| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2006PNAS..103.9661Y |
| P356 | DOI | 10.1073/PNAS.0603251103 |
| P8608 | Fatcat ID | release_hidlfezvkvdhjgqmtzzynhdsae |
| P953 | full work available at URL | https://europepmc.org/articles/pmc1475798?pdf=render |
| P932 | PMC publication ID | 1475798 |
| P698 | PubMed publication ID | 16766657 |
| P5875 | ResearchGate publication ID | 7016152 |
| P7228 | access restriction status | open access | Q232932 |
| P2093 | author name string | Takeshi Murakami | |
| Koji Yanai | |||
| Mervyn Bibb | |||
| P2860 | cites work | A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action | Q21203780 |
| The penicillin gene cluster is amplified in tandem repeats linked by conserved hexanucleotide sequences | Q24563186 | ||
| Basic local alignment search tool | Q25938991 | ||
| Artemis: sequence visualization and annotation | Q27861024 | ||
| Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11 | Q28274408 | ||
| Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2) | Q29547307 | ||
| Identification of genes that are associated with DNA repeats in prokaryotes | Q29615790 | ||
| PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin | Q30764407 | ||
| AUD4, a new amplifiable element from Streptomyces lividans | Q30831678 | ||
| A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster | Q31105807 | ||
| Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. | Q33227202 | ||
| Genus-specific protein binding to the large clusters of DNA repeats (short regularly spaced repeats) present in Sulfolobus genomes | Q33965230 | ||
| Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis | Q33965431 | ||
| Chromosome evolution in the Thermotogales: large-scale inversions and strain diversification of CRISPR sequences | Q33994248 | ||
| The relationship between base composition and codon usage in bacterial genes and its use for the simple and reliable identification of protein-coding sequences | Q34245641 | ||
| Production and isolation of a new antibiotic: kanamycin. | Q34538679 | ||
| The very large amplifiable element AUD2 from Streptomyces lividans 66 has insertion sequence-like repeats at its ends | Q36726953 | ||
| Rapid method for determination of kanamycin and dibekacin in serum by use of high-pressure liquid chromatography | Q39850433 | ||
| Genetic instability of the Streptomyces chromosome | Q41713848 | ||
| Increased production of aminoglycosides associated with amplified antibiotic resistance genes | Q43537419 | ||
| SCP1, a 356,023 bp linear plasmid adapted to the ecology and developmental biology of its host, Streptomyces coelicolor A3(2). | Q44792471 | ||
| A plausible mechanism for large-scale chromosomal DNA amplification in streptomycetes | Q45259120 | ||
| The kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus | Q48178045 | ||
| Limited regions of homology between linear and circular plasmids encoding methylenomycin biosynthesis in two independently isolated streptomycetes | Q48248658 | ||
| Linear plasmid SLP2 of Streptomyces lividans is a composite replicon | Q48256566 | ||
| Semisynthetic aminoglycoside antibiotics: Development and enzymatic modifications. | Q53981567 | ||
| Mechanisms of aminoglycoside-resistance of Streptomyces harboring resistant genes obtained from antibiotic-producers. | Q54455829 | ||
| Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria. | Q55033791 | ||
| P2507 | corrigendum / erratum | Correction for Yanai et al. Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus | Q93507705 |
| P433 | issue | 25 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | gene cluster | Q1501261 |
| Streptomyces kanamyceticus | Q7623387 | ||
| kanamycin A | Q27094615 | ||
| P1104 | number of pages | 6 | |
| P6954 | online access status | open access | Q232932 |
| P304 | page(s) | 9661-9666 | |
| P577 | publication date | 2006-06-09 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus | |
| P478 | volume | 103 |
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| Q35919360 | A streamlined metabolic pathway for the biosynthesis of moenomycin A. |
| Q35229269 | A system for the targeted amplification of bacterial gene clusters multiplies antibiotic yield in Streptomyces coelicolor |
| Q39129279 | Advancement in bioprocess technology: parallels between microbial natural products and cell culture biologics |
| Q42181821 | An insight into the "-omics" based engineering of streptomycetes for secondary metabolite overproduction |
| Q26784492 | Antibacterial Discovery and Development: From Gene to Product and Back |
| Q37553896 | Bacterial gene amplification: implications for the evolution of antibiotic resistance |
| Q36772394 | Biosynthesis of aminocyclitol-aminoglycoside antibiotics and related compounds |
| Q33639051 | Chromosomal instability in Streptomyces avermitilis: major deletion in the central region and stable circularized chromosome |
| Q42921711 | Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production |
| Q34377459 | Combined gene cluster engineering and precursor feeding to improve gougerotin production in Streptomyces graminearus. |
| Q64983927 | Comparison of Strategies to Overcome Drug Resistance: Learning from Various Kingdoms. |
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| Q39519648 | Discovery of Unusual Biaryl Polyketides by Activation of a Silent Streptomyces venezuelae Biosynthetic Gene Cluster. |
| Q48096595 | Discovery of a new diol-containing polyketide by heterologous expression of a silent biosynthetic gene cluster from Streptomyces lavendulae FRI-5. |
| Q49789963 | Diverse genetic error modes constrain large-scale bio-based production. |
| Q36895777 | Double trouble: medical implications of genetic duplication and amplification in bacteria |
| Q34076725 | Duplication of partial spinosyn biosynthetic gene cluster in Saccharopolyspora spinosa enhances spinosyn production |
| Q38806940 | Engineering microbial hosts for production of bacterial natural products |
| Q51066350 | Enhanced production of validamycin A in Streptomyces hygroscopicus 5008 by engineering validamycin biosynthetic gene cluster. |
| Q50599552 | Gene Overexpression in Streptomyces hygroscopicus Associated with DNA Amplification. |
| Q93066470 | Generation of Streptomyces hygroscopicus cell factories with enhanced ascomycin production by combined elicitation and pathway-engineering strategies |
| Q34127518 | Genetic factors that influence moenomycin production in streptomycetes |
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| Q34465535 | Genome engineering and direct cloning of antibiotic gene clusters via phage ϕBT1 integrase-mediated site-specific recombination in Streptomyces |
| Q58700584 | Genome guided investigation of antibiotics producing actinomycetales strain isolated from a Macau mangrove ecosystem |
| Q52723702 | Genome plasticity is governed by double strand break DNA repair in Streptomyces. |
| Q54441519 | Genome rearrangements of Streptomyces albus J1074 lead to the carotenoid gene cluster activation. |
| Q41862046 | Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus |
| Q62673366 | Heterologous expression-facilitated natural products’ discovery in actinomycetes |
| Q33757045 | How to discover new antibiotics: harvesting the parvome |
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| Q47154055 | Increased Biosynthetic Gene Dosage in a Genome-Reduced Defensive Bacterial Symbiont |
| Q46474459 | Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy |
| Q40314872 | Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp. |
| Q33829836 | Metabolic engineering for the production of natural products. |
| Q33632035 | Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes |
| Q28484385 | MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models |
| Q37443630 | Multiple and Variable NHEJ-Like Genes Are Involved in Resistance to DNA Damage in Streptomyces ambofaciens. |
| Q51044348 | Multiplexed site-specific genome engineering for overproducing bioactive secondary metabolites in actinomycetes. |
| Q36864791 | Plastic architecture of bacterial genome revealed by comparative genomics of Photorhabdus variants |
| Q91625796 | Secondary metabolites overproduction through transcriptional gene cluster refactoring |
| Q36747325 | Spontaneous amplification of the actinorhodin gene cluster in Streptomyces coelicolor involving native insertion sequence IS466 |
| Q37831207 | Strain improvement in actinomycetes in the postgenomic era. |
| Q27685154 | Structure and activity of NADPH-dependent reductase Q1EQE0 from Streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate |
| Q42095401 | Target genes and structure of the direct repeats in the DNA-binding sequences of the response regulator PhoP in Streptomyces coelicolor |
| Q30781109 | The Role of a Nonribosomal Peptide Synthetase in l-Lysine Lactamization During Capuramycin Biosynthesis. |
| Q45902600 | The resolution and regeneration of a cointegrate plasmid reveals a model for plasmid evolution mediated by conjugation and oriT site-specific recombination. |
| Q39665534 | Widespread interspecies homologous recombination reveals reticulate evolution within the genus Streptomyces. |
| Q42792762 | ZouA, a putative relaxase, is essential for dna amplification in Streptomyces kanamyceticus |
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