Even low-level HER2 expression may be associated with worse outcome in node-positive breast cancer

scientific article

Even low-level HER2 expression may be associated with worse outcome in node-positive breast cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1097/PAS.0B013E31819437F9
P932PMC publication ID3063383
P698PubMed publication ID19252432
P5875ResearchGate publication ID24146961

P50authorGreg N. FullerQ37370656
Francisco J EstevaQ43937223
Wendy A WoodwardQ61037731
P2093author name stringThomas A Buchholz
Susan L Tucker
Michael Z Gilcrease
Marlo M Nicolas
Lynda J Corley
P2860cites workUse of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.Q27824766
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study groupQ27824835
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancerQ27824847
Lapatinib plus capecitabine for HER2-positive advanced breast cancerQ27851403
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogeneQ27860693
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancerQ29547699
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancerQ29616112
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancerQ29617440
2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical OncologyQ34184177
Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancerQ34496969
HER2 expression and efficacy of dose-dense anthracycline-containing adjuvant chemotherapy in breast cancer patientsQ36614830
Overexpression of c-erbB2 is an independent marker of resistance to endocrine therapy in advanced breast cancerQ36617556
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancerQ36678853
HER2 overexpression and doxorubicin in adjuvant chemotherapy for resectable breast cancer.Q38453585
Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): a study of incidence and correlation with outcome in breast cancerQ38463900
Analysis of c-erbB-2 expression in breast carcinomas with clinical follow-upQ38490688
Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-2 protein overexpression in primary breast cancerQ41756399
HER-2/neu oncogene protein and prognosis in breast cancerQ41927421
Chemotherapy response of breast cancer depends on HER-2 status and anthracycline dose intensity in the neoadjuvant setting.Q43643447
A phase III trial of sequential adjuvant chemotherapy for operable breast carcinoma: final analysis with 10-year follow-upQ44454004
Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancerQ44927602
Comparison of HER2 status by fluorescence in situ hybridization and immunohistochemistry to predict benefit from dose escalation of adjuvant doxorubicin-based therapy in node-positive breast cancer patientsQ46580491
Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly scheduleQ50773376
Evaluation of the United States Food and Drug Administration-approved scoring and test system of HER-2 protein expression in breast cancerQ59616875
HER-2/neu amplification predicts poor survival in node-positive breast cancerQ68091225
Prognostic significance of c-erbB-2 and estrogen receptor status in human breast cancerQ68301337
c-erb B2 overexpression decreases the benefit of adjuvant tamoxifen in early-stage breast cancer without axillary lymph node metastasesQ71692738
Prognostic significance of HER-2/neu oncoprotein expression in node-positive breast cancer. The influence of the pattern of immunostaining and adjuvant therapyQ72675847
Quantitative analysis of breast cancer tissue microarrays shows that both high and normal levels of HER2 expression are associated with poor outcomeQ73205060
erbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancerQ77331949
erbB-2 and response to doxorubicin in patients with axillary lymph node-positive, hormone receptor-negative breast cancerQ77331953
Inconsistency of HER2 test raises questionsQ80595700
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)759-767
P577publication date2009-05-01
P1433published inThe American Journal of Surgical PathologyQ7713508
P1476titleEven low-level HER2 expression may be associated with worse outcome in node-positive breast cancer
P478volume33

Reverse relations

cites work (P2860)
Q60044026BCL-2 expression aids in the immunohistochemical prediction of the Oncotype DX breast cancer recurrence score
Q58786250Clinical and prognostic profile of Her2neu positive (non-luminal) intrinsic breast cancer subtype: comparison with Her2neu positive luminal breast cancers
Q37613953Clinical impact of delaying initiation of adjuvant chemotherapy in patients with breast cancer
Q40951473Cyclin E amplification, over-expression, and relapse-free survival in HER-2-positive primary breast cancer
Q24810389ERBB2 in cat mammary neoplasias disclosed a positive correlation between RNA and protein low expression levels: a model for erbB-2 negative human breast cancer
Q34133760ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis
Q38832170Expression analysis of four long noncoding RNAs in breast cancer
Q34981712HER2 as a promising target for cytotoxicity T cells in human melanoma therapy
Q37317064Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism
Q44541840Impact of estrogen receptor (ER) and human epidermal growth factor receptor-2 (HER2) co-expression on breast cancer disease characteristics: implications for tumor biology and research
Q64115873Introduction to Digital Image Analysis in Whole-slide Imaging: A White Paper from the Digital Pathology Association
Q36405652Moderate immunohistochemical expression of HER-2 (2+) without HER-2 gene amplification is a negative prognostic factor in early breast cancer
Q53523972Moderate level of HER2 expression and its prognostic significance in breast cancer with intermediate grade.
Q40453735Prognostic significance of equivocal human epidermal growth factor receptor 2 results and clinical utility of alternative chromosome 17 genes in patients with invasive breast cancer: A cohort study.
Q33862786Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update
Q37993442Role of HER2-neu as a prognostic factor for survival and relapse in pT1a-bN0M0 breast cancer: a systematic review of the literature with a pooled-analysis
Q34424285Testing for HER2 in Breast Cancer: A Continuing Evolution
Q35201328The significance of HER-2/neu receptor positivity and immunophenotype in ductal carcinoma in situ with early invasive disease
Q54676467[Her2 testing in gastric cancer. What is different in comparison to breast cancer?].

Search more.