Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin.

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Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin. is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1003408
P932PMC publication ID3616902
P698PubMed publication ID23593016
P5875ResearchGate publication ID236207388

P50authorJen-Tsan A ChiQ85447804
P2093author name stringCarolyn Sangokoya
Jennifer F Doss
P2860cites workA novel mammalian iron-regulated protein involved in intracellular iron metabolismQ22253435
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalizationQ24310115
A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNAQ24614690
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MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2Q24655427
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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
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A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulationQ28140006
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Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportinQ28245244
Sequential regulation of ferroportin expression after erythrophagocytosis in murine macrophages: early mRNA induction by haem, followed by iron-dependent protein expressionQ28260693
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasisQ28264540
Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory networkQ28280607
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Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblastsQ28585215
MicroRNAs direct rapid deadenylation of mRNAQ29614566
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Combinatorial mRNA regulation: iron regulatory proteins and iso-iron-responsive elements (Iso-IREs).Q34076054
microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell diseaseQ34360379
Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasisQ34499719
Novel regulation of nuclear factor-YB by miR-485-3p affects the expression of DNA topoisomerase IIα and drug responsivenessQ34715623
Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disordersQ34976084
Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in miceQ35027929
Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxideQ35067691
The molecular mechanism of hepcidin-mediated ferroportin down-regulationQ35901835
Molecular control of vertebrate iron homeostasis by iron regulatory proteinsQ36536936
Forging a field: the golden age of iron biologyQ36742479
Chelation therapy for iron overload.Q36750294
miRNAs get an early start on translational silencingQ36965104
A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression.Q37199839
The molecular basis of hepcidin-resistant hereditary hemochromatosisQ37271055
Regulation of hepcidin and iron-overload diseaseQ37463068
Hepcidin and disorders of iron metabolismQ37795819
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P304page(s)e1003408
P577publication date2013-04-04
P1433published inPLOS GeneticsQ1893441
P1476titleIron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin
P478volume9

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