Genes and abdominal aortic aneurysm

scientific article

Genes and abdominal aortic aneurysm is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.AVSG.2010.09.004
P932PMC publication ID3058859
P698PubMed publication ID21146954
P5875ResearchGate publication ID49672874

P50authorGerard TrompQ37640706
Helena KuivaniemiQ42067412
P2093author name stringIrene Hinterseher
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Stromelysin-1 (matrix metalloproteinase-3) and tissue inhibitor of metalloproteinase-3 are overexpressed in the wall of abdominal aortic aneurysmsQ77559142
Alleles of the alpha-1-antitrypsin phenotype in patients with aortic aneurysmsQ77618805
Increased plasma levels of metalloproteinase-9 are associated with abdominal aortic aneurysmsQ77773046
TIMP-2 and PAI-1 mRNA levels are lower in aneurysmal as compared to athero-occlusive abdominal aortasQ79106762
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The role of human leukocyte antigen genes in the formation of abdominal aortic aneurysmsQ79828391
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Enhanced abdominal aortic aneurysm in TIMP-1-deficient miceQ81339092
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The interleukin-10-1082 'A' allele and abdominal aortic aneurysmsQ81370213
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C-reactive protein (CRP) elevation in patients with abdominal aortic aneurysm is independent of the most important CRP genetic polymorphismQ82174658
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The influence of COX-2 single nucleotide polymorphisms on abdominal aortic aneurysm development and the associated inflammationQ84277404
Is there an association between angiotensin converting enzyme (ACE) genotypes and abdominal aortic aneurysm?Q84590940
Human leukocyte antigen class II immune response genes, female gender, and cigarette smoking as risk and modulating factors in abdominal aortic aneurysmsQ74139397
Acute phase reactants in patients with abdominal aortic aneurysmQ74252599
Association of a variable number of tandem repeats in the endothelial constitutive nitric oxide synthase gene with essential hypertension in JapaneseQ74318376
Involvement of polymorphisms in the chemokine system in the susceptibility for coronary artery disease (CAD). Coincidence of elevated Lp(a) and MCP-1 -2518 G/G genotype in CAD patientsQ74354815
Cytokine pattern in aneurysmal and occlusive disease of the aortaQ43816879
Differential regulation of matrix metalloproteinase activities in abdominal aortic aneurysmsQ43904927
A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and strokeQ44103563
The Glu298Asp polymorphism of the NOS 3 gene as a determinant of the baseline production of nitric oxideQ44164789
Increased risk of the abdominal aortic aneurysm in carriers of the MTHFR 677T alleleQ44318046
Missense variations in the fibulin 5 gene and age-related macular degenerationQ28273364
Overlapping and differential expression of BIG-2, BIG-1, TAG-1, and F3: four members of an axon-associated cell adhesion molecule subgroup of the immunoglobulin superfamilyQ28274972
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Fibulin-2 exhibits high degree of variability, but no structural changes concordant with abdominal aortic aneurysmsQ28293755
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodelingQ28592810
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysmQ28943557
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A common variant of endothelial nitric oxide synthase (Glu298Asp) is an independent risk factor for carotid atherosclerosis.Q32137397
Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control studyQ33252377
Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control studyQ33254545
Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysmsQ33290991
Analysis of tissue inhibitor of metalloproteinase-2 gene polymorphisms in a caucasian population with abdominal aortic aneurysmsQ33360012
Association of PPARgamma allelic variation, osteoprotegerin and abdominal aortic aneurysmQ33575645
Apolipoprotein E genotype is associated with serum C-reactive protein but not abdominal aortic aneurysmQ33756098
Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migrationQ33863783
Diabetes and the abdominal aortic aneurysmQ34020340
Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levelsQ34021076
Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysmsQ34074796
Osteopontin: a key cytokine in cell-mediated and granulomatous inflammationQ34216288
Familial abdominal aortic aneurysmsQ34241293
An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levelsQ34262228
A mutation in the gene for type III procollagen (COL3A1) in a family with aortic aneurysmsQ34262977
Pathogenesis of abdominal aortic aneurysmQ34323112
Sequence variant on 9p21 is associated with the presence of abdominal aortic aneurysm disease but does not have an impact on aneurysmal expansionQ34325894
Association of the TGF-beta receptor genes with abdominal aortic aneurysm.Q34328497
The lifetime prevalence of abdominal aortic aneurysms among siblings of aneurysm patients is eightfold higher than among siblings of spouses: an analysis of 187 aneurysm families in Nova Scotia, CanadaQ34374641
Aortic aneurysms: an immune disease with a strong genetic componentQ34402629
Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient miceQ34433103
Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarctionQ34545496
Abdominal aortic aneurysms: basic mechanisms and clinical implicationsQ34555454
Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genesQ34592768
Sequencing of cDNA from 50 unrelated patients reveals that mutations in the triple-helical domain of type III procollagen are an infrequent cause of aortic aneurysmsQ34731356
Binding sites for ETS family of transcription factors dominate the promoter regions of differentially expressed genes in abdominal aortic aneurysmsQ34950585
Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levelsQ35196218
Short leukocyte telomere length is associated with abdominal aortic aneurysm (AAA).Q44528927
Genetic linkage of candidate genes in families with abdominal aortic aneurysms?Q44549103
Human vascular smooth muscle cells possess functional CCR5.Q44837410
Osteoprotegerin and osteopontin are expressed at high concentrations within symptomatic carotid atherosclerosisQ44895972
Clinical and genetic associations in Marfan syndrome and related disordersQ44919578
ACE inhibitors increase type III collagen synthesis: a potential explanation for reduction in acute vascular events by ACE inhibitorsQ44920961
A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrationsQ45245204
Allelic genes involved in artery compliance and susceptibility to sporadic abdominal aortic aneurysmQ45255546
The aneurysm detection and management study screening program: validation cohort and final results. Aneurysm Detection and Management Veterans Affairs Cooperative Study InvestigatorsQ45334593
The pathophysiology of abdominal aortic aneurysm growth: corresponding and discordant inflammatory and proteolytic processes in abdominal aortic and popliteal artery aneurysmsQ45391624
Interaction between angiotensin II, osteoprotegerin, and peroxisome proliferator-activated receptor-gamma in abdominal aortic aneurysmQ46309412
The normotensive carriers of the MTHFR 677T allele, displaying the increased risk of development of the abdominal aortic aneurysm (AAA), occur at the highest frequency among the smoking patientsQ46407260
Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysmQ46477558
Association of osteoprotegerin with human abdominal aortic aneurysm progressionQ46531394
The methylenetetrahydrofolate reductase C677T polymorphism does not associate with susceptibility to abdominal aortic aneurysmQ46582385
The different genotypes of MTHFR 1298A>C and PON1 -108C>T polymorphisms confer the increased risk of the abdominal aortic aneurysm in the smoking and nonsmoking personsQ46979050
The role of the CCR5 Delta32 polymorphism in abdominal aortic aneurysmsQ47708115
Possible association between genetic polymorphisms in transforming growth factor beta receptors, serum transforming growth factor beta1 concentration and abdominal aortic aneurysm.Q47822384
An investigation of polymorphism in the interleukin-10 gene promoterQ48054541
Characterization of a dinucleotide repeat in the 92 kDa type IV collagenase gene (CLG4B), localization of CLG4B to chromosome 20 and the role of CLG4B in aortic aneurysmal diseaseQ48076276
An increased frequency of the 5A allele in the promoter region of the MMP3 gene is associated with abdominal aortic aneurysms.Q50665090
Does the angiotensin-converting enzyme (ACE) gene polymorphism affect rate of abdominal aortic aneurysm expansion?Q50698692
Genetic variation on chromosome 16 is associated with abdominal aortic aneurysm.Q50704621
Genetic risk factor for abdominal aortic aneurysm: HLA-DR2(15), a Japanese study.Q50895981
Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm.Q50917495
Risk factors for abdominal aortic aneurysms in older adults enrolled in The Cardiovascular Health Study.Q51024492
Haptoglobin 2-1 phenotype predicts rapid growth of abdominal aortic aneurysms.Q51147244
Low vitamin B6, and not plasma homocysteine concentration, as risk factor for abdominal aortic aneurysm: a retrospective case-control study.Q51474120
Apolipoprotein E genotype is associated with differential expansion rates of small abdominal aortic aneurysms.Q51555865
Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome.Q52223418
Molecular defects of type III procollagen in Ehlers-Danlos syndrome type IV.Q52828944
Analysis of sequence variations in the ABCC6 gene among patients with abdominal aortic aneurysm and pseudoxanthoma elasticum.Q53845892
eNOS G894T polymorphism and abdominal aortic aneurysms.Q54471596
ACE DD genotype: a predisposing factor for abdominal aortic aneurysm.Q54682070
Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association.Q55051941
Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease ProgressionQ56607621
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysmQ56891289
Genes Predisposing to Rapid Aneurysm GrowthQ56891358
Genotype-phenotype relationships in an investigation of the role of proteases in abdominal aortic aneurysm expansionQ56891425
Influence of type III collagen genotype on aortic diameter and diseaseQ56891769
Selection for screening for familial aortic aneurysmsQ56891849
Genetic variants of collagen III and abdominal aortic aneurysmQ56891862
Association Study of Single Nucleotide Polymorphisms on Chromosome 19q13 With Abdominal Aortic AneurysmQ56893394
The Intracranial Aneurysm Susceptibility Genes HSPG2 and CSPG2 Are Not Associated With Abdominal Aortic AneurysmQ56893407
Matrix Metalloproteinase-2 Gene Variants and Abdominal Aortic AneurysmQ57253631
Polymorphisms of the Interleukin-6 Gene Promoter and Abdominal Aortic AneurysmQ57253671
Association Between Osteopontin and Human Abdominal Aortic AneurysmQ57253686
Functional Polymorphism in the Regulatory Region of Gelatinase B Gene in Relation to Severity of Coronary AtherosclerosisQ57279243
Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic AneurysmQ57316566
Inheritance of an RNA splicing mutation (G+ 1 IVS20) in the type III procollagen gene (COL3A1) in a family having aortic aneurysms and easy bruisability: phenotypic overlap between familial arterial aneurysms and Ehlers-Danlos syndrome type IV.Q35198203
Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE reviewQ35672899
Fibulins in development and heritable diseaseQ35726742
Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection.Q35764050
Expression of heme oxygenase-1 in atherosclerotic lesionsQ35765057
Role of hyperhomocysteinemia in aortic disease.Q36037038
Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activationQ36082965
A human vascular disorder, supravalvular aortic stenosis, maps to chromosome 7.Q36228410
C-reactive protein is produced by a small number of normal human peripheral blood lymphocytesQ36352119
Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient miceQ36524275
Postoperative incision hernia in patients with abdominal aortic aneurysm and aortoiliac occlusive disease: a systematic reviewQ36578175
Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis.Q36962843
Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cellsQ37384330
Inherited diseases and syndromes leading to aortic aneurysms and dissectionsQ37398308
Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohortsQ37415982
Developments in genomics to improve understanding, diagnosis and management of aneurysms and peripheral artery disease.Q37603957
SVS practice guidelines for the care of patients with an abdominal aortic aneurysm: executive summaryQ37604608
Sp1 increases expression of cyclooxygenase-2 in hypoxic vascular endothelium. Implications for the mechanisms of aortic aneurysm and heart failureQ38311997
Gene expression profiling of peripheral blood in patients with abdominal aortic aneurysmQ38510939
Whole genome-expression profiling reveals a role for immune and inflammatory response in abdominal aortic aneurysm rupture.Q38511431
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysemaQ39818948
Novel genetic mechanisms for aortic aneurysmsQ39876021
ACE and TGFBR1 genes interact in influencing the susceptibility to abdominal aortic aneurysmQ40081802
A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levelsQ40561489
Racial differences in the incidence of femoral bypass and abdominal aortic aneurysmectomy in Massachusetts: relationship to cardiovascular risk factors.Q40604544
Identification of genetic variation that determines levels of plasma triglycerides and hypercoagulabilityQ40648445
Interleukin-6 (IL-6) and the prognosis of abdominal aortic aneurysmsQ40706826
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathwayQ40890343
Polymorphisms of the matrix metalloproteinase 9 gene and abdominal aortic aneurysmQ41148674
Local expression of inflammatory cytokines in human atherosclerotic plaquesQ41531228
ECM and cell surface proteolysis: regulating cellular ecologyQ41656253
Transcriptional regulation through cytokine and glucocorticoid response elements of rat acute phase plasma protein genes by C/EBP and JunBQ41660299
Epidemiology of aortic aneurysm repair in the United States from 1993 to 2003.Q42607112
Genetic and environmental contributions to abdominal aortic aneurysm development in a twin populationQ42640800
Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated responseQ42773864
Genome Wide Association Studies: identifying the genes that determine the risk of abdominal aortic aneurysmQ43111346
The genetics of abdominal aortic aneurysms: a comprehensive meta-analysis involving eight candidate genes in over 16,700 patientsQ43123918
Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E(2)-dependent plaque instabilityQ43714032
Matrix metalloproteinase 2 polymorphisms in a caucasian population with abdominal aortic aneurysmQ43805798
Regarding “Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association”Q57445681
Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysmQ57445690
HLA-DQA Is Associated with Abdominal Aortic Aneurysms in the Belgian PopulationQ57783954
Genome Scan for Familial Abdominal Aortic Aneurysm Using Sex and Family History as Covariates Suggests Genetic Heterogeneity and Identifies Linkage to Chromosome 19q13Q57783968
Analysis of coding sequences for tissue inhibitor of metalloproteinases 1 (TIMP1) and 2 (TIMP2) in patients with aneurysmsQ57783985
Multiple Defects in Type III Collagen Synthesis Are Associated with the Pathogenesis of Abdominal Aortic AneurysmsQ57784050
Deletion Polymorphism in the Gene for Angiotensin-converting Enzyme is not a Risk Factor Predisposing to Abdominal Aortic AneurysmQ58363877
Interleukin-1 gene cluster variants and abdominal aortic aneurysmsQ58957922
Heme oxygenase-1 gene promoter polymorphism is associated with abdominal aortic aneurysmQ58959100
eNOS G894T polymorphism as a mild predisposing factor for abdominal aortic aneurysmQ59402976
The cholesteryl ester transfer protein (CETP) locus as a candidate gene in abdominal aortic aneurysmQ60440934
High prevalence of mild hyperhomocysteinemia in patients with abdominal aortic aneurysmQ61480581
Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Polymorphisms in a Caucasian Population with Abdominal Aortic AneurysmQ61773589
Genetic risk factor characterizes abdominal aortic aneurysm from arterial occlusive disease in human beings: CCR5 Δ32 deletionQ61820515
High levels of homocysteine, lipoprotein (a) and plasminogen activator inhibitor-1 are present in patients with abdominal aortic aneurysmQ62607045
Apolipoprotein E polymorphism and atherosclerosisQ68126635
Acute phase proteins in patients with abdominal aortic aneurysmsQ69005397
Endogenous nitric oxide inhibits human platelet adhesion to vascular endotheliumQ69908131
Decreased tissue inhibitor of metalloproteinases (TIMP) in abdominal aortic aneurysm tissue: a preliminary reportQ70191804
Elastolytic and collagenolytic studies of arteries. Implications for the mechanical properties of aneurysmsQ70195438
Blood groups and HLA antigens in patients with abdominal aortic aneurysmsQ70484833
Association between haptoglobin groups and aortic abdominal aneurysmsQ70588783
Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 betaQ70865443
A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase geneQ70908032
Alpha-1-antitrypsin deficiency in aneurysmal diseaseQ71150753
Activated forms of MMP2 and MMP9 in abdominal aortic aneurysmsQ71218618
Quantitative studies on the inherited variants of serum alpha-1-antitrypsinQ71269100
Unravelling the familial tendency to aneurysmal disease: popliteal aneurysm, hypertension and fibrillin genotypeQ71407507
Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysmQ71938798
In situ localization and quantification of seventy-two-kilodalton type IV collagenase in aneurysmal, occlusive, and normal aortaQ72057993
Interleukin-1 beta induces differential gene expression in aortic smooth muscle cellsQ72820997
Expression and sequence of the gene for tissue inhibitor of metalloproteinases in patients with abdominal aortic aneurysmsQ72877288
Elevations of tissue-type plasminogen activator and differential expression of urokinase-type plasminogen activator in diseased aortaQ73025879
A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UKQ73049822
Genetic risk factors in inflammatory abdominal aortic aneurysms: polymorphic residue 70 in the HLA-DR B1 gene as a key genetic elementQ73114784
Negative genetic risk factor for abdominal aortic aneurysm: HLA-DQ3, a Japanese studyQ73153370
The role of cytokine gene polymorphisms in the pathogenesis of abdominal aortic aneurysms: a case-control studyQ73413687
Homocysteine induces synthesis of a serine elastase in arterial smooth muscle cells from multi-organ donorsQ73529910
Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aortaQ73676314
Association of the 4G/5G polymorphism in the promoter region of plasminogen activator inhibitor-1 with abdominal aortic aneurysmsQ73777093
Inflammation, metalloproteinases, and increased proteolysis: an emerging pathophysiological paradigm in aortic aneurysmQ73804291
Role of HLA-DR in the pathogenesis of abdominal aortic aneurysmQ73807413
Genetic analysis on HLA loci in Japanese patients with abdominal aortic aneurysmQ73807415
Abdominal aortic aneurysm in normotensive patients: association with angiotensin-converting enzyme gene polymorphismQ73880919
Allele frequency of human endothelial nitric oxide synthase gene polymorphism in abdominal aortic aneurysmQ73975277
Genetic similarity in inflammatory and degenerative abdominal aortic aneurysms: a study of human leukocyte antigen class II disease risk genesQ74131947
Abdominal aortic aneurysm in womenQ74131996
P433issue3
P304page(s)388-412
P577publication date2010-12-13
P1433published inAnnals of Vascular SurgeryQ15751634
P1476titleGenes and abdominal aortic aneurysm
P478volume25

Reverse relations

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