scholarly article | Q13442814 |
P2093 | author name string | Yu Peng | |
Andrew D Napper | |||
Katherine M Drake | |||
Venita Gresham Watson | |||
P2860 | cites work | The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling | Q40202913 |
The synthetic peptide PFWT disrupts AF4-AF9 protein complexes and induces apoptosis in t(4;11) leukemia cells | Q40532537 | ||
New insights to the MLL recombinome of acute leukemias | Q44945193 | ||
The MLL recombinome of acute leukemias | Q56965972 | ||
An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners | Q74060943 | ||
Rational design of the first small-molecule antagonists of NHERF1/EBP50 PDZ domains | Q80459449 | ||
The minimum significant ratio: a statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies | Q82615309 | ||
Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. | Q27675570 | ||
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays | Q28145712 | ||
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability | Q29547634 | ||
New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays | Q29615588 | ||
BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets | Q33864494 | ||
MLL fusion partners AF4 and AF9 interact at subnuclear foci | Q34275143 | ||
MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia | Q34571591 | ||
MLL-rearranged leukemias: insights from gene expression profiling | Q35569555 | ||
In search of targeted therapies for childhood cancer | Q35971733 | ||
Peptide, peptidomimetic and small-molecule drug discovery targeting HIV-1 host-cell attachment and entry through gp120, gp41, CCR5 and CXCR4. | Q36402572 | ||
The AF4-mimetic peptide, PFWT, induces necrotic cell death in MV4-11 leukemia cells | Q36502377 | ||
Xenograft models for the preclinical evaluation of new therapies in acute leukemia | Q36799846 | ||
HOXA9 is required for survival in human MLL-rearranged acute leukemias | Q37129652 | ||
Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents | Q37260555 | ||
The molecular biology of mixed lineage leukemia | Q37522825 | ||
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia | Q38294261 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 253-268 | |
P577 | publication date | 2013-05-01 | |
P1433 | published in | Assay and Drug Development Technologies | Q15767279 |
P1476 | title | Development of a high-throughput screening-compatible assay for the discovery of inhibitors of the AF4-AF9 interaction using AlphaScreen technology | |
P478 | volume | 11 |
Q35571730 | Binding cavities and druggability of intrinsically disordered proteins |
Q38728681 | Current Experimental Methods for Characterizing Protein-Protein Interactions |
Q64087496 | Modulation of Disordered Proteins with a Focus on Neurodegenerative Diseases and Other Pathologies |
Q91789005 | Peptidomimetics for Targeting Protein-Protein Interactions between DOT1L and MLL Oncofusion Proteins AF9 and ENL |
Q35824701 | Protein-protein interactions as drug targets |
Q36989223 | Targeted drug discovery for pediatric leukemia |
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