Targeting Toxoplasma tubules: tubulin, microtubules, and associated proteins in a human pathogen

scientific article

Targeting Toxoplasma tubules: tubulin, microtubules, and associated proteins in a human pathogen is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1128/EC.00225-14
P8608Fatcat IDrelease_qmxtl5suxffejck72i43wnh2ee
P932PMC publication ID4279016
P698PubMed publication ID25380753

P50authorNaomi S MorrissetteQ87723648
P2860cites workCytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondiiQ21559517
MEC-17 is an alpha-tubulin acetyltransferaseQ24299301
Structures of Toxoplasma gondii tachyzoites, bradyzoites, and sporozoites and biology and development of tissue cysts.Q24520491
Unique properties of Drosophila spermatocyte primary ciliaQ24599315
Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasitesQ25257149
Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite.Q27313989
Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagellaQ27318477
Organizational changes of the daughter basal complex during the parasite replication of Toxoplasma gondiiQ27319306
Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the Toxoplasma gondii pellicleQ27325755
Disruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assayQ27333124
The 3D structure of the apical complex and association with the flagellar apparatus revealed by serial TEM tomography in Psammosa pacifica, a distant relative of the ApicomplexaQ27334954
Dynein light chain 8a of Toxoplasma gondii, a unique conoid-localized β-strand-swapped homodimer, is required for an efficient parasite growthQ27683585
Functional dissection of the apicomplexan glideosome molecular architectureQ27972708
Novel thioredoxin-like proteins are components of a protein complex coating the cortical microtubules of Toxoplasma gondiiQ27973671
SPM1 stabilizes subpellicular microtubules in Toxoplasma gondiiQ27973682
Alveolins, a new family of cortical proteins that define the protist infrakingdom AlveolataQ27974699
Cep164 mediates vesicular docking to the mother centriole during early steps of ciliogenesisQ28000119
Inhibition of Toxoplasma gondii replication by dinitroaniline herbicidesQ42552114
Regulation of microtubule motors by tubulin isotypes and post-translational modificationsQ42760701
Ultrastructural studies on the sporulation of oocysts of Toxoplasma gondii. II. Formation of the sporocyst and structure of the sporocyst wallQ43503616
DNA replication and daughter cell budding are not tightly linked in the protozoan parasite Toxoplasma gondiiQ43615024
Disruption of microtubules uncouples budding and nuclear division in Toxoplasma gondiiQ43899687
Ciliary secretion: switching the cellular antenna to 'transmit'.Q44789462
TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.Q45967113
Induction and regulation of conoid extrusion in Toxoplasma gondii.Q46025109
Organellar dynamics during the cell cycle of Toxoplasma gondii.Q46645614
Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitroQ46987459
Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindleQ47846165
Characterization of the subpellicular network, a filamentous membrane skeletal component in the parasite Toxoplasma gondiiQ47885307
The cruciated microtubule-associated fibers of the green alga Dunaliella bioculata consist of a 31 kDa SF-assemblin.Q48065240
Tissue-specific microtubule functions in Drosophila spermatogenesis require the beta 2-tubulin isotype-specific carboxy terminusQ48113337
The α- and β-tubulins of Toxoplasma gondii are encoded by single copy genes containing multiple intronsQ48321471
Ciliate pellicular proteome identifies novel protein families with characteristic repeat motifs that are common to alveolatesQ50122602
Golgi and centrosome cycles in Toxoplasma gondii.Q50748763
Binding and interaction of dinitroanilines with apicomplexan and kinetoplastid alpha-tubulin.Q51144903
Kinetics and regulation of de novo centriole assembly. Implications for the mechanism of centriole duplication.Q52137805
Morphostasis in alveolate evolutionQ56038566
ToxoplasmosisQ56768394
Subpellicular microtubules associate with an intramembranous particle lattice in the protozoan parasite Toxoplasma gondiiQ59178757
Cytology and Kinetics of microgametogenesis and fertilization in Plasmodium yoelii nigeriensisQ66914441
Ultrastructural Study of Schizogony ofEimeria bovisin Cell Cultures*Q66994158
Ultrastructural studies on the sporulation of oocysts of Toxoplasma gondii. I. Development of the zygote and formation of the sporoblastsQ67019022
The ultrastructural development of the macrogamete and formation of the oocyst wall of Toxoplasma gondiiQ67319940
Fine structure of macrogametes and oocysts of Coccidia and related organismsQ68628596
Cytoskeleton of Toxoplasma gondiiQ69029546
Heat-stable microtubule protein MAP-1 binds to microtubules and induces microtubule assemblyQ70387486
Electron microscopical studies on the microgametogeny of Toxoplasma gondiiQ70633261
The polar ring of coccidian sporozoites: a unique microtubule-organizing centreQ71327567
Endopolygeny in Toxoplasma gondiiQ71784974
Microtubule structure at 8 A resolutionQ78364964
Ultrastructural differentiation of Toxoplasma gondii schizonts (types B to E) and gamonts in the intestines of cats fed bradyzoitesQ81400391
Optimisation of conoidin A, a peroxiredoxin inhibitorQ84962796
Towards elucidating the tubulin codeQ87583424
The tubulin fraternity: alpha to etaQ28143419
More than one way to build a flagellum: comparative genomics of parasitic protozoaQ28275846
Microtubules, but not actin filaments, drive daughter cell budding and cell division in Toxoplasma gondiiQ28372480
The primary cilium: a signalling centre during vertebrate developmentQ29547197
Kinesin superfamily motor proteins and intracellular transportQ29615770
Kinesin and dynein superfamily proteins and the mechanism of organelle transportQ29620418
An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmissionQ30039505
The Toxoplasma gondii kinetochore is required for centrosome association with the centrocone (spindle pole)Q30353434
A family of intermediate filament-like proteins is sequentially assembled into the cytoskeleton of Toxoplasma gondiiQ30497699
Targeted proteomic dissection of Toxoplasma cytoskeleton sub-compartments using MORN1.Q30534780
Toxoplasma gondii myosin F, an essential motor for centrosomes positioning and apicoplast inheritance.Q30540599
A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar componentsQ30541052
The Toxoplasma gondii centrosome is the platform for internal daughter budding as revealed by a Nek1 kinase mutantQ30542001
The cilium secretes bioactive ectosomesQ30558636
Evidence of intraflagellar transport and apical complex formation in a free-living relative of the apicomplexaQ30570497
Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondiiQ33320191
Freeze fracture study of Toxoplasma and Sarcocystis infective stages (author's transl)Q33366139
TgICMAP1 is a novel microtubule binding protein in Toxoplasma gondiiQ33510162
Post-translational modifications to Toxoplasma gondii alpha- and beta-tubulins include novel C-terminal methylationQ33514732
Cytoskeleton assembly in Toxoplasma gondii cell divisionQ33789466
Genome-wide analysis reveals novel and discrete functions for tubulin carboxy-terminal tailsQ33804686
Origin and evolution of the centrosomeQ33845372
Daughter cell assembly in the protozoan parasite Toxoplasma gondiiQ33953731
The centrosome in vertebrates: more than a microtubule-organizing centerQ33954846
Cytoskeleton of apicomplexan parasitesQ33969437
Basal bodies and centrioles: their function and structureQ34044939
Three-dimensional structure of basal body triplet revealed by electron cryo-tomographyQ34096396
Reconstructing the evolutionary history of the centriole from protein componentsQ34109956
The flagellum in malarial parasites.Q34121923
Sexual development in Plasmodium: lessons from functional analysesQ34139930
Toxoplasma gondii sequesters centromeres to a specific nuclear region throughout the cell cycleQ34164615
Post-translational modifications of microtubulesQ34182922
Building the CentrioleQ34205722
Epsilon-tubulin is an essential component of the centriole.Q34274317
Structure of a kinesin microtubule depolymerization machine.Q37544274
What tubulin drugs tell us about microtubule structure and dynamicsQ37946075
Towards a molecular architecture of centriole assemblyQ38018198
A Comparative Overview of the Flagellar Apparatus of Dinoflagellate, Perkinsids and ColpodellidsQ38970267
Proteomic characterization of the subpellicular cytoskeleton of Toxoplasma gondii tachyzoites.Q39224129
Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivativesQ39699060
Dinitroaniline activity in Toxoplasma gondii expressing wild-type or mutant alpha-tubulin.Q39895071
The functional analysis of the flagellar apparatus in green algae.Q40254673
Ca(2+)-dependence of conoid extrusion in Toxoplasma gondii tachyzoitesQ41222050
Molecular architecture of axonemal microtubule doublets revealed by cryo-electron tomographyQ41626017
GAP45 phosphorylation controls assembly of the Toxoplasma myosin XIV complex.Q42132434
IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II.Q42135439
SF-assemblin, the structural protein of the 2-nm filaments from striated microtubule associated fibers of algal flagellar roots, forms a segmented coiled coilQ42511819
Centrosomes: Sfi1p and centrin unravel a structural riddleQ34288555
In search of a function for centrinsQ34290900
Protist tubulins: new arrivals, evolutionary relationships and insights to cytoskeletal functionQ34331549
In vitro analysis of microtubule assembly of isotypically pure tubulin dimers. Intrinsic differences in the assembly properties of alpha beta II, alpha beta III, and alpha beta IV tubulin dimers in the absence of microtubule-associated proteins.Q34348695
RNG1 is a late marker of the apical polar ring in Toxoplasma gondiiQ34388105
Review: tubulin function, action of antitubulin drugs, and new drug developmentQ34425460
α-Tubulin mutations alter oryzalin affinity and microtubule assembly properties to confer dinitroaniline resistanceQ34432289
Speculations on the evolution of 9+2 organelles and the role of central pair microtubulesQ34552900
The apical complex provides a regulated gateway for secretion of invasion factors in ToxoplasmaQ35152152
Building the perfect parasite: cell division in apicomplexaQ35865647
Discovery of a novel Toxoplasma gondii conoid-associated protein important for parasite resistance to reactive nitrogen intermediates.Q35873964
A 60-kDa plant microtubule-associated protein promotes the growth and stabilization of neurotubules in vitroQ36135576
Mutations in alpha-tubulin confer dinitroaniline resistance at a cost to microtubule functionQ36173890
Centriole replication. II. Sperm formation in the fern, Marsilea, and the cycad, ZamiaQ36187923
Flagellar motion and fine structure of the flagellar apparatus in ChlamydomonasQ36188796
The plastid of Toxoplasma gondii is divided by association with the centrosomesQ36293658
Identification of the membrane receptor of a class XIV myosin in Toxoplasma gondiiQ36322129
A novel polymer of tubulin forms the conoid of Toxoplasma gondiiQ36324421
The Vfl1 Protein in Chlamydomonas localizes in a rotationally asymmetric pattern at the distal ends of the basal bodiesQ36342412
Electron microscope studies of microgametogenesis in coccidia and related groupsQ36522771
Electron microscope study of the proliferative form of Besnoitia jellisoniQ36538383
The dynein family at a glanceQ36639357
Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms.Q36709382
Microtubule-organizing centres: a re-evaluation.Q36716438
Microtubule assembly of isotypically purified tubulin and its mixturesQ36791183
Structure and duplication of the centrosomeQ36860079
The UNI3 gene is required for assembly of basal bodies of Chlamydomonas and encodes delta-tubulin, a new member of the tubulin superfamilyQ36872969
The tubulin codeQ36929344
Secondary mutations correct fitness defects in Toxoplasma gondii with dinitroaniline resistance mutationsQ36936842
ε-tubulin is essential in Tetrahymena thermophila for the assembly and stability of basal bodiesQ37061538
Dinitroanilines bind alpha-tubulin to disrupt microtubulesQ37221164
A new model for binding of kinesin 13 to curved microtubule protofilamentsQ37237869
Ixabepilone: targeting betaIII-tubulin expression in taxane-resistant malignanciesQ37367110
P433issue1
P304page(s)2-12
P577publication date2014-11-07
P1433published inEukaryotic CellQ5408685
P1476titleTargeting Toxoplasma tubules: tubulin, microtubules, and associated proteins in a human pathogen
P478volume14

Reverse relations

cites work (P2860)
Q47387133'Disc-o-Fever': Getting Down with Giardia's Groovy Microtubule Organelle
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Q88954728Microtubules and Microtubule-Associated Proteins
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Q37143055The Ubiquitin Proteome of Toxoplasma gondii Reveals Roles for Protein Ubiquitination in Cell-Cycle Transitions
Q39057811Towards a molecular architecture of the centrosome in Toxoplasma gondii

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