Effect of the hepatitis C virus protease inhibitor faldaprevir on the pharmacokinetics of an oral contraceptive containing ethinylestradiol and levonorgestrel in healthy female volunteers

scientific article

Effect of the hepatitis C virus protease inhibitor faldaprevir on the pharmacokinetics of an oral contraceptive containing ethinylestradiol and levonorgestrel in healthy female volunteers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.03589-14
P932PMC publication ID4291440
P698PubMed publication ID25385099

P2093author name stringJohn P Sabo
Mabrouk Elgadi
Fenglei Huang
Benjamin Lang
P2860cites workChronic hepatitis C: future treatmentQ26824075
HCV-related burden of disease in Europe: a systematic assessment of incidence, prevalence, morbidity, and mortalityQ27488220
Evolving epidemiology of hepatitis C virusQ29619973
The prevalence of hepatitis C virus infection in the United States, 1999 through 2002Q29619974
The effects of an oral contraceptive containing ethinyloestradiol and norgestrel on CYP3A activityQ35804348
Effect of an oral contraceptive preparation containing ethinylestradiol and gestodene on CYP3A4 activity as measured by midazolam 1'-hydroxylationQ36055339
Drug interactions between antiretrovirals and hormonal contraceptives.Q38083080
Preclinical Characterization of BI 201335, a C-Terminal Carboxylic Acid Inhibitor of the Hepatitis C Virus NS3-NS4A ProteaseQ39658512
P-glycoprotein (P-gp/MDR1)-mediated efflux of sex-steroid hormones and modulation of P-gp expression in vitroQ40529116
Mechanisms underlying benign and reversible unconjugated hyperbilirubinemia observed with faldaprevir administration in hepatitis C virus patients.Q42190800
Pharmacokinetic and pharmacodynamic interactions between the hepatitis C virus protease inhibitor, boceprevir, and the oral contraceptive ethinyl estradiol/norethindroneQ42208297
Hepatitis C infection and presence of advanced fibrosis: wait or treat? Why wait? There is no time to lose, is there?Q42987355
Faldaprevir combined with pegylated interferon alfa-2a and ribavirin in treatment-naïve patients with chronic genotype 1 HCV: SILEN-C1 trial.Q42988738
Faldaprevir combined with peginterferon alfa-2a and ribavirin in chronic hepatitis C virus genotype-1 patients with prior nonresponse: SILEN-C2 trial.Q42990229
Potency, safety, and pharmacokinetics of the NS3/4A protease inhibitor BI201335 in patients with chronic HCV genotype-1 infectionQ43031852
The pharmacokinetic interaction between an oral contraceptive containing ethinyl estradiol and norethindrone and the HCV protease inhibitor telaprevirQ43041878
Race but not age affects erythromycin breath test results in older hypertensive men.Q43554159
The involvement of CYP3A4 and CYP2C9 in the metabolism of 17 alpha-ethinylestradiolQ45013763
Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated Cooperstown 5+1 cocktailQ46807641
EASL Clinical Practice Guidelines: management of hepatitis C virus infectionQ86939378
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
levonorgestrelQ416950
Hepatitis C virusQ708693
P1104number of pages6
P304page(s)514-519
P577publication date2014-11-10
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleEffect of the hepatitis C virus protease inhibitor faldaprevir on the pharmacokinetics of an oral contraceptive containing ethinylestradiol and levonorgestrel in healthy female volunteers
P478volume59

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cites work (P2860)
Q40198351Effect of Steady-State Faldaprevir on Pharmacokinetics of Atorvastatin or Rosuvastatin in Healthy Volunteers: A Prospective Open-Label, Fixed-Sequence Crossover Study
Q49544121Role of CYP3A in Oral Contraceptives Clearance