The Edg family G protein-coupled receptors for lysophospholipids: their signaling properties and biological activities

scientific article

The Edg family G protein-coupled receptors for lysophospholipids: their signaling properties and biological activities is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1093/OXFORDJOURNALS.JBCHEM.A003163
P698PubMed publication ID12038970

P2093author name stringYoh Takuwa
Naotoshi Sugimoto
Noriko Takuwa
P2860cites workSphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4Q28215211
Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.Q31370338
P433issue6
P921main subjectG protein-coupled receptorQ38173
P304page(s)767-771
P577publication date2002-06-01
P1433published inJournal of BiochemistryQ6294839
P1476titleThe Edg family G protein-coupled receptors for lysophospholipids: their signaling properties and biological activities
P478volume131

Reverse relations

cites work (P2860)
Q36930924Autotaxin (ATX): a multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular properties
Q50074055Autotaxin-Lysophosphatidic Acid: From Inflammation to Cancer Development
Q34518525Bioactive lipids, LPC and LPA, are novel prometastatic factors and their tissue levels increase in response to radio/chemotherapy
Q37618930Capillary endothelial Na(+), K(+), ATPase transporter homeostasis and a new theory for migraine pathophysiology
Q30423883Dendritic cell sphingosine 1-phosphate receptor-3 regulates Th1-Th2 polarity in kidney ischemia-reperfusion injury
Q35600796Discovery of new G protein-coupled receptors for lipid mediators
Q28477728Dynamic changes in neurexins' alternative splicing: role of Rho-associated protein kinases and relevance to memory formation
Q53352651Dyslipidemia regulates thrombospondin-1-induced vascular smooth muscle cell chemotaxis.
Q36727390Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer
Q39657959Effects of lysophosphatidic acid on the in vitro proliferation and differentiation of a novel porcine preadipocyte cell line
Q26744051Emerging role of sphingosine-1-phosphate signaling in head and neck squamous cell carcinoma
Q46635848Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cells
Q24650905Expression analysis of G Protein-Coupled Receptors in mouse macrophages
Q39141595Expression and role of GPR87 in urothelial carcinoma of the bladder
Q24536047Fly and mammalian lipid phosphate phosphatase isoforms differ in activity both in vitro and in vivo
Q92540195G Protein-Coupled Receptor Systems and Their Role in Cellular Senescence
Q47174627G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts
Q37408559G protein-linked signaling pathways in bipolar and major depressive disorders
Q26767279G-Protein-Coupled Lysophosphatidic Acid Receptors and Their Regulation of AKT Signaling
Q36248054G-protein-coupled receptor deorphanizations
Q38419321Gene expression profiles of apoptotic neurons.
Q34053101HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate
Q36673210Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor VEGF, while angiopoietin 1 and sphingosine 1-phosphate inhibit hantavirus-directed permeability
Q34254350High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3, Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients
Q93019383Hyperglycemia-Triggered Sphingosine-1-Phosphate and Sphingosine-1-Phosphate Receptor 3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization
Q36789822Identification of non-lipid LPA3 antagonists by virtual screening
Q34150494Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection.
Q39740344Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform
Q38339058Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes
Q92447143Iron and Sphingolipids as Common Players of (Mal)Adaptation to Hypoxia in Pulmonary Diseases
Q84984868Loss of Arnt (Hif1β) in mouse epidermis triggers dermal angiogenesis, blood vessel dilation and clotting defects
Q35974518Lys39-Lysophosphatidate Carbonyl Oxygen Interaction Locks LPA1 N-terminal Cap to the Orthosteric Site and partners Arg124 During Receptor Activation
Q30252513Lysolecithin as feed additive enhances collagen expression and villus length in the jejunum of broiler chickens
Q44429395Lysophosphatidic Acid Signals through Mitogen-Activated Protein Kinase-Extracellular Signal Regulated Kinase in Ovarian Theca Cells Expressing the LPA1/edg2-Receptor: Involvement of a Nonclassical Pathway?
Q36330107Lysophosphatidic Acid and Sphingosine-1-Phosphate: A Concise Review of Biological Function and Applications for Tissue Engineering.
Q37433301Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrier disruption and lung injury
Q36569198Lysophosphatidic acid increases soluble ST2 expression in mouse lung and human bronchial epithelial cells
Q40007704Lysophosphatidic acid inhibits neuronal differentiation of neural stem/progenitor cells derived from human embryonic stem cells.
Q39783008Lysophosphatidic acid receptor expression in chronic lymphocytic leukemia leads to cell survival mediated though vascular endothelial growth factor expression
Q37139302Lysophosphatidic acid signaling in airway epithelium: role in airway inflammation and remodeling
Q45232420Lysophosphatidic acid stimulates fas ligand microvesicle release from ovarian cancer cells
Q33829692Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget
Q40103223Meta-analysis of primary target genes of peroxisome proliferator-activated receptors
Q60721864Modulation of LPA Receptor Expression in the Human Brain Following Neurotrauma
Q35559631Molecular mechanisms of lysophosphatidic acid action
Q38660494Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer
Q35538979New Aspects of Neurotransmitter Release and Exocytosis: Rho-Kinase-Dependent Myristoylated Alanine-Rich C-Kinase Substrate Phosphorylation and Regulation of Neurofilament Structure in Neuronal Cells
Q37772650New insights into the mechanism of fibroblast to myofibroblast transformation and associated pathologies
Q45951802Phytosphingosine-1-phosphate represses the hydrogen peroxide-induced activation of c-Jun N-terminal kinase in human dermal fibroblasts through the phosphatidylinositol 3-kinase/Akt pathway.
Q52939000Possible effect of lysophosphatidic acid on cell proliferation and involvement of lysophosphatidic acid and lysophosphatidic acid receptors in mechanical stretch-induced mitogen-activated protein kinase.
Q44691572Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study
Q42458821Regulation of phospholipase D2 activity by protein kinase C alpha
Q91654129Regulation of tumor cell - Microenvironment interaction by the autotaxin-lysophosphatidic acid receptor axis
Q46353217Role of sphingosine 1-phosphate receptor expression in eosinophils of patients with allergic rhinitis, and effect of topical nasal steroid treatment on this receptor expression
Q41814495Role of vascular and lymphatic endothelial cells in hantavirus pulmonary syndrome suggests targeted therapeutic approaches
Q24646539S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells
Q37699403S1P induced changes in epithelial ovarian cancer proteolysis, invasion, and attachment are mediated by Gi and Rac.
Q45066703S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells
Q35675184Sphingolipid signaling and hematopoietic malignancies: to the rheostat and beyond
Q30278837Sphingosine 1-Phosphate Receptor 3-Deficient Dendritic Cells Modulate Splenic Responses to Ischemia-Reperfusion Injury
Q46976738Sphingosine 1-phosphate induces EGFR expression via Akt/NF-kappaB and ERK/AP-1 pathways in rat vascular smooth muscle cells
Q46969633Sphingosine-1-phosphate induces COX-2 expression via PI3K/Akt and p42/p44 MAPK pathways in rat vascular smooth muscle cells
Q90642956Sphingosine-1-phosphate induces islet β-cell proliferation and decreases cell apoptosis in high-fat diet/streptozotocin diabetic mice
Q54344488Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.
Q43265790Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with patient survival
Q33757076Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
Q41986585The Role of the Endothelium in HPS Pathogenesis and Potential Therapeutic Approaches
Q43236003The expression level of sphingosine-1-phosphate receptor type 1 is related to MIB-1 labeling index and predicts survival of glioblastoma patients
Q37711207The gep proto-oncogene Gα12 mediates LPA-stimulated activation of CREB in ovarian cancer cells
Q45229482The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells.
Q37236249The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy
Q39705488Translocation of Fas by LPA prevents ovarian cancer cells from anti-Fas-induced apoptosis
Q35264010Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1 - Jekyll Hidden behind Hyde
Q34388874Virus interactions with endothelial cell receptors: implications for viral pathogenesis
Q42814296Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts
Q39882004miRNA expression profiling of Epstein-Barr virus-associated NKTL cell lines by Illumina deep sequencing

Search more.