Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity

scientific article

Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/JM0709034
P698PubMed publication ID18095642

P50authorPeter I DosaQ49769118
P2093author name stringMichael Martin
Michael Morgan
Albert Ren
Andrew J Grottick
Dipanjan Sengupta
Jeffrey M Smith
Stephen Espitia
Robert R Webb
Brian M Smith
James H Tsai
Charlemagne S Gallardo
Charles A Gilson
Christina Bjenning
Douglas M Park
Emily B Prieto
Frederique Menzaghi
Hazel R Saldana
Jeffrey A Schultz
Jon A Covel
Kevin T Whelan
Nigel R A Beeley
Rita R Chen
Scott A Estrada
William J Thomsen
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectlorcaserin hydrochloride hemihydrateQ27135478
obesityQ12174
serotoninQ167934
P304page(s)305-313
P577publication date2007-12-21
P1433published inJournal of Medicinal ChemistryQ900316
P1476titleDiscovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity
P478volume51

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