Cytosolic phospholipaseA2 inhibition with PLA-695 radiosensitizes tumors in lung cancer animal models.

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Cytosolic phospholipaseA2 inhibition with PLA-695 radiosensitizes tumors in lung cancer animal models. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...869688T
P356DOI10.1371/JOURNAL.PONE.0069688
P932PMC publication ID3716600
P698PubMed publication ID23894523
P5875ResearchGate publication ID253336621

P50authorRama P KotipatruniQ84742763
P2093author name stringDennis E Hallahan
Daniel J Ferraro
Jerry J Jaboin
Dinesh Thotala
Jeffrey M Craft
Sandeep R Bhave
P2860cites workThe confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation.Q52852938
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Tumor response to radiotherapy regulated by endothelial cell apoptosisQ73401346
Radiosensitization with carboplatin for patients with unresectable stage III non-small-cell lung cancer: a phase III trial of the Cancer and Leukemia Group B and the Eastern Cooperative Oncology GroupQ78160747
Cytosolic phospholipase A2 regulates viability of irradiated vascular endotheliumQ81486511
cPLA2 is phosphorylated and activated by MAP kinaseQ24314148
Modes of resistance to anti-angiogenic therapyQ24608005
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Postoperative adjuvant therapy for patients with resected non-small cell lung cancer: still controversial after all these yearsQ33897556
Cytosolic Phospholipase A2 and Lysophospholipids in Tumor AngiogenesisQ34145860
Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disordersQ34565668
Phospholipase A(2) isoforms: a perspectiveQ35125684
Mechanism of radiation-induced bystander effects: a unifying modelQ35541188
The Swedish Council on Technology Assessment in Health Care (SBU) Systematic Overview of Radiotherapy for Cancer including a Prospective Survey of Radiotherapy Practice in Sweden 2001--Summary and ConclusionsQ35574838
Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivoQ36246828
Advances in radiation oncology.Q36366796
Roles of cPLA2alpha and arachidonic acid in cancerQ36629023
Radiation-induced cell signaling: inside-out and outside-inQ36760964
Anastellin, the angiostatic fibronectin peptide, is a selective inhibitor of lysophospholipid signalingQ37135504
Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signalingQ37323724
Cytosolic phospholipase A2 as a mediator of disease pathogenesisQ37774040
Targeted agents in non-small cell lung cancer (NSCLC): clinical developments and rationale for the combination with thoracic radiotherapyQ37971168
Combining angiogenesis inhibition and radiotherapy: a double-edged swordQ38007807
Transactivation of fetal liver kinase-1/kinase-insert domain-containing receptor by lysophosphatidylcholine induces vascular endothelial cell proliferationQ40345232
Cytosolic phospholipase A2: targeting cancer through the tumor vasculatureQ40689319
Delayed oxidant-induced cell death involves activation of phospholipase A2.Q40762207
Induction of cPLA2 in lung epithelial cells and non-small cell lung cancer is mediated by Sp1 and c-JunQ40780263
Induction of cytosolic phospholipase A2 by oncogenic Ras in human non-small cell lung cancerQ41105606
Activation of cytosolic phospholipase A2-{alpha} as a novel mechanism regulating endothelial cell cycle progression and angiogenesisQ43177511
Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID miceQ43562373
A new link in ovarian cancer angiogenesis: lysophosphatidic acid and vascular endothelial growth factor expressionQ43608436
Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenesQ43716038
Cytosolic phospholipase A2-alpha and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatusQ45273421
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)e69688
P577publication date2013-07-19
P1433published inPLOS OneQ564954
P1476titleCytosolic phospholipaseA2 inhibition with PLA-695 radiosensitizes tumors in lung cancer animal models
P478volume8

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cites work (P2860)
Q35948220Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model
Q38179801Chemical modulation of glycerolipid signaling and metabolic pathways
Q35886245Cytosolic phospholipase A₂: physiological function and role in disease
Q92642416Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS)
Q46681431Platelet Lipidomic Profiling: Novel Insight into Cytosolic Phospholipase A2α Activity and Its Role in Human Platelet Activation
Q40181455Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation
Q39627791The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma

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