Foxa1 and Foxa2 regulate bile duct development in mice

scientific article

Foxa1 and Foxa2 regulate bile duct development in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI38201
P932PMC publication ID2689124
P698PubMed publication ID19436110
P5875ResearchGate publication ID24421539

P2093author name stringPeter White
Klaus H Kaestner
Geetu Tuteja
Nir Rubins
Sara Sackett
Zhaoyu Li
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The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesisQ28590424
Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissuesQ28593613
Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent mannerQ28594838
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Transcriptional networks in the liver: hepatocyte nuclear factor 6 function is largely independent of Foxa2.Q33924940
Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyteQ33964626
Regulation and deregulation of cholangiocyte proliferationQ34010481
Regulation of cholangiocyte proliferationQ34229378
The pathobiology of biliary epitheliaQ34618489
The initiation of liver development is dependent on Foxa transcription factorsQ34650705
Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.Q34657904
Regulatory phases of early liver development: paradigms of organogenesisQ34718150
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stressQ34801719
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Mechanisms controlling early development of the liverQ35029647
Development of the biliary tractQ35029670
Hepatocyte growth factor attenuates liver fibrosis induced by bile duct ligationQ35088302
Regulation and function of trefoil factor family 3 expression in the biliary treeQ35103575
IL-6 signal transduction and its physiological roles: the signal orchestration modelQ35104022
Pathophysiological factors affecting CAR gene expression.Q35620628
Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cellQ35666145
The development and compensation of biliary cirrhosis in interleukin-6-deficient miceQ35810127
The cholangiopathies: disorders of biliary epitheliaQ35936575
Pathophysiology of cholangiopathiesQ36066829
The making of the liver: developmental competence in foregut endoderm and induction of the hepatogenic programQ36241190
The immunophysiology of biliary epitheliumQ36249666
Six members of the mouse forkhead gene family are developmentally regulatedQ36481228
The Foxa family of transcription factors in development and metabolismQ36565815
Proliferating cholangiocytes: a neuroendocrine compartment in the diseased liverQ36714754
The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distributionQ38309705
Glucocorticoid receptor, C/EBP, HNF3, and protein kinase A coordinately activate the glucocorticoid response unit of the carbamoylphosphate synthetase I geneQ39576419
Glucocorticoid suppression of CX3CL1 (fractalkine) by reduced gene promoter recruitment of NF-kappaB.Q40019198
Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell lineQ40921479
Lipopolysaccharide induces cholangiocyte proliferation via an interleukin-6-mediated activation of p44/p42 mitogen-activated protein kinaseQ40964415
Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesisQ42443043
Regulation of fibroblast proliferation by Kupffer cells and monocytesQ44867328
Activation of interleukin-6/STAT3 in rat cholangiocyte proliferation induced by lipopolysaccharideQ46467526
Signaling mechanisms through gp130: a model of the cytokine systemQ47992455
Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork headQ48232472
Foxa2 integrates the transcriptional response of the hepatocyte to fasting.Q51512450
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.Q51991474
Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.Q52522262
IL-6 modulates hepatocyte proliferation via induction of HGF/p21cip1: regulation by SOCS3.Q52567193
Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.Q54606882
Human biliary epithelial cells secrete and respond to cytokines and hepatocyte growth factors in vitro: interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitroQ72094183
Acute obstructive cholangiopathy in interleukin-6 deficient mice: compensation by leukemia inhibitory factor (LIF) suggests importance of gp-130 signaling in the ductular reactionQ73880869
Interleukin-6, hepatocyte growth factor, and their receptors in biliary epithelial cells during a type I ductular reaction in mice: interactions between the periductal inflammatory and stromal cells and the biliary epitheliumQ77485741
Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosisQ81363230
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1537-1545
P577publication date2009-05-11
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleFoxa1 and Foxa2 regulate bile duct development in mice.
P478volume119

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