Miniature short hairpin RNA screens to characterize antiproliferative drugs

scientific article

Miniature short hairpin RNA screens to characterize antiproliferative drugs is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1534/G3.113.006437
P932PMC publication ID3737177
P698PubMed publication ID23797109
P5875ResearchGate publication ID241697192

P50authorLawrence E HeislerQ50211251
Jason MoffatQ83455827
Iain M WallaceQ37393604
P2093author name stringSaranya Kittanakom
Guri Giaever
Anthony Arnoldo
Anuradha Surendra
Kevin R Brown
Corey Nislow
Dax Torti
Tada Kunavisarut
P2860cites workA screen of shRNAs targeting tumor suppressor genes to identify factors involved in A549 paclitaxel sensitivity.Q40056489
Potential role of short hairpin RNA targeting epidermal growth factor receptor in growth and sensitivity to drugs of human lung adenocarcinoma cellsQ40324022
Synthesis and antitumor activity of sulfur-containing 9-anilinoacridinesQ40440109
Genomic profiling of drug sensitivities via induced haploinsufficiency.Q41614030
Integrating interacting drugs and genetic variations to improve the predictability of warfarin maintenance dose in Chinese patientsQ42722677
Lessons from 60 years of pharmaceutical innovationQ43447062
Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjectsQ43566532
Correlation between Topo II alpha expression and chemosensitivity testing for Topo II-targeting drugs in gynaecological carcinomasQ43632421
Genetic variants in CYP (-1A2, -2C9, -2C19, -3A4 and -3A5), VKORC1 and ABCB1 genes in a black South African population: a window into diversityQ43879115
Relative contribution of VKORC1, CYP2C9, and INR response to warfarin stable dose.Q46038766
Sulforhodamine B colorimetric assay for cytotoxicity screening.Q51032435
The influence of genetic polymorphisms and interacting drugs on initial response to warfarin in Chinese patients with heart valve replacement.Q53159003
Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)Q57412648
Antifertility treating with long term gossypolQ77062601
Aberrant expression of the apoptosis-related proteins BAK and MCL1 in T cells in multiple sclerosisQ83275600
Mcl1 becomes ubiquitin-ous: new opportunities to antagonize a pro-survival proteinQ83968238
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repairQ24337655
Cellular and molecular mechanisms of metformin: an overviewQ27013561
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotesQ28238338
Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophreniaQ28254349
Off-target effects of psychoactive drugs revealed by genome-wide assays in yeastQ28473277
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivityQ29547693
Quantitative phenotyping via deep barcode sequencing.Q30482301
Median absolute deviation to improve hit selection for genome-scale RNAi screensQ33316277
A comparative analysis of DNA barcode microarray feature sizeQ33510271
A comprehensive platform for highly multiplexed mammalian functional genetic screensQ33891511
Targeting the cancer kinome through polypharmacologyQ33893019
Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samplesQ34020284
Trends in the exploitation of novel drug targetsQ34205159
Systems approaches to polypharmacology and drug discoveryQ34746314
Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study of DiabetesQ34862358
Chemogenomic profiling: identifying the functional interactions of small molecules in yeastQ35554300
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemiaQ35564841
Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysisQ35842470
The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control studyQ36001145
Targeting programmed cell death pathways with experimental therapeutics: opportunities in high-risk neuroblastomaQ36146025
BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonistsQ36948615
Kinase requirements in human cells: III. Altered kinase requirements in VHL-/- cancer cells detected in a pilot synthetic lethal screenQ36954859
Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists.Q37163339
Molecular networks in drug discovery.Q37798843
The importance of new companies for drug discovery: origins of a decade of new drugsQ37804687
Metformin and cancer therapy.Q37962127
Mule determines the apoptotic response to HDAC inhibitors by targeted ubiquitination and destruction of HDAC2.Q39455093
Lentiviral shRNA screen of human kinases identifies PLK1 as a potential therapeutic target for osteosarcomaQ39741662
An epidermal growth factor inhibitor, Gefitinib, induces apoptosis through a p53-dependent upregulation of pro-apoptotic molecules and downregulation of anti-apoptotic molecules in human lung adenocarcinoma A549 cellsQ39923279
P4510describes a project that useslimmaQ112236343
P433issue8
P304page(s)1375-1387
P577publication date2013-08-07
P1433published inG3Q5512701
P1476titleMiniature short hairpin RNA screens to characterize antiproliferative drugs
P478volume3