review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Narcisa Martínez Quiles | Q57209673 |
María Benito-León | Q86288127 | ||
Philip R Hardwidge | Q88106457 | ||
P2093 | author name string | Leigh Ann Feuerbacher | |
P2860 | cites work | Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency | Q21131164 |
Activation of Rac1 by a Crk SH3-binding protein, DOCK180 | Q22007972 | ||
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function | Q24293521 | ||
Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP | Q24294671 | ||
IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7 | Q24297066 | ||
Inhibition of TLR signaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs | Q24299272 | ||
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation | Q24301668 | ||
Isolation and chromosomal localization of CRKL, a human crk-like gene | Q24312793 | ||
c-Abl kinase regulates the protein binding activity of c-Crk | Q24595669 | ||
Evolution of SH2 domains and phosphotyrosine signalling networks | Q24620411 | ||
Two species of human CRK cDNA encode proteins with distinct biological activities | Q24629936 | ||
The adaptor protein Crk in immune response | Q26849320 | ||
Phosphoregulation of the WAVE regulatory complex and signal integration | Q26863403 | ||
Elucidation of the binding preferences of peptide recognition modules: SH3 and PDZ domains | Q27006986 | ||
Under lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processes | Q27009455 | ||
The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal | Q27643275 | ||
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK | Q27644837 | ||
Structural basis for regulation of the Crk signaling protein by a proline switch | Q27666184 | ||
Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII | Q27679069 | ||
Shigella: a model of virulence regulation in vivo | Q27687005 | ||
Moving parts: how the adaptor protein CRK is regulated and regulates | Q58175399 | ||
Phosphorylation of tyrosine 474 of the enteropathogenic Escherichia coli (EPEC) Tir receptor molecule is essential for actin nucleating activity and is preceded by additional host modifications | Q74649176 | ||
Enteropathogenic Escherichia coli induces modification of the focal adhesions of infected host cells | Q77936920 | ||
Translocation of CrkL to focal adhesions mediates integrin-induced migration downstream of Src family kinases | Q39743634 | ||
A Novel FRET-Based Biosensor for the Measurement of BCR-ABL Activity and Its Response to Drugs in Living Cells | Q39852216 | ||
Abl tyrosine kinases are required for infection by Shigella flexneri | Q39962325 | ||
Proapoptotic function of the nuclear Crk II adaptor protein. | Q40086531 | ||
Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis | Q40120615 | ||
Tir phosphorylation and Nck/N-WASP recruitment by enteropathogenic and enterohaemorrhagic Escherichia coli during ex vivo colonization of human intestinal mucosa is different to cell culture models | Q40138256 | ||
Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway | Q40806872 | ||
Characterization, partial purification, and peptide sequencing of p130,the main phosphoprotein associated with v-Crk oncoprotein | Q41407792 | ||
A role for N-WASP in invasin-promoted internalisation. | Q41473776 | ||
Attachment and penetration of Escherichia coli into intestinal epithelium of the ileum in newborn pigs | Q41577121 | ||
Crk and CrkL adaptor proteins: networks for physiological and pathological signaling | Q41942048 | ||
v-Crk regulates membrane dynamics and Rac activation | Q42113913 | ||
Conformation of the EPEC Tir protein in solution: investigating the impact of serine phosphorylation at positions 434/463. | Q42143260 | ||
The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. | Q42677853 | ||
Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers actin pedestal formation | Q42827785 | ||
The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene | Q43900370 | ||
Phosphoserine modification of the enteropathogenic Escherichia coli Tir molecule is required to trigger conformational changes in Tir and efficient pedestal elongation | Q43910848 | ||
A tyrosine-phosphorylated 12-amino-acid sequence of enteropathogenic Escherichia coli Tir binds the host adaptor protein Nck and is required for Nck localization to actin pedestals | Q43936783 | ||
BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl | Q44040285 | ||
Characterization of p47gag-crk, a novel oncogene product with sequence similarity to a putative modulatory domain of protein-tyrosine kinases and phospholipase C. | Q44041117 | ||
Analysis of the mechanisms of Salmonella-induced actin assembly during invasion of host cells and intracellular replication | Q44447381 | ||
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. | Q45986472 | ||
Nck-independent actin assembly is mediated by two phosphorylated tyrosines within enteropathogenic Escherichia coli Tir. | Q46424888 | ||
Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells | Q48042079 | ||
Structural biology: CrkL is not Crk-like | Q49217724 | ||
When Shigella tells the cell to hang on. | Q50053392 | ||
Role of CrkII in Fcgamma receptor-mediated phagocytosis | Q50335857 | ||
miR-126 in human cancers: clinical roles and current perspectives | Q38173789 | ||
The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells. | Q38662412 | ||
EspC promotes epithelial cell detachment by enteropathogenic Escherichia coli via sequential cleavages of a cytoskeletal protein and then focal adhesion proteins | Q39014117 | ||
Type III secretion translocon assemblies that attenuate Yersinia virulence. | Q39218275 | ||
Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals | Q39254264 | ||
Recruitment of cytoskeletal and signaling proteins to enteropathogenic and enterohemorrhagic Escherichia coli pedestals | Q39520034 | ||
Signaling through scaffold, anchoring, and adaptor proteins | Q28131792 | ||
DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines | Q28209633 | ||
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases | Q28218689 | ||
CRK proto-oncogene maps to human chromosome band 17p13 | Q28262715 | ||
The language of SH2 domain interactions defines phosphotyrosine-mediated signal transduction | Q28266221 | ||
Protein delivery into eukaryotic cells by type III secretion machines | Q28276443 | ||
p130Cas: a key signalling node in health and disease | Q28282363 | ||
p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene | Q28290078 | ||
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site | Q28304850 | ||
SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl | Q28307277 | ||
A novel viral oncogene with structural similarity to phospholipase C | Q28307371 | ||
Unc119 protects from Shigella infection by inhibiting the Abl family kinases | Q28475302 | ||
The enteropathogenic E. coli (EPEC) Tir effector inhibits NF-κB activity by targeting TNFα receptor-associated factors | Q28478223 | ||
Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome | Q28505391 | ||
CrkL functions as a nuclear adaptor and transcriptional activator in Bcr-Abl-expressing cells | Q28566499 | ||
Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells | Q28590934 | ||
Environmental sensing through focal adhesions | Q29615211 | ||
Crk at the quarter century mark: perspectives in signaling and cancer | Q30009510 | ||
Models of crk adaptor proteins in cancer | Q30009961 | ||
Commentary: The carboxyl-terminal Crk SH3 domain: Regulatory strategies and new perspectives | Q30010069 | ||
Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics | Q30010077 | ||
Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation | Q30010491 | ||
Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals | Q30157067 | ||
Cardiovascular and craniofacial defects in Crk-null mice | Q30159699 | ||
Solution structure and folding characteristics of the C-terminal SH3 domain of c-Crk-II. | Q30159725 | ||
WAVE2 signaling mediates invasion of polarized epithelial cells by Salmonella typhimurium | Q30160225 | ||
The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle | Q30160265 | ||
Apoptotic regulation by the Crk adapter protein mediated by interactions with Wee1 and Crm1/exportin | Q30167608 | ||
Crk family adaptors-signalling complex formation and biological roles | Q30167857 | ||
Crk family adaptor proteins trans-activate c-Abl kinase | Q30168146 | ||
Mutant mice lacking Crk-II caused by the gene trap insertional mutagenesis: Crk-II is not essential for embryonic development | Q30175280 | ||
Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins | Q30175408 | ||
Activation of a CrkL-stat5 signaling complex by type I interferons. | Q30175923 | ||
v-Crk, an effector of the nerve growth factor signaling pathway, delays apoptotic cell death in neurotrophin-deprived PC12 cells | Q30176670 | ||
A potential SH3 domain-binding site in the Crk SH2 domain | Q30176843 | ||
Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia | Q30194068 | ||
Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides | Q30194700 | ||
Identification and Characterization of a High-Affinity Interaction Between v-Crk and Tyrosine-Phosphorylated Paxillin in CT10-Transformed Fibroblasts | Q30194902 | ||
CAS/Crk signalling mediates uptake of Yersinia into human epithelial cells | Q30306838 | ||
Cas, Fak and Pyk2 function in diverse signaling cascades to promote Yersinia uptake. | Q30309555 | ||
Distinct mechanisms of integrin binding by Yersinia pseudotuberculosis adhesins determine the phagocytic response of host macrophages | Q30437985 | ||
Abelson tyrosine kinase facilitates Salmonella enterica serovar Typhimurium entry into epithelial cells | Q30439306 | ||
Invasion of host cells by Salmonella typhimurium requires focal adhesion kinase and p130Cas | Q30441301 | ||
Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells | Q30443448 | ||
Mechanisms of Salmonella entry into host cells | Q30443924 | ||
Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells | Q33292526 | ||
Mechanism of Shigella entry into epithelial cells | Q33536573 | ||
Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo | Q33621525 | ||
Activation of the WAVE complex by coincident signals controls actin assembly | Q33638097 | ||
Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements | Q34177961 | ||
EspO1-2 regulates EspM2-mediated RhoA activity to stabilize formation of focal adhesions in enterohemorrhagic Escherichia coli-infected host cells | Q34586498 | ||
Emerging roles for crk in human cancer | Q34972759 | ||
Tails of two Tirs: actin pedestal formation by enteropathogenic E. coli and enterohemorrhagic E. coli O157:H7. | Q35077208 | ||
Crk adaptors negatively regulate actin polymerization in pedestals formed by enteropathogenic Escherichia coli (EPEC) by binding to Tir effector | Q35133400 | ||
Manipulation of the host actin cytoskeleton by Salmonella--all in the name of entry | Q36032340 | ||
Perspective: Dynamics of receptor tyrosine kinase signaling complexes | Q36146861 | ||
Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly | Q36322209 | ||
Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells | Q36382504 | ||
Crk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton | Q36443397 | ||
Enteropathogenic Escherichia coli use redundant tyrosine kinases to form actin pedestals. | Q37031466 | ||
A new twist to adaptor proteins contributes to regulation of lymphocyte cell signaling | Q37206781 | ||
Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB (NF-κB) pathway | Q37348920 | ||
Bacterial type III effectors inhibit cell lifting by targeting integrin-linked kinase | Q37520088 | ||
Adhesive mechanisms of Salmonella enterica | Q37873833 | ||
Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton | Q37942128 | ||
Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli | Q38127457 | ||
Strategies used by Yersinia enterocolitica to evade killing by the host: thinking beyond Yops. | Q38163691 | ||
Integrating actin dynamics, mechanotransduction and integrin activation: the multiple functions of actin binding proteins in focal adhesions | Q38164160 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | peptide | Q172847 |
transport protein | Q2111029 | ||
proto-oncogene protein | Q66020913 | ||
neoplasm protein | Q66894191 | ||
host microbial interaction | Q68260314 | ||
P304 | page(s) | 372901 | |
P577 | publication date | 2014-11-25 | |
P1433 | published in | BioMed Research International | Q17509958 |
P1476 | title | Contribution of Crk adaptor proteins to host cell and bacteria interactions | |
P478 | volume | 2014 |
Q47102643 | Phosphoproteomics of cAMP signaling of Bordetella adenylate cyclase toxin in mouse dendritic cells |
Q27319429 | Pseudomonas aeruginosa ExoT Induces Atypical Anoikis Apoptosis in Target Host Cells by Transforming Crk Adaptor Protein into a Cytotoxin |
Q91985737 | The Crk adapter protein is essential for Drosophila embryogenesis, where it regulates multiple actin-dependent morphogenic events |
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