scholarly article | Q13442814 |
P50 | author | Alberto Bardelli | Q28321691 |
Monica Rodolfo | Q37376562 | ||
Aldo Scarpa | Q37392347 | ||
P2093 | author name string | Antonio Marchetti | |
Fiamma Buttitta | |||
Francesca Molinari | |||
Lara Felicioni | |||
Milo Frattini | |||
Sara Malatesta | |||
Fonnet E Bleeker | |||
W Peter Vandertop | |||
Margaret Knowles | |||
Dirk Troost | |||
Sieger Leenstra | |||
Simona Lamba | |||
Aniello Cerrato | |||
Theo Hulsebos | |||
P2860 | cites work | The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase | Q22010653 |
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses | Q24606006 | ||
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The consensus coding sequences of human breast and colorectal cancers | Q27861035 | ||
The genomic landscapes of human breast and colorectal cancers | Q27861078 | ||
Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity | Q28116883 | ||
Cytosolic NADP(+)-dependent isocitrate dehydrogenase status modulates oxidative damage to cells | Q28589157 | ||
Genetic pathways to primary and secondary glioblastoma | Q35757144 | ||
DLD-1 and HCT-15 cell lines derived separately from colorectal carcinomas have totally different chromosome changes but the same genetic origin | Q38509007 | ||
Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma | Q40144627 | ||
Genetic pathways to glioblastoma: a population-based study | Q44673208 | ||
AKT1(E17K) in human solid tumours | Q46574533 | ||
P433 | issue | 1 | |
P304 | page(s) | 7-11 | |
P577 | publication date | 2009-01-01 | |
P1433 | published in | Human Mutation | Q5937269 |
P1476 | title | IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors | |
P478 | volume | 30 |
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Q36449844 | A population-based study of high-grade gliomas and mutated isocitrate dehydrogenase 1. |
Q48446221 | ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma |
Q30439629 | Absence of AKT1 mutations in glioblastoma |
Q34607312 | Absence of DICER1, CTCF, RPL22, DNMT3A, TRRAP, IDH1 and IDH2 hotspot mutations in patients with various subtypes of ovarian carcinomas |
Q42091501 | Absence of R140Q mutation of isocitrate dehydrogenase 2 in gliomas and breast cancers |
Q33782633 | Acute myeloid leukemia with IDH1 or IDH2 mutation: frequency and clinicopathologic features |
Q38014949 | Advances in malignant glioma drug discovery |
Q36608747 | Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention |
Q47131592 | An expression screen for aged-dependent microRNAs identifies miR-30a as a key regulator of aging features in human epidermis |
Q47356155 | Analysis of NADP+-dependent isocitrate dehydrogenase-1/2 gene mutations in pediatric brain tumors: report of a secondary anaplastic astrocytoma carrying the IDH1 mutation |
Q37015509 | Aspirin Reduces Plasma Concentrations of the Oncometabolite 2-Hydroxyglutarate: Results of a Randomized, Double-Blind, Crossover Trial |
Q38997694 | Association of The IDH1 C.395G>A (R132H) Mutation with Histological Type in Malay Brain Tumors |
Q36544617 | BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism. |
Q58766030 | Bridging Cancer Biology with the Clinic: Comprehending and Exploiting IDH Gene Mutations in Gliomas |
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Q37802750 | Cancer-associated IDH mutations: biomarker and therapeutic opportunities |
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Q35705274 | Cancer-associated isocitrate dehydrogenase mutations |
Q38757601 | Cancer-associated isocitrate dehydrogenase mutations induce mitochondrial DNA instability |
Q42141882 | Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations |
Q37390701 | Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations |
Q46054736 | Cancer. Puzzling patterns of predisposition |
Q64120431 | Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production |
Q39068086 | Clinicopathological features and molecular analysis of primary glioblastomas in Moroccan patients |
Q48579074 | Clinicopathological features of human brainstem gliomas |
Q36109794 | Clonal analysis in recurrent astrocytic, oligoastrocytic and oligodendroglial tumors implicates IDH1- mutation as common tumor initiating event |
Q36866028 | Comparative study of IDH1 mutations in gliomas by immunohistochemistry and DNA sequencing. |
Q55409347 | Concurrent IDH1 and SMARCB1 Mutations in Pediatric Medulloblastoma: A Case Report. |
Q34588501 | Correlation of MLH1 and MGMT expression and promoter methylation with genomic instability in patients with thyroid carcinoma |
Q33975580 | Demographic variation in incidence of adult glioma by subtype, United States, 1992-2007. |
Q38410050 | Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry |
Q41525199 | Detection of IDH1 and IDH2 mutations by fluorescence melting curve analysis as a diagnostic tool for brain biopsies |
Q28246788 | Determination of phosphate-activated glutaminase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry) |
Q43656999 | Diagnostic implications of IDH1-R132H and OLIG2 expression patterns in rare and challenging glioblastoma variants |
Q35441165 | Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma |
Q42042456 | Distribution bias analysis of germline and somatic single-nucleotide variations that impact protein functional site and neighboring amino acids |
Q38639828 | Driver mutations of cancer epigenomes. |
Q36558431 | Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma |
Q51327505 | Emerging drugs for biliary cancer. |
Q28395302 | Epidemiologic and molecular prognostic review of glioblastoma |
Q35705307 | Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping |
Q90025515 | Friend or foe-IDH1 mutations in glioma 10 years on |
Q64073085 | Functional analysis and clinical significance of the isocitrate dehydrogenase 2 gene in papillary thyroid carcinoma |
Q34647741 | Gene mutations and molecularly targeted therapies in acute myeloid leukemia. |
Q45946934 | Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients. |
Q60054025 | Genetics of Glioblastoma in Moroccan population: Review of literature |
Q34735661 | Glial progenitors as targets for transformation in glioma |
Q36225372 | Glioblastoma multiforme: Molecular characterization and current treatment strategy (Review). |
Q38411964 | Glioma cells showing IDH1 mutation cannot be propagated in standard cell culture conditions. |
Q29619709 | Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha |
Q38747962 | HOT mutation screening in human glioblastomas |
Q55463524 | High-throughput immunohistochemical profiling of primary brain tumors and non-neoplastic systemic organs with a specific antibody against the mutant isocitrate dehydrogenase 1 R132H protein. |
Q36737930 | Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas |
Q46244463 | IDH mutation status impact on in vivo hypoxia biomarkers expression: new insights from a clinical, nuclear imaging and immunohistochemical study in 33 glioma patients |
Q55462570 | IDH mutation status in prostate cancer. |
Q37778541 | IDH mutations in glioma and acute myeloid leukemia |
Q38022856 | IDH mutations in human glioma |
Q33615867 | IDH mutations: genotype-phenotype correlation and prognostic impact. |
Q55457146 | IDH1 Arg-132 mutant promotes tumor formation through down-regulating p53. |
Q41721821 | IDH1 R132H Mutation Is Accompanied with Malignant Progression of Paired Primary-Recurrent Astrocytic Tumours |
Q39568860 | IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo |
Q33709922 | IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway |
Q33897586 | IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study |
Q41137508 | IDH1 and IDH2 hotspot mutations are not found in canine glioma. |
Q43089505 | IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms. |
Q34562170 | IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis. |
Q42858887 | IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders |
Q24561928 | IDH1 and IDH2 mutations in gliomas |
Q38052534 | IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives |
Q54584786 | IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors. |
Q39506081 | IDH1 gene mutations: a new paradigm in glioma prognosis and therapy? |
Q58738690 | IDH1 is intrinsically tumor-suppressive but functionally attenuated by the glutamate-rich cerebral environment |
Q34458930 | IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group |
Q42164790 | IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas |
Q34603959 | IDH1 mutations in a Brazilian series of Glioblastoma. |
Q48404919 | IDH1 mutations in diffusely infiltrating astrocytomas: grade specificity, association with protein expression, and clinical relevance. |
Q37875253 | IDH1 mutations in gliomas: first series from a tertiary care centre in India with comprehensive review of literature |
Q34330224 | IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain |
Q38227739 | IDH1/2 mutation detection in gliomas |
Q33597773 | IDH1/IDH2 but not TP53 mutations predict prognosis in Bulgarian glioblastoma patients |
Q27851701 | IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma |
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Q24300323 | Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer |
Q24612429 | Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma |
Q38755638 | Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma. |
Q39458545 | Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production |
Q34069325 | Identification of isocitrate dehydrogenase 1 as a potential diagnostic and prognostic biomarker for non-small cell lung cancer by proteomic analysis. |
Q55462991 | Immunohistochemical analysis of 1844 human epithelial and haematopoietic tumours and sarcomas for IDH1R132H mutation. |
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Q47853442 | In vivo Metabolic Profiles as Determined by (31)P and short TE (1)H MR-Spectroscopy : No Difference Between Patients with IDH Wildtype and IDH Mutant Gliomas |
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Q37485784 | Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG. |
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Q33699608 | Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate |
Q36213070 | Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype |
Q36925070 | Isocitrate dehydrogenase 1 analysis differentiates gangliogliomas from infiltrative gliomas |
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Q38098586 | Isocitrate dehydrogenase 1: what it means to the neurosurgeon: a review |
Q36367409 | Isocitrate dehydrogenase mutations in gliomas |
Q34224704 | Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target |
Q37835774 | Isocitrate dehydrogenase mutations: a challenge to traditional views on the genesis and malignant progression of gliomas |
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