| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1000101669 |
| P356 | DOI | 10.1038/NATURE07018 |
| P932 | PMC publication ID | 2743009 |
| P698 | PubMed publication ID | 18528332 |
| P5875 | ResearchGate publication ID | 5328192 |
| P50 | author | Jack Szostak | Q104600 |
| Sheref S. Mansy | Q47187325 | ||
| P2093 | author name string | Sylvia Tobé | |
| Mathangi Krishnamurthy | |||
| Douglas A Treco | |||
| Jason P Schrum | |||
| P2860 | cites work | Permeation of protons, potassium ions, and small polar molecules through phospholipid bilayers as a function of membrane thickness | Q24531389 |
| Evolution of the first metabolic cycles | Q24559932 | ||
| Experimental models of primitive cellular compartments: encapsulation, growth, and division | Q28212244 | ||
| RNA catalysis in model protocell vesicles | Q28821481 | ||
| Chemical primer extension: efficiently determining single nucleotides in DNA. | Q33223690 | ||
| Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose | Q33936301 | ||
| A kinetic study of the growth of fatty acid vesicles | Q34186785 | ||
| Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles | Q34330728 | ||
| The emergence of competition between model protocells | Q34346506 | ||
| Why nature chose phosphates | Q34658466 | ||
| The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and protons | Q36435478 | ||
| Liposomes from ionic, single-chain amphiphiles | Q36640375 | ||
| Models of primitive cellular life: polymerases and templates in liposomes. | Q36741713 | ||
| Oligomerization of activated D- and L-guanosine mononucleotides on templates containing D- and L-deoxycytidylate residues | Q36791466 | ||
| Lipid synthesis under hydrothermal conditions by Fischer-Tropsch-type reactions | Q38501148 | ||
| Oligomerization of 3'-amino-3'deoxyguanosine-5'phosphorimidazolidate on a d(CpCpCpCpC) template | Q43728531 | ||
| Self-assembled vesicles of monocarboxylic acids and alcohols: conditions for stability and for the encapsulation of biopolymers | Q43875192 | ||
| Mechanism of unassisted ion transport across membrane bilayers | Q46146180 | ||
| Membrane water and solute permeability determined quantitatively by self-quenching of an entrapped fluorophore | Q46169031 | ||
| Effects of farnesol on the physical properties of DMPC membranes | Q46553743 | ||
| Synthesis of long prebiotic oligomers on mineral surfaces | Q47833460 | ||
| The search for the chemistry of life's origin | Q56490408 | ||
| Boundary structures are formed by organic components of the Murchison carbonaceous chondrite | Q56874098 | ||
| Production of RNA by a polymerase protein encapsulated within phospholipid vesicles | Q58001497 | ||
| Matrix Effect in the Size Distribution of Fatty Acid Vesicles | Q64028861 | ||
| P433 | issue | 7200 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 122-125 | |
| P577 | publication date | 2008-06-04 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Template-directed synthesis of a genetic polymer in a model protocell | |
| P478 | volume | 454 |
| Q21145705 | A bioenergetic basis for membrane divergence in archaea and bacteria |
| Q44251102 | A remarkable self-organization process as the origin of primitive functional cells. |
| Q57499611 | A stochastic model of catalytic reaction networks in protocells |
| Q38328110 | Activated ribonucleotides undergo a sugar pucker switch upon binding to a single-stranded RNA template |
| Q78287375 | Adaptive Polymersome Nanoreactors |
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| Q50951066 | Amphiphilic Nanoparticles Control the Growth and Stability of Lipid Bilayers with Open Edges. |
| Q35623343 | An embryo of protocells: The capsule of graphene with selective ion channels |
| Q35173025 | An optimal degree of physical and chemical heterogeneity for the origin of life? |
| Q28651014 | An origin-of-life reactor to simulate alkaline hydrothermal vents |
| Q40838602 | Ancient Systems of Sodium/Potassium Homeostasis as Predecessors of Membrane Bioenergetics |
| Q37977720 | Approaches to chemical synthetic biology. |
| Q36474553 | Aqueous phase separation as a possible route to compartmentalization of biological molecules |
| Q37574221 | Artificial cells: from basic science to applications |
| Q35925587 | Bioactive cell-like hybrids coassembled from (glyco)dendrimersomes with bacterial membranes |
| Q64271761 | Building blocks for recognition-encoded oligoesters that form H-bonded duplexes |
| Q47810948 | Catanionic Coacervate Droplets as a Surfactant-Based Membrane-Free Protocell Model |
| Q54354286 | Cell-like systems with riboswitch controlled gene expression. |
| Q34310276 | Chain-length heterogeneity allows for the assembly of fatty acid vesicles in dilute solutions |
| Q39265302 | Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems. |
| Q41469073 | Chemical systems, chemical contiguity and the emergence of life |
| Q64921156 | Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA. |
| Q57817032 | Circular RNAs as Therapeutic Agents and Targets |
| Q38618425 | Compartmentalization Approaches in Soft Matter Science: From Nanoreactor Development to Organelle Mimics |
| Q90246452 | Compositional heterogeneity confers selective advantage to model protocellular membranes during the origins of cellular life |
| Q34239016 | Computer simulation on the cooperation of functional molecules during the early stages of evolution |
| Q36489375 | Concentration-driven growth of model protocell membranes |
| Q37762071 | Constructing partial models of cells. |
| Q27335361 | Controlled growth of filamentous fatty acid vesicles under flow |
| Q57970134 | Copying of Mixed-Sequence RNA Templates inside Model Protocells |
| Q37160273 | Coupled Growth and Division of Model Protocell Membranes |
| Q30513903 | Coupling of the fusion and budding of giant phospholipid vesicles containing macromolecules. |
| Q47399962 | Creation of Simple Biochemical Systems to Study Early Cellular Life |
| Q47134655 | Crude phosphorylation mixtures containing racemic lipid amphiphiles self-assemble to give stable primitive compartments. |
| Q28085556 | Current Ideas about Prebiological Compartmentalization |
| Q37785504 | DNA Ends: Just the Beginning (Nobel Lecture) |
| Q64066423 | DNA Length-dependent Division of a Giant Vesicle-based Model Protocell |
| Q92716988 | DNA polymerase activity on synthetic N3'→P5' phosphoramidate DNA templates |
| Q48480234 | Darwin's warm little pond revisited: from molecules to the origin of life |
| Q61207757 | Darwinian evolution in a translation-coupled RNA replication system within a cell-like compartment |
| Q22066168 | Definition of Life: Navigation through Uncertainties |
| Q43084442 | Design and synthesis of nucleolipids as possible activated precursors for oligomer formation via intramolecular catalysis: stability study and supramolecular organization |
| Q34219780 | Designs for life: protocell models in the laboratory. |
| Q99412304 | Dynamics of the vesicles composed of fatty acids and other amphiphile mixtures: unveiling the role of fatty acids as a model protocell membrane |
| Q33803394 | Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication |
| Q48311730 | Effect of terminal 3'-hydroxymethyl modification of an RNA primer on nonenzymatic primer extension |
| Q33503818 | Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers |
| Q84583419 | Efficient enzyme-free copying of all four nucleobases templated by immobilized RNA |
| Q48249917 | Encapsulation of Nucleic Acids into Giant Unilamellar Vesicles by Freeze-Thaw: a Way Protocells May Form. |
| Q91901063 | Encapsulation of hydrophobic components in dendrimersomes and decoration of their surface with proteins and nucleic acids |
| Q47613189 | Energy transduction inside of amphiphilic vesicles: encapsulation of photochemically active semiconducting particles. |
| Q38141058 | Evolving protocells to prototissues: rational design of a missing link |
| Q34101368 | Expanding roles for diverse physical phenomena during the origin of life |
| Q38945428 | Experiments on and Numerical Modeling of the Capture and Concentration of Transcription-Translation Machinery inside Vesicles |
| Q37853120 | Exploring the role of chirality in nucleic acid recognition. |
| Q37276593 | Fast and accurate nonenzymatic copying of an RNA-like synthetic genetic polymer |
| Q87876273 | Fatty Acid/Phospholipid Blended Membranes: A Potential Intermediate State in Protocellular Evolution |
| Q59576279 | Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model |
| Q30488834 | Formation of protocell-like vesicles in a thermal diffusion column |
| Q41147824 | Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research. |
| Q41235050 | Freeze-thaw cycles as drivers of complex ribozyme assembly |
| Q39428469 | From formamide to RNA, the path is tenuous but continuous |
| Q24630809 | From self-assembled vesicles to protocells |
| Q99207739 | Functional and morphological adaptation in DNA protocells via signal processing prompted by artificial metalloenzymes |
| Q37175346 | Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension |
| Q42680197 | Generation of long RNA chains in water. |
| Q34280277 | Genetics first or metabolism first? The formamide clue |
| Q43071274 | Goethe's dream. Challenges and opportunities for synthetic biology |
| Q41964121 | Growth and division in a dynamic protocell model |
| Q47742657 | Heat flux across an open pore enables the continuous replication and selection of oligonucleotides towards increasing length |
| Q42291312 | Highly oriented photosynthetic reaction centers generate a proton gradient in synthetic protocells |
| Q24624724 | Historical development of origins research |
| Q64071442 | How Prebiotic Chemistry and Early Life Chose Phosphate |
| Q47145844 | Hydrothermal Microflow Technology as a Research Tool for Origin-of-Life Studies in Extreme Earth Environments |
| Q34118561 | Inkjet formation of unilamellar lipid vesicles for cell-like encapsulation |
| Q85090039 | Interaction energies between oxide surfaces and multiple phosphatidylcholine bilayers from extended-DLVO theory |
| Q83462807 | Interactions between catalysts and amphiphilic structures and their implications for a protocell model |
| Q33777789 | Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world |
| Q47906699 | Interfacial assembly of protein-polymer nano-conjugates into stimulus-responsive biomimetic protocells |
| Q33874383 | Intravesicle isothermal DNA replication |
| Q92636031 | Investigating Prebiotic Protocells for A Comprehensive Understanding of the Origins of Life: A Prebiotic Systems Chemistry Perspective |
| Q64244201 | Length-Selective Synthesis of Acylglycerol-Phosphates through Energy-Dissipative Cycling |
| Q33351929 | Lethal mutants and truncated selection together solve a paradox of the origin of life |
| Q28744658 | Links between hydrothermal environments, pyrophosphate, na(+), and early evolution |
| Q55305521 | Lipid vesicles chaperone an encapsulated RNA aptamer. |
| Q46555502 | Liquid crystalline nanostructures: organizing matrices for non-enzymatic nucleic acid polymerization |
| Q55470943 | Macromolecularly Crowded Protocells from Reversibly Shrinking Monodisperse Liposomes. |
| Q47251862 | Marginal stability in chemical systems and its relevance in the origin of life |
| Q54648013 | Marginally stable chemical systems as precursors of life. |
| Q41895126 | Mechanistic Insights into Two-Phase Radical C-H Arylations |
| Q37777268 | Membrane Transport in Primitive Cells |
| Q47759106 | Microfluidic formation of proteinosomes. |
| Q34192348 | Microfluidic landscapes for evolution |
| Q48235869 | Microviscosity, encapsulation, and permeability of 2-ketooctanoic acid vesicle membranes. |
| Q93089164 | Mimicking Cellular Compartmentalization in a Hierarchical Protocell through Spontaneous Spatial Organization |
| Q37684103 | Mineral Surface Chemistry and Nanoparticle-aggregation Control Membrane Self-Assembly. |
| Q62629919 | Minimal cell mimicry |
| Q37885887 | Minimal cells: relevance and interplay of physical and biochemical factors. |
| Q37462218 | Model protocells from single-chain lipids |
| Q40487118 | Model systems of precursor cellular membranes: long-chain alcohols stabilize spontaneously formed oleic acid vesicles |
| Q28649901 | Molecular complementarity between simple, universal molecules and ions limited phenotype space in the precursors of cells |
| Q38259273 | Molecular crowding shapes gene expression in synthetic cellular nanosystems |
| Q38180601 | Molecular tools for the construction of peptide-based materials. |
| Q53382458 | Monoacylglycerols as transmembrane Cl- anion transporters. |
| Q38078444 | Motility at the origin of life: its characterization and a model |
| Q46938417 | Multifunctional porous microspheres based on peptide-porphyrin hierarchical co-assembly |
| Q27335304 | Multilevel selection in models of prebiotic evolution II: a direct comparison of compartmentalization and spatial self-organization |
| Q46446733 | N-Carboxyanhydride-Mediated Fatty Acylation of Amino Acids and Peptides for Functionalization of Protocell Membranes |
| Q33402610 | N2'-->p3' phosphoramidate glycerol nucleic acid as a potential alternative genetic system |
| Q42747999 | Natural - synthetic - artificial! |
| Q28076481 | Natural pH Gradients in Hydrothermal Alkali Vents Were Unlikely to Have Played a Role in the Origin of Life |
| Q38992239 | New evolutionary insights into the non-enzymatic origin of RNA oligomers |
| Q36179358 | Non-Enzymatic Oligomerization of 3', 5' Cyclic AMP |
| Q37625103 | Non-natural nucleic acids for synthetic biology |
| Q40226825 | Nonenzymatic Oligomerization of 3',5'-Cyclic CMP Induced by Proton and UV Irradiation Hints at a Nonfastidious Origin of RNA. |
| Q92629293 | Nonenzymatic Template-Directed Synthesis of Mixed-Sequence 3'-NP-DNA up to 25 Nucleotides Long Inside Model Protocells |
| Q46242768 | Nucleic acids: function and potential for abiogenesis |
| Q37103934 | Nucleobases bind to and stabilize aggregates of a prebiotic amphiphile, providing a viable mechanism for the emergence of protocells. |
| Q57499617 | On RAF Sets and Autocatalytic Cycles in Random Reaction Networks |
| Q37719044 | Open questions on the origin of life at anoxic geothermal fields |
| Q43514933 | Optically controlled pore formation in self-sealing giant porphyrin vesicles |
| Q42999235 | Organelle-mimicking liposome dissociates G-quadruplexes and facilitates transcription |
| Q37679855 | Origin and evolution of transporter substrate specificity within the NPF family |
| Q24595894 | Origin of evolution versus origin of life: a shift of paradigm |
| Q22066268 | Origin of first cells at terrestrial, anoxic geothermal fields |
| Q47673908 | Origins of life: How leaky were primitive cells? |
| Q37625108 | Peptide membranes in chemical evolution. |
| Q84808193 | Peptide-nucleotide microdroplets as a step towards a membrane-free protocell model |
| Q33784676 | Permeability-driven selection in a semi-empirical protocell model: the roots of prebiotic systems evolution |
| Q26779598 | Phenotypic Novelty in EvoDevo: The Distinction Between Continuous and Discontinuous Variation and Its Importance in Evolutionary Theory |
| Q30517945 | Photochemically driven redox chemistry induces protocell membrane pearling and division |
| Q39429444 | Physical Routes to Primitive Cells: An Experimental Model Based on the Spontaneous Entrapment of Enzymes inside Micrometer-Sized Liposomes. |
| Q34750165 | Physical effects underlying the transition from primitive to modern cell membranes |
| Q41851361 | Piecing Together Cell-like Systems |
| Q28728260 | Polycyclic aromatic hydrocarbons as plausible prebiotic membrane components |
| Q41851066 | Prebiotic chemistry: a new modus operandi |
| Q41058413 | Prebiotic selection for motifs in a model of template-free elongation of polymers within compartments. |
| Q36005625 | Prebiotic synthesis of nucleic acids and their building blocks at the atomic level - merging models and mechanisms from advanced computations and experiments |
| Q57376585 | Preparation of water-dispersible silver-decorated polymer vesicles and micelles with excellent antibacterial efficacy |
| Q55096492 | Preparation, Purification, and Use of Fatty Acid-containing Liposomes. |
| Q89790947 | Primary cell wall inspired micro containers as a step towards a synthetic plant cell |
| Q24604873 | Primitive genetic polymers |
| Q52371408 | Primordial sex facilitates the emergence of evolution. |
| Q39788698 | Probing of molecular replication and accumulation in shallow heat gradients through numerical simulations |
| Q38019717 | Programmable bacterial catalysis - designing cells for biosynthesis of value-added compounds. |
| Q90220693 | Progress in synthesizing protocells |
| Q38194195 | Progress toward synthetic cells |
| Q47580137 | Protein-mediated selective enclosure of early replicators inside of membranous vesicles: first step towards cell membranes |
| Q46249690 | Proton gradients and pH oscillations emerge from heat flow at the microscale |
| Q30383208 | Revealing the mechanism of passive transport in lipid bilayers via phonon-mediated nanometre-scale density fluctuations. |
| Q48256203 | Rewarming the Primordial Soup: Revisitations and Rediscoveries in Prebiotic Chemistry. |
| Q28487869 | Selection for replicases in protocells |
| Q55689892 | Self-Assembly Mechanism of a Peptide-Based Drug Delivery Vehicle. |
| Q42132033 | Self-Reproduction of Fatty Acid Vesicles: A Combined Experimental and Simulation Study |
| Q51073061 | Self-assembling cages from coiled-coil peptide modules. |
| Q34218691 | Self-reproduction of supramolecular giant vesicles combined with the amplification of encapsulated DNA. |
| Q64948396 | Sequence information transfer using covalent template-directed synthesis. |
| Q51472319 | Sequestration of Proteins by Fatty Acid Coacervates for Their Encapsulation within Vesicles. |
| Q52314793 | Ship in a bottle: confinement-promoted self-assembly. |
| Q38121763 | Single vesicle biochips for ultra-miniaturized nanoscale fluidics and single molecule bioscience |
| Q40486325 | Single-step fabrication of multi-compartmentalized biphasic proteinosomes. |
| Q47274794 | Spontaneous crowding of ribosomes and proteins inside vesicles: a possible mechanism for the origin of cell metabolism. |
| Q38270482 | Spontaneous encapsulation and concentration of biological macromolecules in liposomes: an intriguing phenomenon and its relevance in origins of life |
| Q53047843 | Spontaneous growth and division in self-reproducing inorganic colloidosomes. |
| Q53067141 | Spontaneous structuration in coacervate-based protocells by polyoxometalate-mediated membrane assembly. |
| Q99616794 | Stability and robustness of asymptotic autocatalytic systems |
| Q30498327 | Stepwise synthesis of giant unilamellar vesicles on a microfluidic assembly line |
| Q57369347 | Stimuli-responsive polymersomes and nanoreactors |
| Q34247938 | Stochastic simulations of minimal cells: the Ribocell model. |
| Q30845087 | Structural insights into RNA duplexes with multiple 2΄-5΄-linkages |
| Q42747290 | Sugar synthesis in a protocellular model leads to a cell signalling response in bacteria |
| Q36498132 | Sustainable proliferation of liposomes compatible with inner RNA replication |
| Q33926504 | Synthesis and nonenzymatic template-directed polymerization of 2'-amino-2'-deoxythreose nucleotides |
| Q41907134 | Synthesis of N3'-P5'-linked phosphoramidate DNA by nonenzymatic template-directed primer extension |
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