Ricin crosses polarized human intestinal cells and intestines of ricin-gavaged mice without evident damage and then disseminates to mouse kidneys

scientific article

Ricin crosses polarized human intestinal cells and intestines of ricin-gavaged mice without evident damage and then disseminates to mouse kidneys is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...869706F
P356DOI10.1371/JOURNAL.PONE.0069706
P932PMC publication ID3714305
P698PubMed publication ID23874986
P5875ResearchGate publication ID250926429

P2093author name stringMark A Smith
Alison D O'Brien
Angela R Melton-Celsa
Louise D Teel
James F Sinclair
Alyssa D Flora
P2860cites workRicin Toxicokinetics and Its Sensitive Detection in Mouse Sera or Feces Using Immuno-PCRQ33705099
Shiga toxins 1 and 2 translocate differently across polarized intestinal epithelial cellsQ34002866
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RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomesQ34163395
Inhibition of apical but not basolateral endocytosis of ricin and folate in Caco-2 cells by cytochalasin D.Q34317746
Ricin poisoning: a comprehensive reviewQ34651243
Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxicationQ34681058
Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxicationQ35783871
Castor bean intoxicationQ37973001
Oligosaccharide side chains on human secretory IgA serve as receptors for ricinQ38340964
Use of lactose against the deadly biological toxin ricinQ38345107
Binding of galactose and lactose to ricin. Equilibrium studiesQ38358023
RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosolQ39252241
A three-dimensional tissue culture model for the study of attach and efface lesion formation by enteropathogenic and enterohaemorrhagic Escherichia coliQ40347394
Estimation of the amount of internalized ricin that reaches the trans-Golgi networkQ41544514
Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium.Q41744752
Oxidative stress associated hepatic and renal toxicity induced by ricin in miceQ44301426
Biochemical studies on oral toxicity of ricin. IV. A fate of orally administered ricin in ratsQ44458491
Diet and abdominal autofluorescence detected by in vivo fluorescence imaging of living mice.Q47798223
Cultural and Antigenic Properties of Newly Established Cell Strains Derived From Adenocarcinomas of the Human Colon and RectumQ47872753
An in vivo model to study immunotoxin-induced vascular leak in human tissue.Q50520420
The establishment of strains of human cells in tissue culture.Q52831945
Retrospective identification of ricin in animal tissues following administration by pulmonary and oral routesQ83226925
Lethal ricin intoxication in two adult dogs: toxicologic and histopathologic findingsQ84189330
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)e69706
P577publication date2013-07-17
P1433published inPLOS OneQ564954
P1476titleRicin crosses polarized human intestinal cells and intestines of ricin-gavaged mice without evident damage and then disseminates to mouse kidneys
P478volume8

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cites work (P2860)
Q37285664A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response
Q59133328Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age
Q89552026Targeting Macromolecules to CNS and Other Hard-to-Treat Organs Using Lectin-Mediated Delivery

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