Resistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent of anti-viral type-I interferon.

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Resistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent of anti-viral type-I interferon. is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...865801Z
P356DOI10.1371/JOURNAL.PONE.0065801
P932PMC publication ID3675064
P698PubMed publication ID23762429
P5875ResearchGate publication ID237200696

P50authorV. Wee YongQ56101901
Grant McFaddenQ88652661
P2093author name stringPeter A Forsyth
Franz J Zemp
Brienne A McKenzie
Lori Maxwell
Xueqing Lun
Karlyne M Reilly
P2860cites workInnate cellular response to virus particle entry requires IRF3 but not virus replicationQ24607212
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1Q24651548
Comprehensive genomic characterization defines human glioblastoma genes and core pathwaysQ24656128
Oncolytic virus therapy for glioblastoma multiforme: concepts and candidatesQ27007519
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effectsQ28511432
Malignant gliomas in adultsQ29615708
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell linesQ29615823
Defective translational control facilitates vesicular stomatitis virus oncolysisQ42831942
Human and mouse IFN-beta gene therapy exhibits different anti-tumor mechanisms in mouse modelsQ44669457
Intraventricular injection of myxoma virus results in transient expression of viral protein in mouse brain ependymal and subventricular cells.Q45372866
Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrierQ45560504
Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogensQ48559424
Prognosis of gliomas in the 1970s and todayQ48921212
Benefits of interferon-β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study.Q55463256
Collagens, integrins and the mesenchymal drift in glioblastomas: A comparison of biopsy specimens, spheroid and early monolayer culturesQ55481758
Induction of experimental allergic encephalomyelitis in genetically resistant strains of miceQ59084927
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretionQ29617359
Behavior of a cloned murine interferon alpha/beta receptor expressed in homospecific or heterospecific background.Q30839933
Role for gamma interferon in control of herpes simplex virus type 1 reactivation.Q33645342
Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN productionQ33667768
Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBMQ33712977
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virusQ33908950
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.Q34032640
The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle studyQ34124333
Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomasQ34297434
Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma.Q34343768
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and humanQ34503355
Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapiesQ35021348
Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomasQ35216380
Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin.Q35234447
Oncolytic virotherapy for pancreatic cancerQ35590996
Genetic pathways to primary and secondary glioblastomaQ35757144
Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma modelQ35800497
Myxoma virus sensitizes cancer cells to gemcitabine and is an effective oncolytic virotherapeutic in models of disseminated pancreatic cancerQ35876172
The effect of mouse strain on herpes simplex virus type 1 (HSV-1) infection of the central nervous system (CNS)Q35968286
Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the peripheryQ36155597
Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastasesQ36167296
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.Q36457107
Type I interferon response in the central nervous systemQ36780318
Treating brain tumor-initiating cells using a combination of myxoma virus and rapamycinQ36943893
Neuroimmunology of central nervous system viral infections: the cells, molecules and mechanisms involved.Q37037317
Patterns of antigenic expression of human glioma cellsQ37430142
Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomasQ37452837
Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effectsQ37512434
Cloning and expression of murine immune interferon cDNAQ37514363
Oncolytic viruses as experimental treatments for malignant gliomas: using a scourge to treat a devilQ37756317
Membrane perturbation elicits an IRF3-dependent, interferon-independent antiviral responseQ38631749
Myxoma virus: propagation, purification, quantification, and storageQ39707862
Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycinQ39752828
Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signalingQ39849004
Therapeutic implications of interferon regulatory factor (IRF)-1 and IRF-2 in diffusely infiltrating astrocytomas (DIA): response to interferon (IFN)-beta in glioblastoma cells and prognostic value for DIA.Q40368455
Therapy of a murine model of pediatric brain tumors using a herpes simplex virus type-1 ICP34.5 mutant and demonstration of viral replication within the CNS.Q41148859
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectoncolytic virusQ1560099
Myxoma virusQ6949366
P304page(s)e65801
P577publication date2013-06-06
P1433published inPLOS OneQ564954
P1476titleResistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent of anti-viral type-I interferon
P478volume8

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cites work (P2860)
Q37269034ABCG1 maintains high-grade glioma survival in vitro and in vivo.
Q30395978Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus.
Q35545752In vitro screen of a small molecule inhibitor drug library identifies multiple compounds that synergize with oncolytic myxoma virus against human brain tumor-initiating cells
Q38746434N-Myc expression enhances the oncolytic effects of vesicular stomatitis virus in human neuroblastoma cells
Q92618072Neurofibromin 1 expression is negatively correlated with malignancy and prognosis of epithelial ovarian cancer
Q92633759Oncolytic Virotherapy with Myxoma Virus
Q34405325Oncolytic immunotherapy: where are we clinically?
Q37672257Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
Q39045958The role of the immune system in neurofibromatosis type 1-associated nervous system tumors
Q51846287Tumor Restrictions to Oncolytic Virus.
Q35657822Unlocking the promise of oncolytic virotherapy in glioma: combination with chemotherapy to enhance efficacy
Q94032022Using the Collaborative Cross to Study the Role of Genetic Diversity in Cancer-Related Phenotypes
Q63246502Virus-Based Immunotherapy of Glioblastoma

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