Molecular determinants of glucocorticoid receptor mobility in living cells: the importance of ligand affinity

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Molecular determinants of glucocorticoid receptor mobility in living cells: the importance of ligand affinity is …
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scholarly articleQ13442814

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P356DOI10.1128/MCB.23.6.1922-1934.2003
P932PMC publication ID149474
P698PubMed publication ID12612067
P5875ResearchGate publication ID8105624

P50authorJohn A CidlowskiQ62823441
P2093author name stringMarcel J M Schaaf
P2860cites workThe human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative functionQ24336931
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Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptorsQ28378082
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The DNA-binding and tau2 transactivation domains of the rat glucocorticoid receptor constitute a nuclear matrix-targeting signalQ77221140
Hormone-dependent translocation of vitamin D receptors is linked to transactivationQ77927040
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Characterization of glucocorticoid receptor in HeLa-S3 cellsQ93669787
High mobility of proteins in the mammalian cell nucleusQ29616460
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa BQ29618194
Action of DNA repair endonuclease ERCC1/XPF in living cellsQ33861651
The glucocorticoid receptor: rapid exchange with regulatory sites in living cellsQ33890434
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.Q33929803
Experimental observations of a nuclear matrixQ33932806
The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liverQ33967931
Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cellsQ33968615
Novel glucocorticoid receptor coactivator effector mechanismsQ34221267
Proteasomal inhibition enhances glucocorticoid receptor transactivation and alters its subnuclear trafficking.Q34281710
Purification of two isoforms of hnRNP-U and characterization of their nucleic acid binding activityQ34332571
Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands.Q34347790
Subcellular localization of mineralocorticoid receptors in living cells: effects of receptor agonists and antagonistsQ35975335
ATP-dependent release of glucocorticoid receptors from the nuclear matrixQ36558943
Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcriptionQ36797058
Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimeraQ36800432
Molecular mechanisms of glucocorticoid inhibition of human proopiomelanocortin gene transcriptionQ37544502
Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormoneQ38339139
Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptorsQ40021606
Effects of the heterogeneous nuclear ribonucleoprotein U (hnRNP U/SAF-A) on glucocorticoid-dependent transcription in vivoQ40782896
Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cellsQ40862902
Interaction of steroid hormone receptors with the transcription initiation complexQ41273252
Immunocytochemical analysis of hormone mediated nuclear translocation of wild type and mutant glucocorticoid receptors.Q41279123
Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus.Q41300114
RU486 (mifepristone): mechanisms of action and clinical usesQ41360492
Domains of the human androgen receptor and glucocorticoid receptor involved in binding to the nuclear matrixQ41364826
8-Br-cAMP does not convert antagonists of the glucocorticoid receptor into agonists.Q41394723
Intragenic sequences of the human glucocorticoid receptor complementary DNA mediate hormone-inducible receptor messenger RNA down-regulation through multiple mechanismsQ41423503
Glucocorticoid receptors in ATP-depleted cells. Dephosphorylation, loss of hormone binding, HSP90 dissociation, and ATP-dependent cycling.Q41481578
Novel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple receptor forms in vitro and distinct localization of cytoplasmic and nuclear receptorsQ41720758
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptorQ41721253
Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.Q41721256
Plasma concentrations and receptor binding of RU 486 and its metabolites in humansQ42217667
Species-related differences in steroid-binding specificity of glucocorticoid receptors in lungQ42274300
Vitamin B6 influences glucocorticoid receptor-dependent gene expression.Q42485328
FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependentQ43516734
Nuclear cytoplasmic shuttling by thyroid hormone receptors. multiple protein interactions are required for nuclear retentionQ43517885
The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence proteinQ43615480
The presence of both the amino- and carboxyl-terminal domains in the AR is essential for the completion of a transcriptionally active form with coactivators and intranuclear compartmentalization common to the steroid hormone receptors: a three-dimenQ43940241
Multiple and cooperative trans-activation domains of the human glucocorticoid receptorQ46099369
Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptorQ56911499
Type II antagonists impair the DNA binding of steroid hormone receptors without affecting dimerizationQ61818659
Steroid hormone receptor localization in the nuclear matrix: interaction with acceptor sitesQ69478969
hnRNP proteins and B23 are the major proteins of the internal nuclear matrix of HeLa S3 cellsQ71622196
Multiple forms of nuclear binding of glucocorticoid-receptor complexes in rat thymocytesQ72076221
Nuclear distribution of transcription factors in relation to sites of transcription and RNA polymerase IIQ73606331
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1922-1934
P577publication date2003-03-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleMolecular determinants of glucocorticoid receptor mobility in living cells: the importance of ligand affinity
P478volume23

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