review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1041572643 |
P356 | DOI | 10.1007/S12079-011-0130-6 |
P932 | PMC publication ID | 3088790 |
P698 | PubMed publication ID | 21516514 |
P5875 | ResearchGate publication ID | 51073539 |
P50 | author | Ann F. Chambers | Q37828718 |
P2093 | author name string | Alan B Tuck | |
Jennifer C Mutrie | |||
Pieter H Anborgh | |||
P2860 | cites work | The Hallmarks of Cancer | Q221226 |
Post-translationally modified residues of native human osteopontin are located in clusters: identification of 36 phosphorylation and five O-glycosylation sites and their biological implications | Q24534917 | ||
Osteopontin--a possible anchor of osteoclasts to bone | Q24558077 | ||
The cDNA and derived amino acid sequence for human osteopontin | Q24635888 | ||
Osteopontin | Q28140484 | ||
Tyrosine sulfation: an increasingly recognised post-translational modification of secreted proteins | Q28253942 | ||
Dephosphorylation of osteopontin and bone sialoprotein by osteoclastic tartrate-resistant acid phosphatase. Modulation of osteoclast adhesion in vitro | Q28254304 | ||
Osteopontin-c is a selective marker of breast cancer | Q28254727 | ||
cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN) | Q28258326 | ||
An osteopontin splice variant induces anchorage independence in human breast cancer cells | Q28281854 | ||
The role of Osteopontin in tumor metastasis | Q28289345 | ||
Osteopontin: role in cell signaling and cancer progression | Q28291041 | ||
The role of osteopontin in tumor progression and metastasis in breast cancer | Q28305027 | ||
Osteoclast migration on phosphorylated osteopontin is regulated by endogenous tartrate-resistant acid phosphatase | Q28570119 | ||
Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). | Q50335757 | ||
New dual monoclonal ELISA for measuring plasma osteopontin as a biomarker associated with survival in prostate cancer: clinical validation and comparison of multiple ELISAs. | Q51749238 | ||
A functional motif QLYxxYP is essential for osteopontin induced T lymphocyte activation and migration. | Q51770155 | ||
Comprehensive study on the prognostic role of osteopontin expression in oral squamous cell carcinoma. | Q51824699 | ||
Expression of osteopontin and CDX2: indications of phenotypes and prognosis in advanced gastric cancer. | Q51825298 | ||
An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma. | Q53334223 | ||
Proteomics discovery of metalloproteinase substrates in the cellular context by iTRAQ labeling reveals a diverse MMP-2 substrate degradome. | Q53579885 | ||
Matricellular proteins as modulators of wound healing and the foreign body response. | Q53701819 | ||
Identification of the Phosphorylated Sites of Metabolically32P-Labeled Osteopontin from Cultured Chicken Osteoblasts | Q58487930 | ||
Serial Plasma Osteopontin Levels Have Prognostic Value in Metastatic Breast Cancer | Q62496092 | ||
Osteopontin-induced, integrin-dependent migration of human mammary epithelial cells involves activation of the hepatocyte growth factor receptor (Met) | Q62496773 | ||
Osteopontin expression in a group of lymph node negative breast cancer patients | Q62497180 | ||
Osteopontin expression in lung cancer | Q62497417 | ||
Altered sialylation of osteopontin prevents its receptor-mediated binding on the surface of oncogenically transformed tsB77 cells | Q73343556 | ||
Osteopontin and p53 expression are associated with tumor progression in a case of synchronous, bilateral, invasive mammary carcinomas | Q73451082 | ||
Phosphorylation of osteopontin by Golgi apparatus casein kinase | Q73941062 | ||
Osteopontin expression in primary sarcomas of the pulmonary artery | Q77412582 | ||
Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival | Q77554252 | ||
Expression of osteopontin and vascular endothelial growth factor in benign and malignant bone tumors | Q78439155 | ||
Enhanced production of osteopontin in multiple myeloma: clinical and pathogenic implications | Q79129548 | ||
Osteopontin upregulation and polymerization by transglutaminase 2 in calcified arteries of Matrix Gla protein-deficient mice | Q79451630 | ||
Osteopontin in metastatic lesions as a prognostic marker in ovarian cancers | Q79548087 | ||
Asbestos exposure, pleural mesothelioma, and serum osteopontin levels | Q81344951 | ||
Expression of osteopontin and HGF/met in adult soft tissue tumors | Q81419450 | ||
The immunohistochemical expression profile of osteopontin in normal human tissues using two site-specific antibodies reveals a wide distribution of positive cells and extensive expression in the central and peripheral nervous systems | Q84590916 | ||
Tissue transglutaminase and its substrates in bone | Q28573074 | ||
The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin | Q28647119 | ||
Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by alpha9beta1 integrin | Q28647308 | ||
N-Glycan structures of an osteopontin from human bone | Q30840026 | ||
An integrated procedure of selective injection, sample stacking and fractionation of phosphopeptides for MALDI MS analysis | Q33280052 | ||
The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways | Q33540190 | ||
Elevated tumor and serum levels of the hypoxia-associated protein osteopontin are associated with prognosis for soft tissue sarcoma patients. | Q33551004 | ||
Reduction of elevated plasma osteopontin levels with resection of non-small-cell lung cancer | Q33710746 | ||
RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells | Q33713013 | ||
Plasma osteopontin: associations with survival and metastasis to bone in men with hormone-refractory prostate carcinoma. | Q33961207 | ||
Tumour-associated carbohydrate antigens in breast cancer | Q34048052 | ||
Osteopontin: a versatile regulator of inflammation and biomineralization | Q34096200 | ||
The functional and clinical roles of osteopontin in cancer and metastasis. | Q34119050 | ||
Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling | Q34121777 | ||
P700: the primary electron donor of photosystem I. | Q34424983 | ||
Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain | Q34442820 | ||
The metastasis gene osteopontin: a candidate target for cancer therapy | Q34515780 | ||
The role of osteopontin in breast cancer: clinical and experimental studies | Q34639848 | ||
Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435 | Q35046540 | ||
Functional heterogeneity of osteopontin isoforms in non-small cell lung cancer. | Q35065341 | ||
Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer | Q35221922 | ||
Role of osteopontin in tumour progression | Q35770935 | ||
Splice variants as cancer biomarkers | Q35826741 | ||
Osteopontin expression and distribution in human carcinomas. | Q35839272 | ||
Down-regulation of osteopontin attenuates breast tumour progression in vivo | Q35886642 | ||
Posttranslational modifications of bovine osteopontin: identification of twenty-eight phosphorylation and three O-glycosylation sites | Q36278922 | ||
Osteopontin expression in normal skin and non-melanoma skin tumors | Q36570295 | ||
Osteopontin overexpression in breast cancer: knowledge gained and possible implications for clinical management. | Q36920211 | ||
Control of osteopontin signaling and function by post-translational phosphorylation and protein folding | Q36957636 | ||
Osteopontin: regulation in tumor metastasis | Q37020157 | ||
Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applications | Q37316687 | ||
Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma | Q37421879 | ||
Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification | Q37441275 | ||
Role of the metastasis-promoting protein osteopontin in the tumour microenvironment | Q37769582 | ||
Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression | Q38327011 | ||
Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. | Q38354428 | ||
Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways | Q38357217 | ||
Elevated expression of secreted phosphoprotein I (osteopontin, 2ar) as a consequence of neoplastic transformation. | Q38728996 | ||
Overexpression of osteopontin in hepatocellular carcinoma and its relationships with metastasis, invasion of tumor cells | Q39614988 | ||
Down-regulation of osteopontin inhibits metastasis of hepatocellular carcinoma cells via a mechanism involving MMP-2 and uPA. | Q39617638 | ||
Expression pattern of osteopontin splice variants and its functions on cell apoptosis and invasion in glioma cells | Q39698825 | ||
A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells | Q39731482 | ||
Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines | Q39780008 | ||
Lung cancer osteopontin isoforms exhibit angiogenic functional heterogeneity. | Q39789110 | ||
Clinical significance of the upregulated osteopontin mRNA expression in human colorectal cancer | Q39798008 | ||
A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo | Q39810957 | ||
Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model | Q39852463 | ||
Tumorigenic properties of alternative osteopontin isoforms in mesothelioma | Q39872992 | ||
Multiple and specific mRNA processing targets for the major human hnRNP proteins | Q39958784 | ||
Osteopontin expression profiles predict pathological and clinical outcome in breast cancer. | Q40005261 | ||
The thrombin inhibitor Argatroban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms | Q40032019 | ||
Enhanced biological activity of polymeric osteopontin | Q40127298 | ||
Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties | Q40133189 | ||
Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells | Q40136588 | ||
Abrogation of the interaction between osteopontin and alphavbeta3 integrin reduces tumor growth of human lung cancer cells in mice. | Q40136876 | ||
Tissue transglutaminase expression promotes cell attachment, invasion and survival in breast cancer cells | Q40219915 | ||
Prognostic significance of osteopontin expression in human prostate cancer | Q40343105 | ||
Phosphorylated osteopontin promotes migration of human choriocarcinoma cells via a p70 S6 kinase-dependent pathway. | Q40461079 | ||
Prognostic significance of tissue transglutaminase in drug resistant and metastatic breast cancer | Q40483302 | ||
Nuclear factor-inducing kinase plays a crucial role in osteopontin-induced MAPK/IkappaBalpha kinase-dependent nuclear factor kappaB-mediated promatrix metalloproteinase-9 activation | Q40536966 | ||
Differential osteopontin expression in lung cancer | Q40784031 | ||
Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells | Q40937384 | ||
Cloning and characterization of the human osteopontin gene and its promoter | Q41437628 | ||
Recombinant GST-human osteopontin fusion protein is functional in RGD-dependent cell adhesion | Q41490633 | ||
Localization of transglutaminase-reactive glutamine residues in bovine osteopontin. | Q41770359 | ||
Osteopontin is a marker for cancer aggressiveness and patient survival | Q42393441 | ||
The carboxyl-terminal fragment of osteopontin suppresses arginine-glycine-asparatic acid-dependent cell adhesion | Q42820752 | ||
Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer. | Q44030350 | ||
A novel functional motif of osteopontin for human lymphocyte migration and survival | Q44759478 | ||
Osteopontin as a potential biomarker of proliferation and invasiveness for lung cancer | Q44832836 | ||
Bone sialoprotein II synthesized by cultured osteoblasts contains tyrosine sulfate | Q45227229 | ||
Osteopontin regulates multiple functions contributing to human colon cancer development and progression | Q45243201 | ||
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning | Q45728735 | ||
Immunohistochemical expression of osteopontin in gastric cancer | Q45760104 | ||
The clinical significance of serum markers of bone turnover in NSCLC patients: surveillance, management and prognostic implications. | Q46011523 | ||
Sulphation of secreted phosphoprotein I (SPPI, osteopontin) is associated with mineralized tissue formation | Q46274469 | ||
Comprehensive identification of post-translational modifications of rat bone osteopontin by mass spectrometry | Q46467646 | ||
Osteopontin, a substrate for transglutaminase and Factor XIII activity | Q46850555 | ||
Post-translational modification and proteolytic processing of urinary osteopontin | Q46855720 | ||
Expression of osteopontin in human glioma. Its correlation with the malignancy | Q48076092 | ||
Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies | Q48089758 | ||
Identification of potential serum biomarkers of glioblastoma: serum osteopontin levels correlate with poor prognosis | Q48173788 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 111-122 | |
P577 | publication date | 2011-04-26 | |
P1433 | published in | Journal of Cell Communication and Signaling | Q26841964 |
P1476 | title | Pre- and post-translational regulation of osteopontin in cancer | |
P478 | volume | 5 |
Q39863679 | A Randomized Phase II Trial of Short-Course Androgen Deprivation Therapy With or Without Bevacizumab for Patients With Recurrent Prostate Cancer After Definitive Local Therapy |
Q34785177 | Acute Myocardial Infarction and Pulmonary Diseases Result in Two Different Degradation Profiles of Elastin as Quantified by Two Novel ELISAs |
Q37673302 | Age-Related Loss in Bone Mineral Density of Rats Fed Lifelong on a Fish Oil-Based Diet Is Avoided by Coenzyme Q10 Addition. |
Q55499525 | Biomarkers for Pulmonary Vascular Remodeling in Systemic Sclerosis: A Pathophysiological Approach. |
Q37625382 | Bone sialoprotein and osteopontin in bone metastasis of osteotropic cancers |
Q39365743 | Both osteopontin-c and osteopontin-b splicing isoforms exert pro-tumorigenic roles in prostate cancer cells |
Q39426138 | C-terminal modification of osteopontin inhibits interaction with the αVβ3-integrin |
Q33823827 | Changes in the transcriptional profile in response to overexpression of the osteopontin-c splice isoform in ovarian (OvCar-3) and prostate (PC-3) cancer cell lines |
Q58114800 | Circulating Levels of Osteopontin Predict Patients' Outcome after Resection of Colorectal Liver Metastases |
Q64232823 | Correlation of OPN gene expression with proliferation and apoptosis of ovarian cancer cells and prognosis of patients |
Q35803772 | Diagnostic values of osteopontin combined with CA125 for ovarian cancer: a meta-analysis |
Q47554433 | Differential osteopontin expression in human osteoblasts derived from iliac crest and alveolar bone and its role in early stages of angiogenesis |
Q54345724 | Expression analysis of osteopontin mRNA splice variants in prostate cancer and benign prostatic hyperplasia. |
Q36164237 | FLJ10540 is associated with tumor progression in nasopharyngeal carcinomas and contributes to nasopharyngeal cell proliferation, and metastasis via osteopontin/CD44 pathway. |
Q37424578 | Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis. |
Q55443311 | Immobilized Osteopontin Enhances Adhesion but Suppresses Cytokine Release of Anti-IgE Activated Human Mast Cells. |
Q38712457 | Immune microenvironment of gliomas |
Q36578825 | Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization |
Q36091701 | Myocardial Expression Analysis of Osteopontin and Its Splice Variants in Patients Affected by End-Stage Idiopathic or Ischemic Dilated Cardiomyopathy. |
Q27026399 | New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases |
Q38009305 | Novel cardiac-specific biomarkers and the cardiovascular continuum |
Q26798763 | OPN -Revisited |
Q35837949 | Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways |
Q41590198 | Osteopontin (OPN) isoforms, diabetes, obesity, and cancer; what is one got to do with the other? A new role for OPN. |
Q36079101 | Osteopontin and thrombospondin-1 play opposite roles in promoting tumor aggressiveness of primary resected non-small cell lung cancer |
Q41099667 | Osteopontin at the Crossroads of Inflammation and Tumor Progression |
Q101237481 | Osteopontin binds ICOSL promoting tumor metastasis |
Q90446482 | Osteopontin expression and its relationship with prognostic factors in diffuse large B-cell lymphoma |
Q48263513 | Osteopontin expression in healing wounds of horses and in human keloids. |
Q47722577 | Osteopontin gene polymorphism association with milk traits and its expression analysis in milk of riverine buffalo. |
Q36002290 | Osteopontin in systemic sclerosis and its role in dermal fibrosis |
Q42063955 | Osteopontin induces growth of metastatic tumors in a preclinical model of non-small lung cancer |
Q36503987 | Osteopontin splice variants differentially exert clinicopathological features and biological functions in gastric cancer |
Q38832738 | Osteopontin splice variants expression is involved on docetaxel resistance in PC3 prostate cancer cells. |
Q37588399 | Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior |
Q33766277 | Osteopontin: A novel regulator at the cross roads of inflammation, obesity and diabetes |
Q39192350 | Osteopontin: its potential role in cancer of children and young adults |
Q37406721 | Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes |
Q44557093 | Phosphorylation of osteopontin in osteoarthritis degenerative cartilage and its effect on matrix metalloprotease 13. |
Q93024921 | Plasma High Mobility Group Box 1 (HMGB1), Osteopontin (OPN), and Hyaluronic Acid (HA) as Admissible Biomarkers for Endometriosis |
Q36184227 | Plasma osteopontin as a biomarker of prostate cancer aggression: relationship to risk category and treatment response. |
Q35677840 | Plasma osteopontin is a biomarker for the severity of alcoholic liver cirrhosis, not for hepatocellular carcinoma screening |
Q35593061 | Post-operative plasma osteopontin predicts distant metastasis in human colorectal cancer |
Q38198463 | Role of osteopontin in the pathophysiology of cancer |
Q39069785 | Serum Midkine and Osteopontin Levels as Diagnostic Biomarkers of Hepatocellular Carcinoma |
Q59126544 | Systematic analysis of genes involved in oral cancer metastasis to lymph nodes |
Q33999138 | TGFBR2 but not SPP1 genotype modulates osteopontin expression in Duchenne muscular dystrophy muscle |
Q36560184 | TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth and is associated with metastasis |
Q38354012 | Targeting osteopontin, the silent partner of Na+/H+ exchanger isoform 1 in cardiac remodeling |
Q39429761 | The Effect of Osteopontin on Microglia. |
Q92268244 | The non-synonymous mutation in bovine SPP1 gene influences carcass weight |
Q47733296 | Tumor expression of survivin, p53, cyclin D1, osteopontin and fibronectin in predicting the response to neo-adjuvant chemotherapy in children with advanced malignant peripheral nerve sheath tumor. |
Q28505746 | WFDC1 is a key modulator of inflammatory and wound repair responses |
Q55443217 | [Advances in Research of Osteopontion and Its Receptor CD44v in Tumor Invasion and Metastasis]. |
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