| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/S0166-2236(02)02157-4 |
| P698 | PubMed publication ID | 12086751 |
| P2093 | author name string | Michael H Ossipov | |
| Frank Porreca | |||
| G F Gebhart | |||
| P433 | issue | 6 | |
| P921 | main subject | chronic pain | Q1088113 |
| P304 | page(s) | 319-325 | |
| P577 | publication date | 2002-06-01 | |
| P1433 | published in | Trends in Neurosciences | Q3538443 |
| P1476 | title | Chronic pain and medullary descending facilitation | |
| P478 | volume | 25 |
| Q35069143 | 2020 Foresight: Envisioning Therapeutic Innovations for Pain |
| Q40349158 | A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins |
| Q47554740 | A Functional Neuroimaging Study of Expectancy Effects on Pain Response in Patients with Knee Osteoarthritis |
| Q47853984 | A brain-based pain facilitation mechanism contributes to painful diabetic polyneuropathy. |
| Q50758640 | A comparison of visceral and somatic pain processing in the human brainstem using functional magnetic resonance imaging. |
| Q41790041 | A life switch in pain |
| Q44805472 | A mapping study of cardiorespiratory responses to chemical stimulation of the midline medulla oblongata in ventilated and freely breathing rats |
| Q42066062 | A possible neural basis for stress-induced hyperalgesia |
| Q37773988 | A review of SSRIs and SNRIs in neuropathic pain |
| Q33578684 | A role of periaqueductal grey NR2B-containing NMDA receptor in mediating persistent inflammatory pain |
| Q35432010 | A role of supraspinal galanin in behavioural hyperalgesia in the rat. |
| Q90594683 | Abnormal alpha band power in the dynamic pain connectome is a marker of chronic pain with a neuropathic component |
| Q37036547 | Acidic buffer induced muscle pain evokes referred pain and mechanical hyperalgesia in humans |
| Q52728066 | Activation of Astrocytes and Microglial Cells and CCL2/CCR2 Upregulation in the Dorsolateral and Ventrolateral Nuclei of Periaqueductal Gray and Rostral Ventromedial Medulla Following Different Types of Sciatic Nerve Injury. |
| Q42030887 | Activation of mitogen-activated protein kinase in descending pain modulatory system |
| Q34959427 | Activation of rostral ventromedial medulla neurons by noxious stimulation of cutaneous and deep craniofacial tissues |
| Q90662239 | Activation of the Intrinsic Pain Inhibitory Circuit from the Midcingulate Cg2 to Zona Incerta Alleviates Neuropathic Pain |
| Q42579973 | Activity of murine raphe magnus cells predicts tachypnea and on-going nociceptive responsiveness. |
| Q64912436 | Acute nociceptive stimuli rapidly induce the activity of serotonin and noradrenalin neurons in the brain stem of awake mice. |
| Q36867757 | Adaptations in responsiveness of brainstem pain-modulating neurons in acute compared with chronic inflammation |
| Q48323276 | Administrations of thalidomide into the rostral ventromedial medulla produce antinociceptive effects in a rat model of postoperative pain. |
| Q36730512 | Alcohol dependence as a chronic pain disorder |
| Q34470172 | Algogenic substances and metabolic status in work-related Trapezius Myalgia: a multivariate explorative study |
| Q53401887 | Altered excitability and local connectivity of mPFC-PAG neurons in a mouse model of neuropathic pain. |
| Q61810559 | Altered glial glutamate transporter expression in descending circuitry and the emergence of pain chronicity |
| Q37360327 | Altered morphine-induced analgesia in neurotensin type 1 receptor null mice. |
| Q36536069 | Altered periaqueductal gray resting state functional connectivity in migraine and the modulation effect of treatment |
| Q42116258 | Altered resting state EEG in chronic pancreatitis patients: toward a marker for chronic pain |
| Q37446314 | Analgesia accompanying food consumption requires ingestion of hedonic foods |
| Q47099589 | Analgesic Mechanisms of Antidepressants for Neuropathic Pain |
| Q44700491 | Anti-hyperalgesic effect of octreotide in patients with irritable bowel syndrome |
| Q46679035 | Anti-nociception is selectively enhanced by parallel inhibition of multiple subtypes of monoamine transporters in rat models of persistent and neuropathic pain |
| Q42409412 | Anti-superoxide and anti-peroxynitrite strategies in pain suppression |
| Q34907407 | Antidepressants for the treatment of chronic pain. |
| Q43069050 | Antinociception induced by chronic glucocorticoid treatment is correlated to local modulation of spinal neurotransmitter content |
| Q64113639 | Astrocyte activation in the periaqueductal gray promotes descending facilitation to cancer-induced bone pain through the JNK MAPK signaling pathway |
| Q49058087 | Aβ and Aδ but not C-fibres are involved in stroke related pain and allodynia: an experimental study in mice. |
| Q37637853 | Blockade of opioid receptors in the medullary reticularis nucleus dorsalis, but not the rostral ventromedial medulla, prevents analgesia produced by diffuse noxious inhibitory control in rats with muscle inflammation |
| Q37193131 | Brain-derived neurotrophic factor-mediated downregulation of brainstem K+-Cl- cotransporter and cell-type-specific GABA impairment for activation of descending pain facilitation |
| Q30490018 | Brainstem control of cerebral blood flow and application to acute vasospasm following experimental subarachnoid hemorrhage. |
| Q31037036 | Brainstem functional imaging in humans. |
| Q30469133 | CNS animal fMRI in pain and analgesia |
| Q33815125 | Can neuroimaging studies identify pain endophenotypes in humans? |
| Q28211527 | Can we conquer pain? |
| Q36096057 | Canadian Association of Neuroscience review: Cellular and synaptic insights into physiological and pathological pain. EJLB-CIHR Michael Smith Chair in Neurosciences and Mental Health lecture. |
| Q36599929 | Cancer pain and its impact on diagnosis, survival and quality of life |
| Q34950501 | Caudal granular insular cortex is sufficient and necessary for the long-term maintenance of allodynic behavior in the rat attributable to mononeuropathy |
| Q35904210 | Cell signaling and the genesis of neuropathic pain |
| Q90287692 | Cell type-specific modulation of sensory and affective components of itch in the periaqueductal gray |
| Q29011961 | Cellular and Molecular Mechanisms of Pain |
| Q41431822 | Central Sensitization-Based Classification for Temporomandibular Disorders: A Pathogenetic Hypothesis |
| Q36389280 | Central amygdala metabotropic glutamate receptor 5 in the modulation of visceral pain |
| Q37800357 | Central mechanisms of pathological pain |
| Q24604236 | Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders |
| Q48659117 | Cerebral mechanisms of experimental hyperalgesia in fibromyalgia. |
| Q34134834 | Cerebral responses to innocuous somatic pressure stimulation following aerobic exercise rehabilitation in chronic pain patients: a functional magnetic resonance imaging study |
| Q37645676 | Challenges and opportunities in pain management disparities research: implications for clinical practice, advocacy, and policy |
| Q33947001 | Challenges in the development of novel treatment strategies for neuropathic pain |
| Q47246759 | Changes in microRNA expression in the brachial plexus avulsion model of neuropathic pain |
| Q36399772 | Changes in response properties of rostral ventromedial medulla neurons during prolonged inflammation: modulation by neurokinin-1 receptors |
| Q58251673 | Chapter 13 Descending inhibitory systems |
| Q82028755 | Chapter 14 Descending excitatory systems |
| Q82028789 | Chapter 20 Central sensitization following nerve injury: molecular mechanisms |
| Q82028794 | Chapter 21 Pain following spinal cord injury: central mechanisms |
| Q82028694 | Chapter 7 Pain and the spinal cord |
| Q39906178 | Chapter 9 The dorsal horn and hyperalgesia |
| Q37586037 | Chemokine signaling involving chemokine (C-C motif) ligand 2 plays a role in descending pain facilitation |
| Q37684327 | Chemokines, neuronal-glial interactions, and central processing of neuropathic pain |
| Q93164801 | Chloride - The Underrated Ion in Nociceptors |
| Q33774088 | Chronic musculoskeletal pain: review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique |
| Q36772936 | Chronic neuropathic pain: mechanisms, drug targets and measurement |
| Q37887005 | Chronic pain and surgery: a review of new insights from sensory testing |
| Q37237857 | Classification of low back-related leg pain: do subgroups differ in disability and psychosocial factors? |
| Q44338316 | Coexpression of the mu-opioid receptor splice variant MOR1C and the vesicular glutamate transporter 2 (VGLUT2) in rat central nervous system |
| Q27007091 | Cognitive and emotional control of pain and its disruption in chronic pain |
| Q37963569 | Combination therapy for neuropathic pain: a review of current evidence |
| Q39307501 | Comparative Pre-Emptive Analgesic Efficacy Study of Novel Antiepileptic Agents Lamotrigine and Topiramate in Patients Undergoing Major Surgeries at a Tertiary Care Hospital: A Randomized Double Blind Clinical Trial |
| Q30427741 | Comparison of anterior cingulate vs. insular cortex as targets for real-time fMRI regulation during pain stimulation |
| Q37392010 | Corneal pain without stain: is it real? |
| Q88730755 | Corticotropin-Releasing Factor in the Brain and Blocking Spinal Descending Signals Induce Hyperalgesia in the Latent Sensitization Model of Chronic Pain |
| Q35178781 | Current insights into the pathophysiology of irritable bowel syndrome |
| Q60061936 | Cyclooxygenase-1-Derived Prostaglandins in the Periaqueductal Gray Differentially Control C- versus A-Fiber-Evoked Spinal Nociception |
| Q48878707 | Decrease in the expression of N-methyl-D-aspartate receptors in the nucleus tractus solitarii induces antinociception and increases blood pressure. |
| Q46953284 | Depletion of capsaicin-sensitive afferents prevents lamina-dependent increases in spinal N-methyl-D-aspartate receptor subunit 1 expression and phosphorylation associated with thermal hyperalgesia in neuropathic rats |
| Q48598071 | Depression, anxiety, health-related quality of life and pain in patients with chronic fibromyalgia and neuropathic pain. |
| Q24624664 | Descending control of nociception: Specificity, recruitment and plasticity |
| Q39192412 | Descending facilitation |
| Q36844467 | Descending facilitatory pathways from the RVM initiate and maintain bilateral hyperalgesia after muscle insult |
| Q33640293 | Descending facilitatory pathways from the rostroventromedial medulla mediate naloxone-precipitated withdrawal in morphine-dependent rats |
| Q47776764 | Descending mechanisms activated by the anterior pretectal nucleus initiate but do not maintain neuropathic pain in rats. |
| Q42953386 | Descending serotonergic controls regulate inflammation-induced mechanical sensitivity and methyl-CpG-binding protein 2 phosphorylation in the rat superficial dorsal horn |
| Q42556628 | Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain |
| Q41892811 | Descending serotonergic facilitation of spinal ERK activation and pain behavior |
| Q37107478 | Development of the serotonergic cells in murine raphe nuclei and their relations with rhombomeric domains |
| Q48648568 | Diagnosis and management of trigeminal neuropathic pains. |
| Q38206072 | Diagnosis and treatment of narcotic bowel syndrome |
| Q34217686 | Diencephalic and brainstem mechanisms in migraine |
| Q47433710 | Different Brain Circuitries Mediating Controllable and Uncontrollable Pain. |
| Q47935439 | Different pain responses to chronic and acute pain in various ethnic/racial groups |
| Q45064288 | Differential corticomotor control of a muscle adjacent to a painful joint |
| Q41902234 | Differential effects of voltage-gated calcium channel blockers on calcium channel alpha-2-delta-1 subunit protein-mediated nociception |
| Q33400940 | Differential endogenous pain modulation in complex-regional pain syndrome |
| Q35787565 | Differential modulation of neurons in the rostral ventromedial medulla by neurokinin-1 receptors. |
| Q42953652 | Differential responding of autonomic function to histamine H1 antagonism in irritable bowel syndrome |
| Q36384322 | Disambiguating Pharmacodynamic Efficacy from Behavior with Neuroimaging: Implications for Analgesic Drug Development |
| Q30895151 | Discharge of raphe magnus ON and OFF cells is predictive of the motor facilitation evoked by repeated laser stimulation. |
| Q53690404 | Distinct mechanisms underlying pronociceptive effects of opioids. |
| Q41338045 | Distinct pathways for norepinephrine- and opioid-triggered antinociception from the amygdala |
| Q39215737 | Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena |
| Q43017137 | Dopaminergic D2 receptors activate PKA to inhibit spinal pelvic-urethra reflex in rats |
| Q37500352 | Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B. |
| Q48826263 | Dorsal striatum metabotropic glutamate receptor 8 affects nocifensive responses and rostral ventromedial medulla cell activity in neuropathic pain conditions. |
| Q40147058 | EP1 receptor within the ventrolateral periaqueductal grey controls thermonociception and rostral ventromedial medulla cell activity in healthy and neuropathic rat. |
| Q30583130 | Effect of hypnotherapy and educational intervention on brain response to visceral stimulus in the irritable bowel syndrome |
| Q52668421 | Effects of Transcranial Direct Current Stimulation Block Remifentanil-Induced Hyperalgesia: A Randomized, Double-Blind Clinical Trial. |
| Q48433166 | Effects of a cannabinoid agonist on spinal nociceptive neurons in a rodent model of neuropathic pain. |
| Q37355350 | Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat. |
| Q37777216 | Effects of antidepressants in patients with irritable bowel syndrome and comorbid depression |
| Q49384757 | Efficient conditioned pain modulation despite pain persistence in painful diabetic neuropathy. |
| Q48189512 | Electroacupuncture Inhibits the Activation of p38MAPK in the Central Descending Facilitatory Pathway in Rats with Inflammatory Pain. |
| Q46843607 | Electrophysiological heterogeneity of spinally projecting serotonergic and nonserotonergic neurons in the rostral ventromedial medulla |
| Q30435830 | Emotional modulation of pain and spinal nociception in fibromyalgia |
| Q38250226 | Endogenous analgesia, dependence, and latent pain sensitization |
| Q35581558 | Endogenous opiates and behavior: 2002 |
| Q36178615 | Endogenous opioids inhibit early-stage pancreatic pain in a mouse model of pancreatic cancer |
| Q36787483 | Endothelin-1-induced priming to capsaicin in young animals |
| Q35567536 | Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain |
| Q44580807 | Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation. |
| Q27023688 | Epigenetic mechanisms of chronic pain |
| Q35535806 | Epigenetic suppression of GAD65 expression mediates persistent pain |
| Q37915359 | Evidence for shared pain mechanisms in osteoarthritis, low back pain, and fibromyalgia |
| Q37638967 | Exercise-induced pain requires NMDA receptor activation in the medullary raphe nuclei |
| Q37318776 | Experimental muscle pain impairs descending inhibition |
| Q47605456 | Expression of aromatase in the rostral ventromedial medulla and its role in the regulation of visceral pain |
| Q46827799 | Extracellular signal-regulated kinase activation in the chronic constriction injury model of neuropathic pain in anaesthetized rats |
| Q38668534 | Extracellular signal-regulated kinase activation in the spinal cord contributes to visceral hypersensitivity induced by craniofacial injury followed by stress. |
| Q33625406 | Fatiguing exercise enhances hyperalgesia to muscle inflammation |
| Q61443362 | Focus on current and future management possibilities in inflammatory bowel disease-related chronic pain |
| Q37810678 | From descending pain modulation to obesity via the medullary raphe |
| Q36861028 | From neuroanatomy to gene therapy: searching for new ways to manipulate the supraspinal endogenous pain modulatory system. |
| Q42409125 | Functional characterization of a mouse model for central post-stroke pain |
| Q28567229 | GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence |
| Q90838852 | Gainfully employing descending controls in acute and chronic pain management |
| Q35840845 | Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways |
| Q36535900 | Genetic enhancement of neuropathic and inflammatory pain by forebrain upregulation of CREB-mediated transcription |
| Q37100026 | Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits |
| Q42858321 | Getting the pain you expect: mechanisms of placebo, nocebo and reappraisal effects in humans |
| Q37381399 | Glia and pain: is chronic pain a gliopathy? |
| Q45926508 | Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity. |
| Q35489433 | Gynecologic management of neuropathic pain. |
| Q38233014 | Headache and sleep: shared pathophysiological mechanisms. |
| Q48822210 | How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? |
| Q53118365 | Hyperalgesia and sensitization of dorsal horn neurons following activation of NK-1 receptors in the rostral ventromedial medulla. |
| Q39608585 | Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain. |
| Q38817592 | Imaging Acute and Chronic Pain in the Human Brainstem and Spinal Cord. |
| Q37346885 | Imaging CNS modulation of pain in humans |
| Q34588877 | Immediate changes after manual therapy in resting-state functional connectivity as measured by functional magnetic resonance imaging in participants with induced low back pain |
| Q35915891 | Importance of anti- and pro-nociceptive mechanisms in human disease |
| Q42081407 | Increased abundance of opioid receptor heteromers after chronic morphine administration |
| Q28299823 | Increased feelings with increased body signals |
| Q37260551 | Increased glutamate and decreased glycine release in the rostral ventromedial medulla during induction of a pre-clinical model of chronic widespread muscle pain |
| Q24806600 | Increased glutamate synaptic transmission in the nucleus raphe magnus neurons from morphine-tolerant rats |
| Q37785552 | Influence of trigger factors on the efficacy of almotriptan as early intervention for the treatment of acute migraine in a primary care setting: the START study |
| Q83973731 | Inhibition of glial activation in rostral ventromedial medulla attenuates mechanical allodynia in a rat model of cancer-induced bone pain |
| Q35689133 | Inhibition of temporomandibular joint input to medullary dorsal horn neurons by 5HT3 receptor antagonist in female rats. |
| Q41772718 | Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina I projection pathway |
| Q37227196 | Inputs to serotonergic neurons revealed by conditional viral transneuronal tracing |
| Q33823524 | Intrinsic functional connectivity of the periaqueductal gray, a resting fMRI study |
| Q33775263 | Investigation of Molecular Mechanism of Chronic Pain in the Anterior Cingulate Cortex Using Genetically Engineered Mice |
| Q36453054 | Investigation of brainstem: descending pain modulation in animals and humans. |
| Q36798029 | Is blood glucose associated with descending modulation of spinal nociception as measured by the nociceptive flexion reflex? |
| Q37794850 | Is it all central sensitization? Role of peripheral tissue nociception in chronic musculoskeletal pain |
| Q28387989 | Is neuroplasticity in the central nervous system the missing link to our understanding of chronic musculoskeletal disorders? |
| Q28583215 | Kappa opioid receptors in the rostral ventromedial medulla of male and female rats |
| Q34147049 | Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat. |
| Q41820712 | Laminar organization of spinal dorsal horn neurones activated by C- vs. A-heat nociceptors and their descending control from the periaqueductal grey in the rat |
| Q34333206 | Levels of neuropeptide Y in synovial fluid relate to pain in patients with knee osteoarthritis |
| Q42702528 | Long-lasting oral analgesic effects of N-protected aminophosphinic dual ENKephalinase inhibitors (DENKIs) in peripherally controlled pain |
| Q42596486 | Loss of neurons in rostral ventromedial medulla that express neurokinin-1 receptors decreases the development of hyperalgesia |
| Q36767144 | Management of neuropathic orofacial pain |
| Q37980743 | Managing pain in inflammatory bowel disease. |
| Q52097483 | Mechanisms of craniofacial pain. |
| Q36577250 | Mechanisms of disease: mechanism-based classification of neuropathic pain-a critical analysis |
| Q36728934 | Mechanisms of hypersensitivity in IBS and functional disorders |
| Q57805519 | Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray |
| Q37409407 | Medullary pain facilitating neurons mediate allodynia in headache-related pain |
| Q46911565 | Medullary raphe neurons facilitate brown adipose tissue activation. |
| Q33992618 | Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial |
| Q39383011 | Mental stress inhibits pain perception and heart rate variability but not a nociceptive withdrawal reflex |
| Q46351143 | Microinjection of morphine into thalamic nucleus submedius depresses bee venom-induced inflammatory pain in the rat. |
| Q38124642 | Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain |
| Q36505033 | Molecular Docking Studies of Phytocompounds from the Phyllanthus Species as Potential Chronic Pain Modulators |
| Q41856863 | Molecular depletion of descending serotonin unmasks its novel facilitatory role in the development of persistent pain |
| Q26770789 | Motor Imagery and Its Effect on Complex Regional Pain Syndrome: An Integrative Review |
| Q28207525 | Multiple actions of systemic artemin in experimental neuropathy |
| Q36972856 | Multiplicative interactions to enhance gabapentin to treat neuropathic pain |
| Q48331306 | NK-1 receptors modulate the excitability of ON cells in the rostral ventromedial medulla |
| Q41939667 | NMDA receptor-mediated activation of medullary pro-nociceptive neurons is required for secondary thermal hyperalgesia |
| Q33640234 | Nerve injury-induced tactile allodynia is present in the absence of FOS labeling in retrogradely labeled post-synaptic dorsal column neurons |
| Q44902293 | Neural basis for the hyperalgesic action of cholecystokinin in the rostral ventromedial medulla |
| Q48409747 | Neural substrate of depression during migraine. |
| Q57990424 | Neural-glial interaction in the spinal cord for the development and maintenance of nerve injury-induced neuropathic pain |
| Q37627512 | Neurobiological Mechanism of Acupuncture for Relieving Visceral Pain of Gastrointestinal Origin |
| Q35669694 | Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain |
| Q36842003 | Neuronal mechanism for neuropathic pain |
| Q26799409 | Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects |
| Q38058412 | Neuropathic mechanisms in the pathophysiology of burns pruritus: redefining directions for therapy and research |
| Q24653841 | Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors |
| Q33925526 | Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression |
| Q55504104 | Neuropathic pain-induced enhancement of spontaneous and pain-evoked neuronal activity in the periaqueductal gray that is attenuated by gabapentin. |
| Q24553796 | Neuropathic pain: a practical guide for the clinician |
| Q92501438 | Neuropeptide S-initiated sequential cascade mediated by OX1, NK1, mGlu5 and CB1 receptors: a pivotal role in stress-induced analgesia |
| Q39784961 | Neuropeptide Y acts at Y1 receptors in the rostral ventral medulla to inhibit neuropathic pain |
| Q39026861 | Neurotensin-produced antinociception in the rostral ventromedial medulla is partially mediated by spinal cord norepinephrine |
| Q35140851 | Neurotrophic factors as novel therapeutics for neuropathic pain |
| Q46819182 | Non-linear morphine-induced depression of spinal excitation following long-term potentiation of C fibre-evoked spinal field potentials. |
| Q37680974 | Nonpharmacological Interventions in Targeting Pain-Related Brain Plasticity |
| Q42261337 | Noradrenergic neurons in the locus coeruleus contribute to neuropathic pain |
| Q35226208 | Notch signaling activation is critical to the development of neuropathic pain |
| Q35000586 | Nucleus accumbens facilitates nociception |
| Q38087443 | Omega-conotoxins as experimental tools and therapeutics in pain management |
| Q27004306 | Opioid receptor heteromers in analgesia |
| Q37117473 | Opioids disrupt pro-nociceptive modulation mediated by raphe magnus |
| Q34586770 | Optogenetic activation of brainstem serotonergic neurons induces persistent pain sensitization |
| Q35369442 | Orexin-a modulates firing of rat rostral ventromedial medulla neurons: an in vitro study |
| Q34987743 | Origin of pain in migraine: evidence for peripheral sensitisation |
| Q36822305 | Pain as a stressor: effects of prior nociceptive stimulation on escape responding of rats to thermal stimulation |
| Q36961163 | Pain facilitation and activity-dependent plasticity in pain modulatory circuitry: role of BDNF-TrkB signaling and NMDA receptors |
| Q34147489 | Pain imaging in health and disease--how far have we come? |
| Q30820200 | Pain imaging: future applications to integrative clinical and basic neurobiology |
| Q39374230 | Pain in ankylosing spondylitis: a neuro-immune collaboration. |
| Q88651332 | Painful stimulation of a sensitized site in the forearm inhibits ipsilateral trigeminal nociceptive blink reflexes |
| Q34212776 | Pains, gains, and midbrains |
| Q39362466 | Parabrachial complex links pain transmission to descending pain modulation |
| Q39127073 | Pathophysiology of Migraine: A Disorder of Sensory Processing |
| Q52094238 | Perceptual correlates of nociceptive long-term potentiation and long-term depression in humans. |
| Q34559323 | Periaqueductal grey cyclooxygenase-dependent facilitation of C-nociceptive drive and encoding in dorsal horn neurons in the rat. |
| Q33593324 | Permanent lesion in rostral ventromedial medulla potentiates swim stress-induced analgesia in formalin test |
| Q34070415 | Persistent inflammation-induced up-regulation of brain-derived neurotrophic factor (BDNF) promotes synaptic delivery of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor GluA1 subunits in descending pain modulatory circuits |
| Q81607534 | Persistent monoarthritis of the temporomandibular joint region enhances nocifensive behavior and lumbar spinal Fos expression after noxious stimulation to the hindpaw in rats |
| Q34193899 | Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans |
| Q42170116 | Phosphorylation of CREB and mechanical hyperalgesia is reversed by blockade of the cAMP pathway in a time-dependent manner after repeated intramuscular acid injections. |
| Q46713280 | Placebo and nocebo: how to enhance therapies and avoid unintended sabotage to pain treatment |
| Q33936661 | Possible Loss of GABAergic Inhibition in Mice With Induced Adenomyosis and Treatment With Epigallocatechin-3-Gallate Attenuates the Loss With Improved Hyperalgesia |
| Q33768262 | Postsynaptic potentiation of corticospinal projecting neurons in the anterior cingulate cortex after nerve injury |
| Q47607719 | Pre-emptive analgesia and its supraspinal mechanisms: enhanced descending inhibition and decreased descending facilitation by dexmedetomidine |
| Q44589947 | Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C |
| Q38840527 | Pregabalin modulation of spinal and brainstem visceral nociceptive processing. |
| Q37612953 | Presynaptic and postsynaptic cortical mechanisms of chronic pain |
| Q44342551 | Presynaptic mechanism for anti-analgesic and anti-hyperalgesic actions of kappa-opioid receptors. |
| Q84626788 | Progesterone Prevents Allodynia After Experimental Spinal Cord Injury |
| Q37620197 | Psychological processing in chronic pain: a neural systems approach. |
| Q37652032 | Quantifying cerebral contributions to pain beyond nociception |
| Q48439171 | Raphe magnus neurons help protect reactions to visceral pain from interruption by cutaneous pain. |
| Q35752366 | Rapid treatment-induced brain changes in pediatric CRPS. |
| Q37765512 | Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain |
| Q34194629 | Real-time fMRI applied to pain management |
| Q50096177 | Reduced cold pressor pain tolerance in non-recovered whiplash patients: a 1-year prospective study. |
| Q47133674 | Regional knockdown of NDUFS4 implicates a thalamocortical circuit mediating anesthetic sensitivity. |
| Q36737749 | Regular physical activity prevents development of chronic pain and activation of central neurons |
| Q35009932 | Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model |
| Q46541961 | Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia |
| Q50847425 | Resting Functional Connectivity of the Periaqueductal Gray Is Associated With Normal Inhibition and Pathological Facilitation in Conditioned Pain Modulation. |
| Q44589954 | Reversal of experimental neuropathic pain by T-type calcium channel blockers |
| Q36583822 | Review article: modulation of the brain-gut axis as a therapeutic approach in gastrointestinal disease |
| Q30410140 | Review of overlap between thermoregulation and pain modulation in fibromyalgia |
| Q34993445 | Reward and motivation in pain and pain relief |
| Q48762186 | Role for medullary pain facilitating neurons in secondary thermal hyperalgesia. |
| Q44919554 | Role for raphe magnus neuronal responses in the behavioral reactions to colorectal distension |
| Q34545402 | Role of NK-1 neurotransmission in opioid-induced hyperalgesia |
| Q89493853 | Role of Spinal Cord α2-Adrenoreceptors in Noradrenergic Inhibition of Nociceptive Transmission During Chemotherapy-Induced Peripheral Neuropathy |
| Q36336640 | Role of brainstem serotonin in analgesia produced by low-intensity exercise on neuropathic pain after sciatic nerve injury in mice |
| Q30436560 | Role of voltage-gated calcium channels in ascending pain pathways |
| Q44342673 | Roles of alpha1- and alpha2-adrenoceptors in the nucleus raphe magnus in opioid analgesia and opioid abstinence-induced hyperalgesia. |
| Q37833285 | Roles of reactive oxygen and nitrogen species in pain |
| Q26751211 | Sensitization and Interoception as Key Neurological Concepts in Osteopathy and Other Manual Medicines |
| Q42638184 | Sensitization of pain-modulating neurons in the rostral ventromedial medulla after peripheral nerve injury. |
| Q30465785 | Sensitization of the trigeminovascular pathway: perspective and implications to migraine pathophysiology |
| Q36639098 | Serotonin enhances urinary bladder nociceptive processing via a 5-HT3 receptor mechanism |
| Q34239382 | Sex similarities and differences in pain-related periaqueductal gray connectivity |
| Q44346545 | Short-duration physical activity prevents the development of activity-induced hyperalgesia through opioid and serotoninergic mechanisms |
| Q39158236 | Sigma-1 Receptor Antagonists: A New Class of Neuromodulatory Analgesics |
| Q84538458 | Sleep and headache |
| Q41452894 | Spatial and temporal plasticity of synaptic organization in anterior cingulate cortex following peripheral inflammatory pain: multi-electrode array recordings in rats |
| Q44485367 | Spatially defined modulation of skin temperature and hand ownership of both hands in patients with unilateral complex regional pain syndrome |
| Q38793076 | Spinal 5-HT(3) receptor activation induces behavioral hypersensitivity via a neuronal-glial-neuronal signaling cascade |
| Q41041620 | Spinal 5-HT3 receptors mediate descending facilitation and contribute to behavioral hypersensitivity via a reciprocal neuron-glial signaling cascade |
| Q24624781 | Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla |
| Q48321717 | Spinal cord plasticity and acid-sensing ion channels involvement in a rodent model of irritable bowel syndrome. |
| Q48284771 | Spinal cord-midbrain functional connectivity is related to perceived pain intensity: a combined spino-cortical FMRI study |
| Q37490257 | Spinal inhibitory neurotransmission in neuropathic pain |
| Q44483313 | Spinal neuronal responses to urinary bladder stimulation in rats with corticosterone or aldosterone onto the amygdala |
| Q28571695 | Spinal pharmacology of antinociception produced by microinjection of mu or delta opioid receptor agonists in the ventromedial medulla of the rat |
| Q35811910 | State-dependent opioid control of pain |
| Q28388747 | Stress enhances muscle nociceptor activity in the rat |
| Q37298857 | Substance P enhances excitatory synaptic transmission on spinally projecting neurons in the rostral ventromedial medulla after inflammatory injury |
| Q46884566 | Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation. |
| Q41945316 | Supraspinal glial-neuronal interactions contribute to descending pain facilitation |
| Q90215320 | Supraspinal interaction between HIV-1-gp120 and cannabinoid analgesic effectiveness |
| Q49937432 | Supraspinal modulation of neuronal synchronization by nociceptive stimulation induces an enduring reorganization of dorsal horn neuronal connectivity. |
| Q36439007 | Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway |
| Q42524394 | Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers. |
| Q35226089 | Sustained morphine-induced sensitization and loss of diffuse noxious inhibitory controls in dura-sensitive medullary dorsal horn neurons |
| Q42371306 | TRPV1 in pain control from the brain |
| Q37057494 | TRPV1-mediated presynaptic transmission in basolateral amygdala contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation |
| Q30501239 | Targeting chronic and neuropathic pain: the N-type calcium channel comes of age. |
| Q37421849 | Tet1-dependent epigenetic modification of BDNF expression in dorsal horn neurons mediates neuropathic pain in rats |
| Q93186053 | The Involvement of Descending Pain Inhibitory System in Electroacupuncture-Induced Analgesia |
| Q35897858 | The Lysophosphatidylinositol Receptor GPR55 Modulates Pain Perception in the Periaqueductal Gray |
| Q35779153 | The amygdala and persistent pain |
| Q46984799 | The antipsychotic drug, fluphenazine, effectively reverses mechanical allodynia in rat models of neuropathic pain |
| Q37280260 | The brain-gut axis in abdominal pain syndromes |
| Q92167370 | The central nucleus of the amygdala lesion attenuates orthodontic pain during experimental tooth movement in rats |
| Q35205451 | The challenge of chronic pain |
| Q36802455 | The dorsomedial hypothalamus mediates stress-induced hyperalgesia and is the source of the pronociceptive peptide cholecystokinin in the rostral ventromedial medulla |
| Q35774936 | The effect of heterotopic noxious conditioning stimulation on Aδ-, C- and Aβ-fibre brain responses in humans |
| Q30452240 | The enigma of the dorsolateral pons as a migraine generator |
| Q38248064 | The narcotic bowel syndrome: a recent update |
| Q36136622 | The narcotic bowel syndrome: clinical features, pathophysiology, and management |
| Q38531270 | The neuroscience of placebo effects: connecting context, learning and health |
| Q38816410 | The noradrenergic locus coeruleus as a chronic pain generator |
| Q36017673 | The pain imaging revolution: advancing pain into the 21st century |
| Q38640212 | The risk for problematic opioid use in chronic pain: What can we learn from studies of pain and reward? |
| Q38439654 | The role of sleep in pain and fibromyalgia |
| Q35669362 | The role of trigeminal interpolaris-caudalis transition zone in persistent orofacial pain |
| Q37692170 | The selectivity of rostroventral medulla descending control of spinal sensory inputs shifts postnatally from A fibre to C fibre evoked activity |
| Q38035093 | The transition from acute to chronic pain: might intensive care unit patients be at risk? |
| Q48262469 | The ventral portion of the anterior pretectal nucleus controls descending mechanisms that initiate neuropathic pain in rats. |
| Q38106491 | Therapeutic time window of noninvasive brain stimulation for pain treatment: inhibition of maladaptive plasticity with early intervention |
| Q44037083 | Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain. |
| Q35123770 | Tolerance effects of non-steroidal anti-inflammatory drugs microinjected into central amygdala, periaqueductal grey, and nucleus raphe: Possible cellular mechanism. |
| Q55190589 | Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex. |
| Q36807025 | Transition to persistent orofacial pain after nerve injury involves supraspinal serotonin mechanisms |
| Q37505177 | Translating nociceptor sensitivity: the role of axonal protein synthesis in nociceptor physiology |
| Q46817289 | Trigeminal transition zone/rostral ventromedial medulla connections and facilitation of orofacial hyperalgesia after masseter inflammation in rats |
| Q36356367 | Trigeminal-rostral ventromedial medulla circuitry is involved in orofacial hyperalgesia contralateral to tissue injury |
| Q36301292 | Unitary hypothesis for multiple triggers of the pain and strain of migraine |
| Q33566804 | Unravelling the mystery of pain, suffering, and relief with brain imaging |
| Q37807929 | Update on medication-overuse headache |
| Q43139081 | Visceral analgesic effect of 5-HT(4) receptor agonist in rats involves the rostroventral medulla (RVM). |
| Q57466905 | Why mu-opioid agonists have less analgesic efficacy in neuropathic pain? |
| Q33750230 | Widespread hyperalgesia in irritable bowel syndrome is dynamically maintained by tonic visceral impulse input and placebo/nocebo factors: evidence from human psychophysics, animal models, and neuroimaging |
| Q56984196 | [EXPRESS] The multimodal antidepressant vortioxetine causes analgesia in a mouse model of chronic neuropathic pain |
| Q82908447 | [Pain and bone metastases] |
| Q44348673 | cAMP-mediated mechanisms for pain sensitization during opioid withdrawal. |
| Q48488806 | fMRI reveals distinct CNS processing during symptomatic and recovered complex regional pain syndrome in children. |
| Q36345136 | p38 MAPK, microglial signaling, and neuropathic pain |
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