immune responses by TGF-beta | Q28271433 | ||
Molecular predictors of survival after adjuvant chemotherapy for colon cancer | Q28363159 | ||
Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis | Q28592128 | ||
Tenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1 | Q28771732 | ||
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion | Q29547317 | ||
A multigenic program mediating breast cancer metastasis to bone | Q29614308 | ||
The STATs of cancer--new molecular targets come of age | Q29614601 | ||
Cancer statistics, 2004 | Q29620739 | ||
TGF-beta in the evolution and resolution of inflammatory and immune processes. Introduction | Q33804106 | ||
TGF-beta and cancer. | Q33804136 | ||
Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis | Q33840435 | ||
STAT signaling in head and neck cancer | Q33941351 | ||
Role of TGFbeta signaling in skin carcinogenesis | Q34136510 | ||
Measurement of the transit time for cells through the epidermis and stratum corneum of the mouse and guinea-pig | Q34179496 | ||
G1 cell-cycle control and cancer | Q34368858 | ||
Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects | Q34792580 | ||
A mouse model of human oral-esophageal cancer | Q34796816 | ||
Molecular pathogenesis of head and neck squamous cell carcinoma | Q35123594 | ||
Signaling through the epidermal growth factor receptor during the development of malignancy | Q35729447 | ||
Focus on head and neck cancer | Q35749406 | ||
The role of TGF-beta in epithelial malignancy and its relevance to the pathogenesis of oral cancer (part II). | Q35969342 | ||
Evidence for field change in oral cancer based on cytokeratin expression | Q35977034 | ||
High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India | Q35984217 | ||
Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders | Q36376435 | ||
Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder | Q37617085 | ||
Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells | Q38806280 | ||
Transforming growth factor-beta1 increases CXCR4 expression, stromal-derived factor-1alpha-stimulated signalling and human immunodeficiency virus-1 entry in human monocyte-derived macrophages | Q38942138 | ||
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors | Q39646992 | ||
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras | Q40424687 | ||
Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma. | Q40724591 | ||
Gene expression of differentiation-specific keratins (4/13 and 1/10) in normal human buccal mucosa | Q42459252 | ||
Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis. | Q42471910 | ||
Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer | Q44674194 | ||
Missense mutations of the transforming growth factor beta type II receptor in human head and neck squamous carcinoma cells. | Q45345219 | ||
Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer | Q45345242 | ||
Immunohistochemical detection of the H-ras, K-ras, and N-ras oncogenes in squamous cell carcinoma of the head and neck | Q46306270 | ||
Overexpression of transforming growth factor beta1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation | Q47255124 | ||
Mutations of the BRAF gene in squamous cell carcinoma of the head and neck | Q47739089 | ||
H-ras oncogene mutation and human papillomavirus infection in oral carcinomas. | Q53471461 | ||
Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity. | Q54707698 | ||
Overexpression of cyclin D1 indicates a poor prognosis in squamous cell carcinoma of the head and neck | Q73353859 | ||
Mutation and downregulation of the transforming growth factor beta type II receptor gene in primary squamous cell carcinomas of the head and neck | Q73934582 | ||
The progression of invasiveness regarding the role of transforming growth factor beta receptor type II in gastric cancer | Q73938065 | ||
Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer | Q77948466 | ||
Amplification of wild-type K-ras promotes growth of head and neck squamous cell carcinoma | Q78710253 | ||
Reduced expression of transforming growth factor-beta receptors is an unfavorable prognostic factor in human esophageal squamous cell carcinoma | Q78892542 | ||
P433 | issue | 10 | |
P921 | main subject | head and neck squamous cell carcinoma | Q18348812 |
P304 | page(s) | 1331-1342 | |
P577 | publication date | 2006-05-01 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma | |
P478 | volume | 20 |
Q37350394 | A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors |
Q36464443 | Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis |
Q90524090 | Activation of S6 signaling is associated with cell survival and multinucleation in hyperplastic skin after epidermal loss of AURORA-A Kinase |
Q35127700 | Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression |
Q42592447 | Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma. |
Q83320051 | Alterations of Smad expression and activation in defining 2 subtypes of human head and neck squamous cell carcinoma |
Q33623668 | An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter |
Q27026169 | Animal models to study the mutational landscape for oral cavity and oropharyngeal cancers |
Q33568163 | Association between TGFBR1*6A and osteosarcoma: a Chinese case-control study |
Q37227206 | Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer. |
Q61500110 | BMP7 Signaling in -Deficient Stromal Cells Provokes Epithelial Carcinogenesis |
Q38051156 | Basic consideration of research strategies for head and neck cancer. |
Q33902520 | Biomarker and Tumor Responses of Oral Cavity Squamous Cell Carcinoma to Trametinib: A Phase II Neoadjuvant Window-of-Opportunity Clinical Trial |
Q24319683 | CIP2A inhibits PP2A in human malignancies |
Q37549392 | CLIC4 regulates TGF-β-dependent myofibroblast differentiation to produce a cancer stroma |
Q46489977 | Chronic Inflammation in Skin Malignancies |
Q34156955 | Comparative analysis of algorithms for integration of copy number and expression data |
Q28256121 | Comprehensive genomic characterization of head and neck squamous cell carcinomas |
Q43630638 | Conditional expression of the dominant-negative TGF-β receptor type II elicits lingual epithelial hyperplasia in transgenic mice |
Q55465923 | Cooperation Between Pten and Smad4 in Murine Salivary Gland Tumor Formation and Progression. |
Q37656680 | De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones. |
Q41807406 | Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta |
Q37158601 | Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling |
Q42870965 | Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas |
Q90627871 | Distinct roles of PIK3CA in the enrichment and maintenance of cancer stem cells in head and neck squamous cell carcinoma |
Q37274623 | Dysregulated molecular networks in head and neck carcinogenesis |
Q28075996 | Dysregulation of TGFβ1 Activity in Cancer and Its Influence on the Quality of Anti-Tumor Immunity |
Q39442395 | ERK1/2 regulation of CD44 modulates oral cancer aggressiveness |
Q36539734 | ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas |
Q35172778 | Emerging strategies for the early detection and prevention of head and neck squamous cell cancer |
Q37200826 | Epithelial stem cell mutations that promote squamous cell carcinoma metastasis |
Q36964214 | Exosome-mediated transfer from the tumor microenvironment increases TGFβ signaling in squamous cell carcinoma |
Q30010225 | Four-gene expression model predictive of lymph node metastases in oral squamous cell carcinoma. |
Q37171910 | Genomics of lung cancer. |
Q35156109 | Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis |
Q41834933 | HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion |
Q93132011 | Hair follicle regeneration suppresses Ras-driven oncogenic growth |
Q37197348 | Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues |
Q39802740 | Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway |
Q34488339 | In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1. |
Q40383441 | Inactivation of TGFβ receptor II signalling in pancreatic epithelial cells promotes acinar cell proliferation, acinar-to-ductal metaplasia and fibrosis during pancreatitis. |
Q52587547 | Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing. |
Q36806950 | Inhibition of TGF-β enhances the in vivo antitumor efficacy of EGF receptor-targeted therapy |
Q33626364 | Keratin promoter based gene manipulation in the murine conducting airway |
Q39790068 | Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression |
Q38609786 | Keratoacanthoma: a distinct entity? |
Q64290298 | Knowing the tumour microenvironment to optimise immunotherapy |
Q35722714 | Loss of TGF-β signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation. |
Q30482281 | Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia |
Q35894697 | Loss of transforming growth factor beta type II receptor increases aggressive tumor behavior and reduces survival in lung adenocarcinoma and squamous cell carcinoma |
Q42949508 | Lung adenocarcinoma invasion in TGFbetaRII-deficient cells is mediated by CCL5/RANTES. |
Q39177663 | Macrophage coculture enhanced invasion of gastric cancer cells via TGF-β and BMP pathways. |
Q36863089 | MicroRNA-135b acts as a tumor promoter by targeting the hypoxia-inducible factor pathway in genetically defined mouse model of head and neck squamous cell carcinoma |
Q55554558 | Microbiota, Epithelium, Inflammation, and TGF-β Signaling: An Intricate Interaction in Oncogenesis. |
Q28082815 | Molecular Aspects of Head and Neck Cancer Therapy |
Q38069455 | Molecular and cellular processes underlying the hallmarks of head and neck cancer. |
Q28728638 | Molecular changes in the multistage pathogenesis of head and neck cancer |
Q53176144 | Mouse Models for Studying Oral Cancer: Impact in the Era of Cancer Immunotherapy. |
Q39537487 | Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines |
Q36078222 | Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma. |
Q35120893 | NF-κB addiction and its role in cancer: 'one size does not fit all'. |
Q37382687 | Nuclear NF-kappaB p65 phosphorylation at serine 276 by protein kinase A contributes to the malignant phenotype of head and neck cancer. |
Q37176596 | Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling |
Q37025086 | PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer |
Q39924024 | PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production |
Q47329309 | Paradoxical roles of TGF-β signaling in suppressing and promoting squamous cell carcinoma |
Q37192194 | Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis |
Q51174218 | Progression of human bronchioloalveolar carcinoma to invasive adenocarcinoma is modeled in a transgenic mouse model of K-ras-induced lung cancer by loss of the TGF-β type II receptor. |
Q37379223 | Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway. |
Q38948512 | Regulatory T Cells and Cancer: A Two-Sided Story |
Q38264091 | Role of MTA1 in head and neck cancers |
Q35994228 | Role of phosphatidylinositol-3-kinase pathway in head and neck squamous cell carcinoma |
Q37339711 | Roles of TGFbeta in metastasis |
Q26783920 | Single and Multiple Gene Manipulations in Mouse Models of Human Cancer |
Q41761816 | Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation |
Q37198686 | Smad4 loss in mouse keratinocytes leads to increased susceptibility to UV carcinogenesis with reduced Ercc1-mediated DNA repair |
Q37403133 | Smad4: gatekeeper gene in head and neck squamous cell carcinoma |
Q28079488 | Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker Studies |
Q36678582 | Systems biology-defined NF-kappaB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status |
Q33936542 | TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression |
Q39569862 | TGF-beta1 promotes migration and invasion of salivary adenoid cystic carcinoma |
Q27025590 | TGF-β - an excellent servant but a bad master |
Q36210115 | TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers |
Q46183468 | TGF-β inhibits metastasis in late stage human squamous cell carcinoma of the skin by a mechanism that does not involve Id1 |
Q35871985 | TGF-β promotes heterogeneity and drug resistance in squamous cell carcinoma |
Q38796618 | TGF-β signaling in liver and gastrointestinal cancers |
Q50183694 | TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma. |
Q37741025 | TGFbeta and cancer metastasis: an inflammation link. |
Q28288866 | TGFbeta in Cancer |
Q37777022 | TGFβ signaling in head and neck squamous cell carcinoma |
Q34999356 | TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium. |
Q34248613 | TGM3, a candidate tumor suppressor gene, contributes to human head and neck cancer |
Q36462348 | Targeting the TGFβ signalling pathway in disease |
Q37672605 | Temporal characterization of lymphatic metastasis in an orthotopic mouse model of oral cancer |
Q34356297 | Tgf-beta signaling pathway in lung adenocarcinoma invasion. |
Q42154608 | The HPV16 E6 oncoprotein and UVB irradiation inhibit the tumor suppressor TGFβ pathway in the epidermis of the K14E6 transgenic mouse |
Q36483794 | The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth |
Q36522719 | The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models |
Q37189951 | The Role of the NF-kappaB Transcriptome and Proteome as Biomarkers in Human Head and Neck Squamous Cell Carcinomas |
Q36462328 | The complexities of TGF-β action during mammary and squamous cell carcinogenesis |
Q36659339 | The molecular pathogenesis of head and neck squamous cell carcinoma |
Q33630845 | The roles of TGFβ in the tumour microenvironment |
Q39493744 | Tobacco-specific carcinogen nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces AKT activation in head and neck epithelia |
Q37326107 | Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer? |
Q37582137 | Transforming growth factor β1 enhances stemness of head and neck squamous cell carcinoma cells through activation of Wnt signaling |
Q37916975 | Transforming growth factor-β in the gastrointestinal and hepatic tumor microenvironment. |
Q58767650 | Transforming growth factor-β signaling in head and neck squamous cell carcinoma: Insights into cellular responses |
Q34998769 | Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma |
Q34363852 | Use of a TGFβ type I receptor inhibitor in mouse skin carcinogenesis reveals a dual role for TGFβ signaling in tumor promotion and progression |
Q38795514 | miR-373 Inhibits Glioma Cell U251 Migration and Invasion by Down-Regulating CD44 and TGFBR2. |
Search more.