Lysostaphin-coated titan-implants preventing localized osteitis by Staphylococcus aureus in a mouse model

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Lysostaphin-coated titan-implants preventing localized osteitis by Staphylococcus aureus in a mouse model is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9k5940W
P356DOI10.1371/JOURNAL.PONE.0115940
P8608Fatcat IDrelease_upcw23crhrh3fpdzouolpbifym
P932PMC publication ID4275259
P698PubMed publication ID25536060
P5875ResearchGate publication ID270001252

P50authorSascha FlohéQ46920067
P2093author name stringMartin Scholz
Joachim Windolf
Ceylan D Windolf
Tim Lögters
P2860cites workA new intra-arterial delivery platform for pro-arteriogenic compounds to stimulate collateral artery growth via transforming growth factor-beta1 release.Q50949576
Biomechanical and allergological characteristics of a biodegradable poly(D,L-lactic acid) coating for orthopaedic implants.Q51400098
Changing the release kinetics of gentamicin from poly(D,L-lactide) implant coatings using only one polymer.Q52896788
Surface-associated protein from Staphylococcus aureus stimulates osteoclastogenesis: possible role in S. aureus-induced bone pathology.Q54115720
Gentamycin delivered from a PDLLA coating of metallic implantsQ56992720
Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse modelQ81234087
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Lysostaphin Disrupts Staphylococcus aureus and Staphylococcus epidermidis Biofilms on Artificial SurfacesQ24650674
Lysostaphin cream eradicates Staphylococcus aureus nasal colonization in a cotton rat modelQ24682172
Crystal structure of the antimicrobial peptidase lysostaphin fromStaphylococcus simulansQ27684730
Bacterial biofilms: a common cause of persistent infectionsQ27861033
Lysostaphin treatment of methicillin-resistant Staphylococcus aureus keratitis in the rabbitQ28143682
LYSOSTAPHIN: A NEW BACTERIOLYTIC AGENT FOR THE STAPHYLOCOCCUSQ28156580
Antibiotic resistance of bacteria in biofilmsQ28207706
Lysostaphin treatment of experimental methicillin-resistant Staphylococcus aureus aortic valve endocarditisQ28379547
The future of biologic coatings for orthopaedic implantsQ28394906
Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical dataQ30597709
Biodegradable poly(D,L-lactide) coating of implants for continuous release of growth factorsQ31926776
Lysostaphin as a potential therapeutic agent for staphylococcal biofilm eradicationQ33232677
Staphylococcus aureus adhesion to bone matrix and bone-associated biomaterialsQ33607466
Quorum sensing in Staphylococcus infectionsQ33630510
Lysostaphin: A Staphylococcal Bacteriolysin with Potential Clinical ApplicationsQ33664443
Staphylococcus and biofilmsQ34600780
The relative contributions of physical structure and cell density to the antibiotic susceptibility of bacteria in biofilmsQ36018792
Biofilm in implant infections: its production and regulation.Q36341333
The significance of infection related to orthopedic devices and issues of antibiotic resistanceQ36346573
ica and beyond: biofilm mechanisms and regulation in Staphylococcus epidermidis and Staphylococcus aureusQ36785892
Lysostaphin: an antistaphylococcal agentQ37209589
Antibiotic resistance of bacterial biofilmsQ37690946
Emerging pathogenetic mechanisms of the implant-related osteomyelitis by Staphylococcus aureusQ37957607
Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materialsQ38018423
A review of the biomaterials technologies for infection-resistant surfacesQ38129576
Recent lessons for the management of bone and joint infectionsQ38152064
The immunomodulatory activity of Staphylococcus aureus products derived from biofilm and planktonic cultures.Q42131269
Inhibition of the Activity of Both Domains of Lysostaphin through Peptidoglycan Modification by the Lysostaphin Immunity ProteinQ42411103
Bap, a Staphylococcus aureus surface protein involved in biofilm formationQ42737702
Efficacy of a norvancomycin-loaded, PDLLA-coated plate in preventing early infection of rabbit tibia fractureQ43052929
Microbiology of the infected knee arthroplasty: report from the Swedish Knee Arthroplasty Register on 426 surgically revised casesQ43239635
Molecular Properties of Lysostaphin, a Bacteriolytic Agent Specific for Staphylococcus aureusQ43462980
Local application of zoledronic acid incorporated in a poly(D,L-lactide)-coated implant accelerates fracture healing in ratsQ43677840
Lysostaphin is effective in treating methicillin-resistant Staphylococcus aureus endophthalmitis in the rabbitQ43755005
Studies with lysotaphin. II. Lysostaphin sensitivity of 230 strains of Staph. aureus of animal originQ44228104
Immunity to lysostaphin and its therapeutic value for ocular MRSA infections in the rabbit.Q44231124
Implant-associated posttraumatic osteomyelitis: collateral damage by local host defense?Q44997805
Lysostaphin eradicates established Staphylococcus aureus biofilms in jugular vein catheterized mice.Q46034505
Post-traumatic osteomyelitis: analysis of inflammatory cells recruited into the site of infectionQ47377003
Implant-associated localized osteitis in murine femur fracture by biofilm forming Staphylococcus aureus: a novel experimental modelQ47955099
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectStaphylococcus aureusQ188121
P304page(s)e115940
P577publication date2014-12-23
P1433published inPLOS OneQ564954
P1476titleLysostaphin-coated titan-implants preventing localized osteitis by Staphylococcus aureus in a mouse model
P478volume9

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cites work (P2860)
Q61658129A New Bioactive Compound From the Marine Sponge-Derived sp. SBT348 Inhibits Staphylococcal Growth and Biofilm Formation
Q35846513A new animal model for delayed osseous union secondary to osteitis
Q95643042A systematic review on current osteosynthesis-associated infection animal fracture models
Q40796792An in vitro study on disinfection of titanium surfaces
Q58768791Coatings as the useful drug delivery system for the prevention of implant-related infections
Q64095049Effect of antibiotic infused calcium sulfate/hydroxyapatite (CAS/HA) insets on implant-associated osteitis in a femur fracture model in mice
Q48149676Effect of hyperbaric oxygen therapy (HBO) on implant-associated osteitis in a femur fracture model in mice.
Q54212204Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing.
Q92070305Impact of Bacterial Infections on Osteogenesis: Evidence From In Vivo Studies
Q90473947Nonconventional Therapeutics against Staphylococcus aureus
Q38844138Osteogenic differentiation and proliferation of bone marrow-derived mesenchymal stromal cells on PDLLA + BMP-2-coated titanium alloy surfaces
Q37482155Prevention and treatment of Staphylococcus aureus biofilms
Q26766421Staphylococcal Superantigens Spark Host-Mediated Danger Signals
Q40427118Thermally triggered release of the bacteriophage endolysin CHAPK and the bacteriocin lysostaphin for the control of methicillin resistant Staphylococcus aureus (MRSA)

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