Staphylococcus aureus biofilms decrease osteoblast viability, inhibits osteogenic differentiation, and increases bone resorption in vitro

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Staphylococcus aureus biofilms decrease osteoblast viability, inhibits osteogenic differentiation, and increases bone resorption in vitro is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1025775533
P356DOI10.1186/1471-2474-14-187
P932PMC publication ID3691632
P698PubMed publication ID23767824
P5875ResearchGate publication ID239525003

P2093author name stringJoseph C Wenke
Carlos J Sanchez
Desiree R Romano
Sharanda K Hardy
Catherine L Ward
Ronald L Woodbury
Brady J Hurtgen
Christopher R Rathbone
Alex V Trevino
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Staphylococcus aureus protein A binding to osteoblast tumour necrosis factor receptor 1 results in activation of nuclear factor kappa B and release of interleukin-6 in bone infectionQ39244124
Mode of growth of bacterial pathogens in chronic polymicrobial human osteomyelitisQ40221904
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Infectious complications and soft tissue injury contribute to late amputation after severe lower extremity traumaQ42610986
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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Bacterial biofilms: from the natural environment to infectious diseasesQ29547677
OsteomyelitisQ33205211
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cellsQ33510340
Biofilm development by clinical isolates of Staphylococcus spp. from retrieved orthopedic prosthesesQ33756629
Staphylococcus aureus protein A binds to osteoblasts and triggers signals that weaken bone in osteomyelitisQ33883360
Staphylococcus aureus Biofilm and Planktonic cultures differentially impact gene expression, mapk phosphorylation, and cytokine production in human keratinocytesQ33938600
Internal control genes for quantitative RT-PCR expression analysis in mouse osteoblasts, osteoclasts and macrophagesQ34047702
Staphylococcus aureus protein A plays a critical role in mediating bone destruction and bone loss in osteomyelitisQ34336558
Biofilm formation by clinical isolates and the implications in chronic infectionsQ34565318
Association between methicillin susceptibility and biofilm regulation in Staphylococcus aureus isolates from device-related infectionsQ35784526
Differential effects of planktonic and biofilm MRSA on human fibroblastsQ35798739
Osteoblast responses to bacterial pathogens: a previously unappreciated role for bone-forming cells in host defense and disease progressionQ35942434
The OPG/RANKL/RANK system in metabolic bone diseases.Q35992034
Biofilm theory can guide the treatment of device-related orthopaedic infections.Q36213794
Functions of RANKL/RANK/OPG in bone modeling and remodelingQ36700779
A strategy for identifying gel-separated proteins in sequence databases by MS alone.Q36827973
The biological role of death and lysis in biofilm developmentQ36908387
Osteomyelitis and the role of biofilms in chronic infectionQ37032879
Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell deathQ37145980
Adherence of coagulase-negative staphylococci to plastic tissue culture plates: a quantitative model for the adherence of staphylococci to medical devicesQ37283349
Host defense and pathogenesis in Staphylococcus aureus infectionsQ37356490
Impact of sarA on daptomycin susceptibility of Staphylococcus aureus biofilms in vivoQ37392784
Chlamydia trachomatis infection inhibits both Bax and Bak activation induced by staurosporineQ37521667
Regulation of bone development and extracellular matrix protein genes by RUNX2.Q37569808
Suicide and fratricide in bacterial biofilmsQ37620259
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P921main subjectStaphylococcus aureusQ188121
biofilmQ467410
osteoblastQ917177
P304page(s)187
P577publication date2013-06-14
P1433published inBMC Musculoskeletal DisordersQ15751716
P1476titleStaphylococcus aureus biofilms decrease osteoblast viability, inhibits osteogenic differentiation, and increases bone resorption in vitro
P478volume14

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