Expression of human beta-defensins in conjunctival epithelium: relevance to dry eye disease

scientific article

Expression of human beta-defensins in conjunctival epithelium: relevance to dry eye disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1167/IOVS.02-1301
P932PMC publication ID1497873
P698PubMed publication ID12939294

P2093author name stringWilliam L Miller
Alison M McDermott
Srihari Narayanan
P2860cites workOcular surface epithelia express mRNA for human beta defensin-2.Q41700287
Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.Q41705704
Antimicrobial peptides of vertebratesQ41729805
Staining of the conjunctiva and conjunctival tear filmQ41861614
Antimicrobial defensin peptides of the human ocular surfaceQ42230623
Secretion of proinflammatory cytokines by human conjunctival epithelial cellsQ42441794
Bacteriology and tear protein profiles of the dry eyeQ42614549
Identification of beta-defensins in human conjunctivaQ42743976
Investigation of beta defensin gene expression in the ocular anterior segment by semiquantitative RT-PCR.Q42856164
Human beta-defensin 2 is up-regulated during re-epithelialization of the corneaQ43637116
Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye diseaseQ43723395
Comparison of fluorescein break-up time measurement reproducibility using standard fluorescein strips versus the Dry Eye Test (DET) method.Q43783618
Conjunctival T-cell subpopulations in Sjögren's and non-Sjögren's patients with dry eye.Q45950875
Neutrophil defensins induce histamine secretion from mast cells: mechanisms of actionQ46305548
Lissamine green. Vital staining of cornea and conjunctiva.Q50966765
Impression cytologyQ68129996
Keratoconjunctivitis sicca and corneal ulcersQ68759473
A new method for measuring tearsQ70447932
Defensins are mitogenic for epithelial cells and fibroblastsQ70681773
Model for ocular tear film functionQ71792663
Ocular surface damage and tear lactoferrin in dry eye syndromeQ72418727
Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis siccaQ72993423
Neutrophil alpha-defensin human neutrophil peptide modulates cytokine production in human monocytes and adhesion molecule expression in endothelial cellsQ74027433
Expression of human beta-defensins in intraocular tissuesQ74248030
beta-Defensins: endogenous antibiotics of the innate host defense responseQ77319976
Does androgen insufficiency cause lacrimal gland inflammation and aqueous tear deficiency?Q77425439
The pathology of dry eye: the interaction between the ocular surface and lacrimal glandsQ77575256
Relationship of impression cytology and tear ferning to reports of dry eyeQ78159226
Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6Q22010648
Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibioticQ24290539
Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glandsQ24548834
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensinsQ27639439
Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattractionQ28204611
Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activityQ28210164
Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and miceQ28218903
A peptide antibiotic from human skinQ28242199
Structure, function, and membrane integration of defensinsQ28270856
Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophilsQ28277848
hBD-1: a novel beta-defensin from human plasmaQ28294850
DefensinsQ28297042
Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathwayQ28612022
Relationship between goblet cell density and tear function tests.Q31126267
Effect of oral contraceptives on tear physiologyQ32060821
Fas- and interferon gamma-induced apoptosis in Chang conjunctival cells: further investigations.Q33180870
Assessment of the European classification criteria for Sjögren's syndrome in a series of clinically defined cases: results of a prospective multicentre study. The European Study Group on Diagnostic Criteria for Sjögren's SyndromeQ33578726
Regulation of human beta-defensins by gastric epithelial cells in response to infection with Helicobacter pylori or stimulation with interleukin-1.Q33600460
Androgens and dry eye in Sjögren's syndromeQ33692681
Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrierQ33898454
Current status of defensins and their role in innate and adaptive immunityQ34108985
Defensin Expression by the Cornea: Multiple Signalling Pathways Mediate IL-1β Stimulation of hBD-2 Expression by Human Corneal Epithelial CellsQ34758069
Production of beta-defensins by human airway epitheliaQ36758628
Is the dry eye contact lens wearer at risk? Yes.Q37928284
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.Q40692879
CCLRU standards for success of daily and extended wear contact lenses.Q40902371
Interferon-gamma induces apoptosis and expression of inflammation-related proteins in Chang conjunctival cells.Q40930968
Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes.Q40948258
Effect of defensins on interleukin-8 synthesis in airway epithelial cellsQ41112818
Differential diagnosis of dry eye conditionsQ41231731
P433issue9
P407language of work or nameEnglishQ1860
P921main subjecteye diseaseQ3041498
P304page(s)3795-3801
P577publication date2003-09-01
P1433published inInvestigative Ophthalmology Visual ScienceQ6060707
P1476titleExpression of human beta-defensins in conjunctival epithelium: relevance to dry eye disease
P478volume44

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cites work (P2860)
Q41687406A hybrid cationic peptide composed of human β-defensin-1 and humanized θ-defensin sequences exhibits salt-resistant antimicrobial activity
Q34758093A review of antimicrobial peptides and their therapeutic potential as anti-infective drugs
Q34507671Antimicrobial peptides and wound healing: biological and therapeutic considerations
Q37954721Antimicrobial peptides: key components of the innate immune system
Q50517284Calcium regulation by thermo- and osmosensing transient receptor potential vanilloid channels (TRPVs) in human conjunctival epithelial cells.
Q34522531Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis
Q39799778Cis-urocanic acid suppresses UV-B-induced interleukin-6 and -8 secretion and cytotoxicity in human corneal and conjunctival epithelial cells in vitro.
Q34347323Comparison of the effects of different lens-cleaning solutions on the protein profiles of human conjunctival cells
Q35904679Conjunctival impression cytology versus routine tear function tests for dry eye evaluation in contact lens wearers
Q35594084Defensins and other antimicrobial peptides at the ocular surface
Q36799601Dry eye disease and microbial keratitis: is there a connection?
Q39242998Effect of hyperosmolality on beta-defensin gene expression by human corneal epithelial cells
Q47986044Expression of Antimicrobial Peptides by Uveal and Cutaneous Melanoma Cells and Investigation of Their Role in Tumor Cell Migration and Vasculogenic Mimicry
Q33232896Expression of beta defensins in ocular surface tissue of experimentally developed allergic conjunctivitis mouse model
Q34758057Human cathelicidin (LL-37), a multifunctional peptide, is expressed by ocular surface epithelia and has potent antibacterial and antiviral activity
Q33835386Immunobiology of herpes simplex virus and cytomegalovirus infections of the fetus and newborn
Q36318070Impression cytology of the ocular surface
Q37453774Impression cytology: recent advances and applications in dry eye disease.
Q41852819In vitro activity of human beta-defensin 2 against Pseudomonas aeruginosa in the presence of tear fluid
Q35030919In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).
Q42572882Molecular mechanism of ocular surface damage: application to an in vitro dry eye model on human corneal epithelium
Q36726165Ocular surface expression and in vitro activity of antimicrobial peptides
Q91937066Presence of Histatin-1 in Human Tears and Association with Aqueous Deficient Dry Eye Diagnosis: A Preliminary Study
Q42446142Pseudomonas aeruginosa induces interleukin-8 (IL-8) gene expression in human conjunctiva through the recruitment of both RelA and CCAAT/enhancer-binding protein beta to the IL-8 promoter
Q36799596Role of host-defence peptides in eye diseases
Q30318679Roles of human beta-defensins in innate immune defense at the ocular surface: arming and alarming corneal and conjunctival epithelial cells
Q50041932Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice.
Q89349313Suppression of Th1-Mediated Keratoconjunctivitis Sicca by Lifitegrast
Q34770248Surfactant protein D contributes to ocular defense against Pseudomonas aeruginosa in a murine model of dry eye disease.
Q35593328TLRs and NODs mRNA expression pattern in healthy mouse eye.
Q54410145The corneal expression of antimicrobial peptides during experimental fungal keratitis.
Q37017370The role of antimicrobial peptides at the ocular surface
Q34629176Toll-like receptor activation modulates antimicrobial peptide expression by ocular surface cells
Q36159551Toll-like receptor expression and activation in mice with experimental dry eye.
Q82973353Toll-like receptors and the eye
Q55182342Triggering Receptors Expressed on Myeloid Cells 2 Promotes Corneal Resistance Against Pseudomonas aeruginosa by Inhibiting Caspase-1-Dependent Pyroptosis.

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