review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1008605010 |
P356 | DOI | 10.1385/MN:25:3:287 |
P8608 | Fatcat ID | release_tjm2qajfbbffjbnvcuk2xsiabe |
P698 | PubMed publication ID | 12109876 |
P2093 | author name string | David R Brown | |
P2860 | cites work | Prions | Q24633319 |
NMR solution structure of the human prion protein | Q27620845 | ||
Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases | Q27626645 | ||
Crystal structure of the human prion protein reveals a mechanism for oligomerization | Q27634441 | ||
NMR structure of the mouse prion protein domain PrP(121-231) | Q27733163 | ||
Antioxidant activity related to copper binding of native prion protein | Q28141942 | ||
Prion diseases of humans and animals: their causes and molecular basis | Q28209943 | ||
Mice devoid of PrP are resistant to scrapie | Q28249108 | ||
Electron paramagnetic resonance evidence for binding of Cu(2+) to the C-terminal domain of the murine prion protein | Q28367705 | ||
Copper stimulates endocytosis of the prion protein | Q28589040 | ||
Novel proteinaceous infectious particles cause scrapie | Q29547678 | ||
Prion and prejudice: normal protein and the synapse | Q31874508 | ||
Cellular biology of prion diseases | Q33558398 | ||
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. | Q33575860 | ||
Transmissible and genetic prion diseases share a common pathway of neurodegeneration | Q33885223 | ||
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding | Q34084209 | ||
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein | Q34294957 | ||
Role of microglia in neuronal cell death in prion disease | Q47820922 | ||
Effects of oxidative stress on prion protein expression in PC12 cells | Q47924893 | ||
Prion protein is necessary for normal synaptic function | Q48087355 | ||
Prion protein peptide neurotoxicity can be mediated by astrocytes | Q48127864 | ||
Prion proteins carrying pathogenic mutations are resistant to phospholipase cleavage of their glycolipid anchors | Q48171096 | ||
Influence of mutations associated with familial prion-related encephalopathies on biological activity of prion protein peptides | Q48231811 | ||
Astrocytic glutamate uptake and prion protein expression | Q48290049 | ||
Neurotoxicity of a prion protein fragment | Q48304223 | ||
Cellular prion protein localization in rodent and primate brain | Q48388928 | ||
Prion protein fragment interacts with PrP-deficient cells | Q48467628 | ||
Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations | Q48696484 | ||
Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein | Q48769963 | ||
Familial mutations and the thermodynamic stability of the recombinant human prion protein | Q48784818 | ||
Truncated forms of the human prion protein in normal brain and in prion diseases | Q48807964 | ||
Identification of a protein that purifies with the scrapie prion | Q48858653 | ||
Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons. | Q48920441 | ||
Role of microglia and host prion protein in neurotoxicity of a prion protein fragment | Q49050987 | ||
Normal host prion protein necessary for scrapie-induced neurotoxicity | Q49160879 | ||
Familial prion disease mutation alters the secondary structure of recombinant mouse prion protein: implications for the mechanism of prion formation. | Q51986669 | ||
Prion peptide fragment PrP[106-126] forms distinct cation channel types. | Q53904400 | ||
The role of prion peptide structure and aggregation in toxicity and membrane binding. | Q54029824 | ||
Transmission of Two Subacute Spongiform Encephalopathies of Man (Kuru and Creutzfeldt–Jakob Disease) to New World Monkeys | Q54526215 | ||
The cellular prion protein binds copper in vivo | Q56058857 | ||
The Metabolism and Imaging in Live Cells of the Bovine Prion Protein in Its Native Form or Carrying Single Amino Acid Substitutions | Q57356141 | ||
Altered circadian activity rhythms and sleep in mice devoid of prion protein | Q59071240 | ||
Proteasomal Degradation and N-terminal Protease Resistance of the Codon 145 Mutant Prion Protein | Q59505870 | ||
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment | Q72568587 | ||
In vivo cytotoxicity of the prion protein fragment 106-126 | Q73010762 | ||
Cellular uptake of the prion protein fragment PrP106-126 in vitro | Q73254939 | ||
PrP and β‐Amyloid Fragments Activate Different Neurotoxic Mechanisms in Cultured Mouse Cells | Q73494469 | ||
The stimulation of inducible nitric-oxide synthase by the prion protein fragment 106--126 in human microglia is tumor necrosis factor-alpha-dependent and involves p38 mitogen-activated protein kinase | Q73794043 | ||
Effect of flupirtine on Bcl-2 and glutathione level in neuronal cells treated in vitro with the prion protein fragment (PrP106-126) | Q73820551 | ||
Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions | Q74027634 | ||
Folding dynamics and energetics of recombinant prion proteins | Q34305029 | ||
The cellular prion protein binds copper in vivo | Q34450742 | ||
A transmembrane form of the prion protein in neurodegenerative disease | Q34454961 | ||
Normal prion protein has an activity like that of superoxide dismutase. | Q34505606 | ||
Two-octapeptide repeat deletion of prion protein associated with rapidly progressive dementia | Q34516529 | ||
Prion infection impairs the cellular response to oxidative stress | Q35581657 | ||
Separation and properties of cellular and scrapie prion proteins | Q35598678 | ||
Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58 | Q35921884 | ||
Different patterns of truncated prion protein fragments correlate with distinct phenotypes in P102L Gerstmann-Sträussler-Scheinker disease | Q36174780 | ||
Neurofibrillary tangles in Gerstmann-Sträussler-Scheinker syndrome with the A117V prion gene mutation | Q36317012 | ||
Prion protein NMR structure and familial human spongiform encephalopathies | Q36317308 | ||
Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells | Q36802057 | ||
Location and properties of metal-binding sites on the human prion protein. | Q37104327 | ||
Genetic influence on the structural variations of the abnormal prion protein | Q37422460 | ||
Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform. | Q37593764 | ||
A Mutant Prion Protein Displays an Aberrant Membrane Association When Expressed in Cultured Cells | Q38290309 | ||
A monomer-dimer equilibrium of a cellular prion protein (PrPC) not observed with recombinant PrP. | Q38308795 | ||
Insoluble wild-type and protease-resistant mutant prion protein in brains of patients with inherited prion disease | Q39014762 | ||
Familial Creutzfeldt-Jakob disease. Codon 200 prion disease in Libyan Jews | Q39241829 | ||
Prion protein with an E200K mutation displays properties similar to those of the cellular isoform PrP(C). | Q39409269 | ||
Inherited prion diseases and transmission to rodents | Q40537021 | ||
Internalization of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells | Q40775514 | ||
Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells | Q40782705 | ||
Mutant prion proteins are partially retained in the endoplasmic reticulum | Q40783039 | ||
Most pathogenic mutations do not alter the membrane topology of the prion protein | Q40846248 | ||
Prion protein amyloidosis | Q41061823 | ||
A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice | Q41717349 | ||
Altered toxicity of the prion protein peptide PrP106-126 carrying the Ala(117)-->Val mutation | Q41860073 | ||
A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy | Q42688788 | ||
Prion proteins with different conformations accumulate in Gerstmann-Sträussler-Scheinker disease caused by A117V and F198S mutations | Q42746740 | ||
PrPSc-like prion protein peptide inhibits the function of cellular prion protein | Q42998109 | ||
Experimental transmission of Creutzfeldt-Jakob disease and related diseases to rodents | Q43213273 | ||
A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Sträussler-Scheinker disease A117V. | Q43510340 | ||
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Q43522858 | ||
Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region | Q43645286 | ||
Aberrant metal binding by prion protein in human prion disease. | Q43752347 | ||
Glycosylinositol phospholipid anchors of the scrapie and cellular prion proteins contain sialic acid | Q45935884 | ||
A cytoskeletal mechanism for Ca2+ channel metabolic dependence and inactivation by intracellular Ca2+. | Q46030546 | ||
Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor | Q46096263 | ||
Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C. | Q46123074 | ||
Spontaneous neurodegeneration in transgenic mice with mutant prion protein | Q46249938 | ||
Prion protein selectively binds copper(II) ions | Q46492410 | ||
Scrapie prion protein contains a phosphatidylinositol glycolipid | Q46814773 | ||
P433 | issue | 3 | |
P921 | main subject | prion protein family | Q24724413 |
P304 | page(s) | 287-302 | |
P577 | publication date | 2002-06-01 | |
P1433 | published in | Molecular Neurobiology | Q15716645 |
P1476 | title | Molecular advances in understanding inherited prion diseases | |
P478 | volume | 25 |
Q48557029 | Ancestral origins of the prion protein gene D178N mutation in the Basque Country |
Q40645634 | Efficient and specific down-regulation of prion protein expression by RNAi |
Q47695033 | Unexpected high testis-specific transcriptional activity of the cyclin T1 promoter in transgenic mice |