S-Adenosylmethionine revisited: its essential role in the regulation of liver function

scientific article

S-Adenosylmethionine revisited: its essential role in the regulation of liver function is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0741-8329(02)00228-8
P698PubMed publication ID12163144

P2093author name stringIsabel Pérez-Mato
Fernando J Corrales
José M Mato
Elena R García-Trevijano
M Ujue Latasa
L A Martínez-Cruz
Manuel M del Pino
María L Martínez-Chantar
Matiías A Avila
P2860cites workCloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II)Q22011144
S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liverQ28575436
Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liverQ28581508
S-adenosylmethionine synthesis: molecular mechanisms and clinical implicationsQ28646532
Prevention and treatment of liver fibrosis based on pathogenesisQ33661202
Amino acid metabolism in liver diseaseQ33715385
Methionine metabolism in mammalsQ34366989
Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver diseaseQ34544061
Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferationQ35885731
Biochemistry and pharmacology of S-adenosyl-L-methionine and rationale for its use in liver diseaseQ37785034
Labile methyl groups and the promotion of cancerQ38164562
Methionine adenosyltransferase: structure and functionQ40799580
Liver-specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation.Q40907508
Carnitine metabolism in chronic liver diseaseQ41206490
Cytochrome P-4502E1: its physiological and pathological roleQ41441345
Inhibition of liver methionine adenosyltransferase gene expression by 3-methylcolanthrene: protective effect of S-adenosylmethionine.Q43574315
Altered liver gene expression in CCl4-cirrhotic rats is partially normalized by insulin-like growth factor-I.Q43890234
Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrixQ45078167
Nitric oxide inactivates rat hepatic methionine adenosyltransferase In vivo by S-nitrosylationQ45889385
Changes in S-adenosylmethionine synthetase in human liver cancer: molecular characterization and significanceQ46135216
Specific loss of the high-molecular-weight form of S-adenosyl-L-methionine synthetase in human liver cirrhosisQ47176613
Consensus nomenclature for the mammalian methionine adenosyltransferase genes and gene productsQ48777148
Defective methionine metabolism in cirrhosis: relation to severity of liver disease.Q51605191
S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial.Q55033177
The effect of ethanol on one-carbon metabolism: Increased methionine catabolism and lipotrope methyl-group wastageQ57677683
Hepatic Phosphatidylethanolamine Methyltransferase Activity Is Decreased by Ethanol and Increased by PhosphatidylcholineQ61785760
Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinomaQ62727088
Labile methyl balances for normal humans on various dietary regimensQ66925044
S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injuryQ67555817
S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosisQ68257612
Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled studyQ68512879
S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboonQ68716606
Effects of prolonged ethanol feeding on methionine metabolism in rat liverQ69015074
The leaky gut of alcoholism: possible route of entry for toxic compoundsQ72571576
In vivo regulation by glutathione of methionine adenosyltransferase S-nitrosylation in rat liverQ73225054
Polyenylphosphatidylcholine attenuates alcohol-induced fatty liver and hyperlipemia in ratsQ73648925
Interaction of liver methionine adenosyltransferase with hydroxyl radicalQ73804234
Decreased carnitine biosynthesis in rats with secondary biliary cirrhosisQ73825689
Hepatocyte growth factor induces MAT2A expression and histone acetylation in rat hepatocytes: role in liver regenerationQ73853309
Regulation by hypoxia of methionine adenosyltransferase activity and gene expression in rat hepatocytesQ74133491
S-Adenosylmethionine modulates inducible nitric oxide synthase gene expression in rat liver and isolated hepatocytesQ77335023
Role of S-adenosyl-L-methionine in the treatment of liver diseasesQ78001335
Rate of Disappearance From Plasma of Intravenously Administered Methionine in Patients With Liver DamageQ81148006
P433issue3
P304page(s)163-167
P577publication date2002-07-01
P1433published inAlcoholQ15724430
P1476titleS-Adenosylmethionine revisited: its essential role in the regulation of liver function
P478volume27

Reverse relations

cites work (P2860)
Q405711585'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.
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Q36752271Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis
Q36016487Alcohol-induced S-adenosylhomocysteine accumulation in the liver sensitizes to TNF hepatotoxicity: possible involvement of mitochondrial S-adenosylmethionine transport
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Q46937417Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells.
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