Local therapies for inflammatory eye disease in translation: past, present and future

scientific article

Local therapies for inflammatory eye disease in translation: past, present and future is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1051090491
P356DOI10.1186/1471-2415-13-39
P932PMC publication ID3750406
P698PubMed publication ID23914773
P5875ResearchGate publication ID255692070

P50authorSimon R. TaylorQ42590171
P2093author name stringAndrew D Dick
Lavnish Joshi
Shenzhen Tempest-Roe
P2860cites workInfliximab for chronic cystoid macular edema associated with uveitisQ80871601
Iluvien: a new sustained delivery technology for posterior eye diseaseQ81891397
intravitreal tumor necrosis factor inhibitors in the treatment of refractory diabetic macular edema: a pilot study from the Pan-American Collaborative Retina Study GroupQ82567912
Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical studyQ83321961
Intravitreal methotrexate in uveitisQ83799506
Intravitreal ketorolac for chronic uveitis and macular edema: a pilot studyQ83853998
Rituximab in refractory ophthalmic Wegener's granulomatosis: PR3 titers may predict relapse, but repeat treatment can be effectiveQ84929331
Efficacy and safety of intravitreal bevacizumab compared with intravitreal and posterior sub-tenon triamcinolone acetonide for treatment of uveitic cystoid macular edemaQ85057723
Repeat intravitreal triamcinolone acetonide injections in uveitic macular oedemaQ95386125
Interleukin 6 induces the expression of vascular endothelial growth factorQ24316308
Standardization of uveitis nomenclature for reporting clinical data. Results of the First International WorkshopQ24727581
The danger model: a renewed sense of selfQ28214633
Intravitreal injection of Tacrolimus (FK506) suppresses ongoing experimental autoimmune uveoretinitis in RatsQ28565470
Ranibizumab for neovascular age-related macular degenerationQ29617549
Randomized clinical trial of Surodex steroid drug delivery system for cataract surgery: anterior versus posterior placement of two Surodex in the eye.Q30717126
Intravitreal dexamethasone effectively reduces postoperative inflammation after vitreoretinal surgeryQ31142616
Randomized clinical trial of a new dexamethasone delivery system (Surodex) for treatment of post-cataract surgery inflammationQ31913255
Orbital floor triamcinolone acetonide injections for the management of active non-infectious uveitisQ33332567
Distinct cytokine and chemokine profiles in the aqueous of patients with uveitis and cystoid macular edemaQ79826333
Intravitreal bevacizumab for treatment of uveitic macular edemaQ79960243
Safety profile of intravitreal triamcinolone acetonideQ80530355
Comparison of orbital floor triamcinolone acetonide and oral prednisolone for cataract surgery management in patients with non-infectious uveitisQ33524839
Sustained ocular delivery of fluocinolone acetonide by an intravitreal insertQ33536900
What is new HLA-B27 acute anterior uveitis?Q34172654
Ocular neuroprotection by siRNA targeting caspase-2Q34192944
Road to fulfilment: taming the immune response to restore visionQ34259510
From beach to bedside: history of the development of sirolimusQ34395669
Developments in the treatment of uveitisQ34481964
Ranibizumab versus verteporfin for neovascular age-related macular degeneration.Q34652928
Intraocular methotrexate can induce extended remission in some patients in noninfectious uveitisQ34686335
Long-term, multicenter evaluation of subconjunctival injection of triamcinolone for non-necrotizing, noninfectious anterior scleritisQ35250540
Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: the multicenter uveitis steroid treatment trialQ35319079
Interplay between innate and adaptive immunity in the development of non-infectious uveitisQ35784059
A review of evidence guiding the use of corticosteroids in the treatment of intraocular inflammationQ35895945
The pros and cons of intravitreal triamcinolone injections for uveitis and inflammatory cystoid macular edema.Q36441711
Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE StudyQ36722548
Tumor necrosis factor antagonists: preliminary evidence for an emerging approach in the treatment of ocular inflammationQ36786463
Advances in the diagnosis and immunotherapy for ocular inflammatory diseaseQ37102197
International Uveitis Study Group (IUSG): clinical classification of uveitisQ37124620
P2X7 deficiency attenuates renal injury in experimental glomerulonephritisQ37211139
Assessment: the use of natalizumab (Tysabri) for the treatment of multiple sclerosis (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologyQ37259057
Penetration of topical and subconjunctival corticosteroids into human aqueous humour and its therapeutic significance.Q37416854
More questions than answers: a call for a moratorium on the use of intravitreal infliximab outside of a well-designed trialQ37487110
The use of intraocular corticosteroidsQ37598893
The NLRP3 inflammasome: a sensor for metabolic danger?Q37675505
Nonsteroidal anti-inflammatory drugs in ophthalmologyQ37693301
New developments in corticosteroid therapy for uveitisQ37780430
Cryopyrin-associated periodic syndrome: an update on diagnosis and treatment responseQ37811988
Cytomegalovirus endotheliitis after fluocinolone acetonide (Retisert) implant in a patient with Behçet uveitisQ37902663
Understanding uveitis: the impact of research on visual outcomesQ37909585
Review and update of intraocular therapy in noninfectious uveitisQ37928383
Difluprednate for inflammatory eye disordersQ37947609
A systematic review of the association of diabetic retinopathy and cognitive impairment in people with Type 2 diabetesQ37966386
Dexamethasone intravitreal implant for noninfectious intermediate or posterior uveitisQ38495949
SIRT1 activation protects against autoimmune T cell-driven retinal disease in mice via inhibition of IL-2/Stat5 signalingQ39470105
Efficacy of low-release-rate fluocinolone acetonide intravitreal implants to treat experimental uveitisQ40308355
Local cyclosporine therapy for experimental autoimmune uveitis in ratsQ41374533
Phase II results of an intraocular steroid delivery system for cataract surgeryQ41671762
Adverse events after intravitreal infliximab (Remicade).Q42642245
Intravitreal infliximab for the treatment of sight-threatening chronic noninfectious uveitis.Q42869100
Combination intravitreal rituximab and methotrexate for massive subretinal lymphomaQ42938838
Characterisation of systemic and ocular drug level of triamcinolone acetonide following a single sub-Tenon injectionQ43071562
Intravitreal triamcinolone for intraocular inflammation and associated macular edemaQ43096392
Intravitreal adalimumab for refractory uveitis-related macular edema.Q43105859
Intravitreal bevacizumab versus triamcinolone acetonide for refractory uveitic cystoid macular edema: a randomized pilot studyQ43122166
Combined fluocinolone acetonide intravitreal insertion and glaucoma drainage device placement for chronic uveitis and glaucomaQ43147543
Short-term results of a single intravitreal bevacizumab (avastin) injection versus a single intravitreal triamcinolone acetonide (kenacort) injection for the management of refractory noninfectious uveitic cystoid macular edemaQ43225838
Mathematical modeling of triamcinolone acetonide drug release from the I-vation intravitreal implant (a controlled release platform).Q43229029
Pilot study of intravitreal injection of diclofenac for treatment of macular edema of various etiologiesQ43232467
Intravitreal dexamethasone as adjuvant in the treatment of postoperative endophthalmitis: a prospective randomized trialQ43541201
Intravitreal VEGF levels in uveitis patients and treatment of uveitic macular oedema with intravitreal bevacizumabQ44570349
Infliximab for recurrent, sight-threatening ocular inflammation in Adamantiades-Behçet diseaseQ44783874
Ocular pharmacokinetics of fluocinolone acetonide after Retisert intravitreal implantation in rabbits over a 1-year periodQ44997164
Clinical trial to compare efficacy and side-effects of injection of posterior sub-Tenon triamcinolone versus orbital floor methylprednisolone in the management of posterior uveitisQ45170976
Vitreous concentrations of triamcinolone acetonide in human eyes after intravitreal or subtenon injectionQ45209421
Rituximab is effective in the treatment of refractory ophthalmic Wegener's granulomatosisQ45261256
Intravitreal triamcinolone for persistent cystoid macular oedema in eyes with quiescent uveitis.Q45931376
Intravitreal bevacizumab in refractory uveitic macular edema: one-year follow-up.Q45955518
Intravitreal and orbital floor triamcinolone acetonide injections in noninfectious uveitis: a comparative study.Q45991577
Ranibizumab for refractory uveitis-related macular edema.Q46018981
Intraocular methotrexate in the treatment of uveitis and uveitic cystoid macular edemaQ46062208
Evaluation of potential retinal toxicity of adalimumab (Humira).Q46083924
Complications and safety profile of posterior subtenon injection of triamcinolone acetonide.Q46089589
Effect of the macromolecular architecture of biodegradable polyurethanes on the controlled delivery of ocular drugsQ46318162
Fingolimod (FTY720) as an acute rescue therapy for intraocular inflammatory diseaseQ46318670
Pharmacokinetics and posterior segment biodistribution of ESBA105, an anti-TNF-alpha single-chain antibody, upon topical administration to the rabbit eye.Q46403637
Effects of intravitreal injection of tacrolimus (FK506) in experimental uveitisQ46425622
Efficacy and safety of 1% rimexolone versus 1% prednisolone acetate in the treatment of anterior uveitis--a randomized triple masked studyQ46451266
Combined fluocinolone acetonide intraocular delivery system insertion, phacoemulsification, and intraocular lens implantation for severe uveitisQ46474975
Outcome of intravitreal triamcinolone in uveitisQ46711026
Intravitreal bevacizumab (avastin) as a treatment for refractory macular edema in patients with uveitis: a pilot studyQ46815448
Intravitreal methotrexate as an adjunctive treatment of intraocular lymphoma.Q48627948
Cyclosporine-loaded microspheres for treatment of uveitis: in vitro characterization and in vivo pharmacokinetic study.Q51140243
Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8.Q54033436
Effect of infliximab on sight-threatening panuveitis in Behçet's disease.Q54153155
Rapamune® (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progressionQ57362835
Dexamethasone Implant in Pediatric UveitisQ57638955
Topical application of ciclosporin ophthalmic solution containing alpha-cyclodextrin in experimental uveitisQ67829506
Intraocular penetration of periocular ketorolac and efficacy in experimental uveitisQ70988225
The Effects of Posterior Subtenon Injection of Triamcinolone Acetonide in Patients With Intermediate UveitisQ71878418
Orbital floor steroid injections in the treatment of uveitisQ72020579
Role of intravitreal methotrexate in the management of primary central nervous system lymphoma with ocular involvementQ74710765
Aqueous humor and plasma vascular endothelial growth factor in uveitis-associated cystoid macular edemaQ77156632
Controlled evaluation of loteprednol etabonate and prednisolone acetate in the treatment of acute anterior uveitis. Loteprednol Etabonate US Uveitis Study GroupQ77766048
Intraocular methotrexate in ocular diseases other than primary central nervous system lymphomaQ79287102
P433issue1
P921main subjecteye diseaseQ3041498
P304page(s)39
P577publication date2013-08-06
P1433published inBMC OphthalmologyQ15765692
P1476titleLocal therapies for inflammatory eye disease in translation: past, present and future
P478volume13

Reverse relations

cites work (P2860)
Q34793097Antagonist of GH-releasing hormone receptors alleviates experimental ocular inflammation
Q37412317Birdshot uveitis: current and emerging treatment options
Q33849167Effects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis
Q48262834Green tea extract attenuates LPS-induced retinal inflammation in rats.
Q36273801In Vitro and In Vivo Sustained Zero-Order Delivery of Rapamycin (Sirolimus) From a Biodegradable Intraocular Device
Q104795267Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance
Q37609648Inhibitory effect of a novel peptide, H-RN, on keratitis induced by LPS or poly(I:C) in vitro and in vivo via suppressing NF-κB and MAPK activation
Q52338865Management of chronic ocular sarcoidosis: challenges and solutions.
Q38235720Ocular Involvement in Juvenile Idiopathic Arthritis: Classification and Treatment
Q92524802Outcomes Associated With Sustained-Release Intraocular Fluocinolone Implants in a Case of Melanoma-Associated Retinopathy Treated Without Systemic Immunosuppression
Q34274075Pharmacotherapy for uveitis: current management and emerging therapy
Q90403165Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach
Q35873681Risk of Retinal Neovascularization in Cases of Uveitis
Q91650696Safety and efficacy of tacrolimus-coated silicone plates as an alternative to mitomycin C in a rabbit model of conjunctival fibrosis
Q38397111Update on intravitreal anti-tumor necrosis factor alpha therapies for ocular disorders
Q37513981Uveitis as a Result of MAP Kinase Pathway Inhibition.

Search more.