Physiological mechanisms regulating the expression of endothelial-type NO synthase.

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Physiological mechanisms regulating the expression of endothelial-type NO synthase. is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S1089-8603(02)00127-1
P698PubMed publication ID12223183

P50authorHuige LiQ41534843
P2093author name stringUlrich Förstermann
Thomas Wallerath
P2860cites workExpression and distribution of NOS1 and NOS3 in the myocardium of angiotensin II-infused ratsQ74026229
Shear stress regulation of endothelial NOS in fetal pulmonary arterial endothelial cells involves PKCQ74129533
Shear level influences resistance artery remodeling: wall dimensions, cell density, and eNOS expressionQ74403736
Endothelial NO synthase is increased in regenerating endothelium after denuding injury of the rat aortaQ77133241
Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPaseQ77195720
Endothelin-1 in the rat bile duct ligation model of hepatopulmonary syndrome: correlation with pulmonary dysfunctionQ77585948
Limb reduction defects in endothelial nitric oxide synthase-deficient miceQ77649735
Modulation of constitutive nitric oxide synthase, bcl-2 and Fas expression in cultured human coronary endothelial cells exposed to anoxia-reoxygenation and angiotensin II: role of AT1 receptor activationQ77746011
Endothelial nitric oxide synthase (eNOS) is localized to Müller cells in all vertebrate retinasQ77875719
Induction of nitric oxide synthase mRNA by shear stress requires intracellular calcium and G-protein signals and is modulated by PI 3 kinaseQ77911676
Evidence that an endothelial cytosolic protein binds to the 3'-untranslated region of endothelial nitric oxide synthase mRNAQ77960098
VEGF-A induces expression of eNOS and iNOS in endothelial cells via VEGF receptor-2 (KDR)Q22008505
A novel function of VEGF receptor-2 (KDR): rapid release of nitric oxide in response to VEGF-A stimulation in endothelial cellsQ22010936
Rho GTPases and the actin cytoskeletonQ27860579
Regulation of endothelial nitric oxide synthase expression by albumin-derived advanced glycosylation end productsQ28144967
Molecular cloning and characterization of human endothelial nitric oxide synthaseQ28187817
Functional analysis of the human endothelial nitric oxide synthase promoter. Sp1 and GATA factors are necessary for basal transcription in endothelial cellsQ28288107
Characterization of the human endothelial nitric-oxide synthase promoterQ28294946
Inotropic response to beta-adrenergic receptor stimulation and anti-adrenergic effect of ACh in endothelial NO synthase-deficient mouse heartsQ28365489
Regulation of endothelial nitric oxide synthase by PGD(2) in the developing choroidQ28369083
Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxideQ28370621
Endogenous endothelial cell nitric-oxide synthase modulates apoptosis in cultured breast cancer cells and is transcriptionally regulated by p53Q28377993
Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signalingQ28583271
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodelingQ28592810
Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoformQ30990194
Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthaseQ31172360
Up-regulation of endothelial nitric-oxide synthase promoter by the phosphatidylinositol 3-kinase gamma /Janus kinase 2/MEK-1-dependent pathwayQ31478590
Exercise training in coronary artery disease and coronary vasomotionQ31797073
Nitric oxide donors regulate nitric oxide synthase in bovine pulmonary artery endotheliumQ31809877
Short-term exercise training increases ACh-induced relaxation and eNOS protein in porcine pulmonary arteriesQ31959636
Cerivastatin prevents tumor necrosis factor-alpha-induced downregulation of endothelial nitric oxide synthase: role of endothelial cytosolic proteinsQ32062993
Antioxidants and oxidative stress in exerciseQ33796874
The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia.Q33834815
A vascular bed-specific pathway.Q33844643
Nitric oxide-angiotensin II interactions in angiotensin II-dependent hypertensionQ33848417
Lessons learned from nitric oxide synthase knockout animalsQ33858439
Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitorsQ34463540
Neuroprotection mediated by changes in the endothelial actin cytoskeleton.Q35128290
Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticityQ35221613
Dysfunctional regulation of endothelial nitric oxide synthase (eNOS) expression in response to exercise in mice lacking one eNOS geneQ43636915
Thrombin suppresses endothelial nitric oxide synthase and upregulates endothelin-converting enzyme-1 expression by distinct pathways: role of Rho/ROCK and mitogen-activated protein kinaseQ43750913
Activation of estrogen receptor beta is a prerequisite for estrogen-dependent upregulation of nitric oxide synthases in neonatal rat cardiac myocytesQ43754105
TCV-116 stimulates eNOS and caveolin-1 expression and improves coronary microvascular remodeling in normotensive and angiotensin II-induced hypertensive ratsQ43754542
Coronary artery endothelial protection after local delivery of 17beta-estradiol during balloon angioplasty in a porcine model: a potential new pharmacologic approach to improve endothelial functionQ43787233
Expression of an endothelial-type nitric oxide synthase isoform in human neutrophils: modification by tumor necrosis factor-alpha and during acute myocardial infarctionQ43788595
Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathwaysQ43805171
Changes in NOS activity and protein expression during acute and prolonged ANG II administrationQ43822317
Activation of type III nitric oxide synthase in astrocytes following a neurotropic viral infectionQ44226366
Evidence for the involvement of endothelial nitric oxide synthase from smooth muscle cells in the erectile function of the human corpus cavernosumQ47957563
Constitutive endothelial nitric oxide synthase (ecNOS) gene expression in human monocytesQ47957693
Characterization of the murine endothelial nitric oxide synthase promoterQ47996846
Expression of constitutive endothelial nitric oxide synthase in human blood plateletsQ48076826
Cloning and structural characterization of the human endothelial nitric-oxide-synthase gene.Q48080753
Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis.Q48735848
Hormonal regulation of nitric oxide synthases and their cell-specific expression during follicular development in the rat ovaryQ48824972
Role of nitric oxide in the angiogenic response in vitro to basic fibroblast growth factor.Q52187528
Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial cell nitric oxide synthase: contributions of NOS isoforms to blood pressure and heart rate control.Q52535966
Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription.Q52541795
Training induces nonuniform increases in eNOS content along the coronary arterial tree.Q54022788
Interactions between nitric oxide and endothelin in the regulation of vascular tone of human resistance vessels in vivo.Q54047980
Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.Q54062879
Angiotensin II stimulates synthesis of endothelial nitric oxide synthase.Q54148281
Downregulation of endothelial constitutive nitric oxide synthase expression by lipopolysaccharide.Q54583287
Induction of calcium-dependent nitric oxide synthases by sex hormones.Q35404786
Regulation of bovine endothelial constitutive nitric oxide synthase by oxygenQ35767871
Endothelial nitric oxide synthase is expressed in cultured human bronchiolar epitheliumQ35824420
Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertensionQ36673341
Gene structure, polymorphism and mapping of the human endothelial nitric oxide synthase geneQ36674016
Isolation and chromosomal localization of the human endothelial nitric oxide synthase (NOS3) geneQ36674805
Cloning and characterization of murine endothelial constitutive nitric oxide synthaseQ36814566
Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginineQ36817052
Correction of hypertension by normalization of endothelial levels of fibroblast growth factor and nitric oxide synthase in spontaneously hypertensive rats.Q37278969
Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cellsQ37358571
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cellsQ37376612
Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in miceQ37379247
Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3.Q37382771
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cellsQ37416665
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cellsQ37628594
Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production.Q37630081
Molecular regulation of the bovine endothelial cell nitric oxide synthase by transforming growth factor-beta 1.Q38293150
Organization of the bovine gene encoding the endothelial nitric oxide synthaseQ38305636
Molecular cloning, characterization and expression of a nitric oxide synthase from porcine pulmonary artery endothelial cellsQ38347077
Endothelial cytosolic proteins bind to the 3' untranslated region of endothelial nitric oxide synthase mRNA: regulation by tumor necrosis factor alphaQ40023475
Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathwayQ40919226
Nitric oxide synthase expression in endothelial cells exposed to mechanical forcesQ41012900
Activation of protein kinase C alpha and/or epsilon enhances transcription of the human endothelial nitric oxide synthase gene.Q41045681
Estrogens increase transcription of the human endothelial NO synthase gene: analysis of the transcription factors involved.Q41065759
Nitric oxide synthase: expression of the endothelial, Ca2+/calmodulin-dependent isoform in human B and T lymphocytesQ41225309
Identification of an endothelial-like type III NO synthase in LLC-PK1 kidney epithelial cellsQ41507326
Low concentration of oxidized low-density lipoprotein and lysophosphatidylcholine upregulate constitutive nitric oxide synthase mRNA expression in bovine aortic endothelial cellsQ41665885
Chronic estrogen treatment increases levels of endothelial nitric oxide synthase protein in rat cerebral microvesselsQ41694750
cGMP-mediated negative-feedback regulation of endothelial nitric oxide synthase expression by nitric oxideQ41708864
Insulin-induced vasodilatation: physiology or pharmacology?Q41751475
Amphotericin B severely affects expression and activity of the endothelial constitutive nitric oxide synthase involving altered mRNA stabilityQ41870780
Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) geneQ42440266
Transcriptional regulation of endothelial nitric-oxide synthase by lysophosphatidylcholineQ42456169
Neuronal nitric oxide synthase is expressed in rat vascular smooth muscle cells: activation by angiotensin II in hypertensionQ42465261
Vascular endothelial growth factor up-regulates nitric oxide synthase expression in endothelial cellsQ42475818
Regulation of endothelial constitutive nitric oxide synthase by protein kinase C.Q42477136
Hypertension in mice lacking the gene for endothelial nitric oxide synthaseQ42478091
Transcriptional regulation of endothelial nitric-oxide synthase by an interaction between casein kinase 2 and protein phosphatase 2A.Q42480352
Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-lifeQ42483273
Expression of endothelial nitric oxide synthase by extravillous trophoblast cells in the human placentaQ42484206
Assembly and characterization of canine heart endothelial nitric oxide synthase cDNA and 5'-flanking sequence by homology (RT-)PCR cloningQ42607587
Effect of chronic insulin treatment on NO production and endothelium-dependent relaxation in aortae from established STZ-induced diabetic ratsQ43545487
Systemic vascular effects of thrombin and thrombin receptor activating peptide in ratsQ43588735
Characterization of a constitutive type III nitric oxide synthase in human U937 monocytic cells: stimulation by soluble CD23Q57221215
Aorta and Skeletal Muscle NO Synthase Expression in Experimental Heart FailureQ57312535
Immunohistochemical Localization of Endothelial Nitric Oxide Synthase in Human Testis, Epididymis, and Vas Deferens Suggests a Possible Role for Nitric Oxide in Spermatogenesis, Sperm Maturation, and Programmed Cell Death1Q57609080
Differential regulation of the constitutive and inducible nitric oxide synthase mRNA by lipopolysacchride treatment in vivo in the ratQ61712889
Characterization of an Upstream Enhancer Region in the Promoter of the Human Endothelial Nitric-oxide Synthase GeneQ61912404
Sustained Increase in Aortic Endothelial Nitric Oxide Synthase Expression In Vivo in a Model of Chronic High Blood FlowQ61912407
Estrogen receptor-alpha gene transfer into bovine aortic endothelial cells induces eNOS gene expression and inhibits cell migrationQ64380949
Immunohistochemical localization of nitric oxide synthase in normal human skin: expression of endothelial-type and inducible-type nitric oxide synthase in keratinocytesQ64450005
Expression of nitric oxide synthase III in human thyroid follicular cells: evidence for increased expression in hyperthyroidism.Q64910091
Hypotensive activity of fibroblast growth factorQ68066299
Human dermal fibroblasts produce nitric oxide and express both constitutive and inducible nitric oxide synthase isoformsQ71120708
Cyclic expression of endothelial nitric oxide synthase mRNA in the epithelial glands of human endometriumQ71511420
Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expressionQ71607436
Expression of nitric oxide synthase immunoreactivity by interstitial cells of the canine proximal colonQ71656845
Regulation of endothelial nitric oxide synthase mRNA, protein, and activity during cell growthQ71659349
Increased expression of endothelial constitutive nitric oxide synthase in rat aorta during pregnancyQ71663265
Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthaseQ71667001
Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytesQ71697103
Transcriptional induction of endothelial nitric oxide synthase type III by lysophosphatidylcholineQ71702928
Decreased constitutive hepatic nitric oxide synthase expression in secondary biliary fibrosis and its changes after Roux-en-Y choledocho-jejunostomy in the ratQ71766371
Expression of nitric oxide synthase by syncytiotrophoblast in human placental villiQ72097612
Characterization and localization of endothelial nitric oxide synthase using specific monoclonal antibodiesQ72105512
Thrombin-induced endothelium-dependent inhibition and direct activation of platelet-vessel wall interaction. Role of prostacyclin, nitric oxide, and thromboxane A2Q72415188
Posttranscriptional regulation of endothelial nitric oxide synthase during cell growthQ73041973
Renal expression of constitutive NOS and DDAH: separate effects of salt intake and angiotensinQ73108239
Nitric oxide (NO) upregulates NO synthase expression in fetal intrapulmonary artery endothelial cellsQ73118729
Potential functional significance of brain-type and muscle-type nitric oxide synthase I expressed in adventitia and media of rat aortaQ73175590
Differential induction of constitutive and inducible nitric oxide synthases by distinct inflammatory stimuli in bovine aortic endothelial cellsQ73215774
Shear stress induction of the endothelial nitric oxide synthase gene is calcium-dependent but not calcium-activatedQ73295550
Expression of endothelial nitric oxide synthase in the Sertoli cells of men with infertility of various causesQ73309305
17beta-estradiol restores endothelial nitric oxide release to shear stress in arterioles of male hypertensive ratsQ73318137
Increased endogenous nitric oxide production induced by physical exercise in peripheral arterial occlusive disease patientsQ73327038
Cell growth modulates nitric oxide synthase expression in fetal pulmonary artery endothelial cellsQ73381986
Transcriptional induction of endothelial nitric oxide gene by cyclosporine A. A role for activator protein-1Q73396461
Expression of nitric oxide synthase isoforms in bone and bone cell culturesQ73452011
Localization of the e-NOS enzyme in endothelial cells and odontoblasts of healthy human dental pulpQ73470898
17 Beta-estradiol stimulates expression of endothelial and inducible NO synthase in rat myocardium in-vitro and in-vivoQ73482875
Effect of insulin on human aortic endothelial nitric oxide synthaseQ73484100
Molecular basis of cell-specific endothelial nitric-oxide synthase expression in airway epitheliumQ73538522
Biliary cyst fluid from common bile duct-ligated rats stimulates endothelial nitric oxide synthase in pulmonary artery endothelial cells: a potential role in hepatopulmonary syndromeQ73568215
Expression of nitric oxide synthase isoforms in normal ventilatory and limb musclesQ73599369
Electron transfer, oxygen binding, and nitric oxide feedback inhibition in endothelial nitric-oxide synthaseQ73631005
Nitric oxide synthase isoform III gene expression in rat liver is up-regulated by lipopolysaccharide and lipoteichoic acidQ73641368
Expression of endothelial constitutive nitric oxide synthase mRNA in gastrointestinal mucosa and its downregulation by endotoxinQ73766428
Neuronal and endothelial nitric oxide synthase expression in outer medulla of streptozotocin-induced diabetic rat kidneyQ73899593
P433issue2
P921main subjectendotheliumQ111140
P304page(s)132-147
P577publication date2002-09-01
P1433published inNitric OxideQ7041392
P1476titlePhysiological mechanisms regulating the expression of endothelial-type NO synthase
P478volume7

Reverse relations

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