Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response

scientific article published on 24 November 2014

Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.02398-14
P932PMC publication ID4294228
P698PubMed publication ID25422270

P50authorEnmoore LinQ61278582
Louis SchofieldQ80331838
Danielle I StanisicQ86061713
Leanne J RobinsonQ88893986
Peter M SibaQ89223280
Benson KiniboroQ114307173
Sarah JavatiQ117223968
Peter A. ZimmermanQ39408524
Ingrid FelgerQ39408549
Freya FowkesQ42800053
James BeesonQ56780488
James W KazuraQ56781816
Ivo MuellerQ60043791
P2093author name stringChristopher L King
Jack S Richards
Melanie Koinari
P2860cites workCongenital malariaQ75685132
Establishing the extent of malaria transmission and challenges facing pre-elimination in the Republic of DjiboutiQ24810344
Serological markers suggest heterogeneity of effectiveness of malaria control interventions on Bioko Island, equatorial GuineaQ28744515
Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malariaQ31169310
Acquisition of growth-inhibitory antibodies against blood-stage Plasmodium falciparumQ33380204
Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adultsQ33380213
Rapid assessment of malaria transmission using age-specific sero-conversion ratesQ33475618
The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malariaQ33512926
The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and meta-analysisQ33526349
Differential patterns of infection and disease with P. falciparum and P. vivax in young Papua New Guinean childrenQ33530114
Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodiesQ33548663
Estimating medium- and long-term trends in malaria transmission by using serological markers of malaria exposureQ33935818
Specificity of the protective antibody response to apical membrane antigen 1Q34007362
Purification, characterization, and immunogenicity of the refolded ectodomain of the Plasmodium falciparum apical membrane antigen 1 expressed in Escherichia coliQ34122492
Target antigen, age, and duration of antigen exposure independently regulate immunoglobulin G subclass switching in malariaQ34301187
Spatial and temporal variation in abundance of Anopheles (Diptera:Culicidae) in a malaria endemic area in Papua New GuineaQ34421706
Research priorities for the development and implementation of serological tools for malaria surveillanceQ34500035
The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibodyQ34601904
Factors associated with immunoglobulin G subclass polarization in naturally acquired antibodies to Plasmodium falciparum merozoite surface proteins: a cross-sectional survey in Brazilian AmazoniaQ34720387
Development of a multiplex PCR-ligase detection reaction assay for diagnosis of infection by the four parasite species causing malaria in humansQ34781485
Antibodies to polymorphic invasion-inhibitory and non-Inhibitory epitopes of Plasmodium falciparum apical membrane antigen 1 in human malariaQ34827195
Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young childrenQ35016669
Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemicQ35016677
Serum antibodies from malaria-exposed people recognize conserved epitopes formed by the two epidermal growth factor motifs of MSP1(19), the carboxy-terminal fragment of the major merozoite surface protein of Plasmodium falciparumQ35383761
Natural immune response to the C-terminal 19-kilodalton domain of Plasmodium falciparum merozoite surface protein 1.Q35505807
Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malariaQ35569042
Force of infection is key to understanding the epidemiology of Plasmodium falciparum malaria in Papua New Guinean childrenQ36056571
Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodiesQ36227228
New insights into acquisition, boosting, and longevity of immunity to malaria in pregnant womenQ36330969
Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy?Q36391845
Clinical immunity to malariaQ36412877
Humoral responses to plasmodium falciparum blood-stage antigens and association with incidence of clinical malaria in children living in an area of seasonal malaria transmission in Burkina Faso, West Africa.Q36421572
Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malariaQ36594057
Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker developmentQ36984161
The risk of malarial infections and disease in Papua New Guinean children.Q37088901
Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illnessQ37099503
A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malariaQ37148056
Erythrocyte-binding antigens of Plasmodium falciparum are targets of human inhibitory antibodies and function to evade naturally acquired immunityQ37202344
Recent insights into humoral and cellular immune responses against malariaQ37291684
Comparison of Plasmodium falciparum allelic frequency distribution in different endemic settings by high-resolution genotypingQ37415484
The future for blood-stage vaccines against malariaQ37471465
Factors determining the heterogeneity of malaria incidence in children in Kampala, UgandaQ38876186
Comparison of PCR-RFLP and Genescan-based genotyping for analyzing infection dynamics of Plasmodium falciparum.Q38998328
Spatial variation of malaria incidence in young children from a geographically homogeneous area with high endemicityQ39148311
Serum IgG3 to the Plasmodium falciparum merozoite surface protein 2 is strongly associated with a reduced prospective risk of malariaQ39247931
High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal KenyaQ39362550
Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria.Q39417737
Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparumQ39518517
Human antibody response to Plasmodium falciparum merozoite surface protein 2 is serogroup specific and predominantly of the immunoglobulin G3 subclassQ39823427
Enhanced Plasmodium falciparum merozoite phagocytosis by monocytes from immune individualsQ40613128
Adjusting for heterogeneity of malaria transmission in longitudinal studiesQ42577113
Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytesQ42938913
Antibodies against Plasmodium falciparum vaccine candidates in infants in an area of intense and perennial transmission: relationships with clinical malaria and with entomological inoculation ratesQ43952320
Small-area variations in the epidemiology of malaria in Madang Province.Q44808119
Clinical immunity to Plasmodium falciparum malaria is associated with serum antibodies to the 19-kDa C-terminal fragment of the merozoite surface antigen, PfMSP-1.Q46334562
Action of Malarial Antibody in vitroQ47680023
IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP2): increasing prevalence with age and association with clinical immunity to malaria.Q47830190
Human antibodies to the 19kDa C-terminal fragment of Plasmodium falciparum merozoite surface protein 1 inhibit parasite growth in vitroQ47845842
Association of the IgG response to Plasmodium falciparum merozoite protein (C-terminal 19 kD) with clinical immunity to malaria in the Brazilian Amazon regionQ47911253
Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemiaQ47954510
Evidence that the erythrocyte invasion ligand PfRh2 is a target of protective immunity against Plasmodium falciparum malariaQ47957417
Gamma-globulin and acquired immunity to human malariaQ47957467
Antibodies to the conserved C-terminal domain of the Plasmodium falciparum merozoite surface protein 1 and to the merozoite extract and their relationship with in vitro inhibitory antibodies and protection against clinical malaria in a Senegalese viQ48000659
Correlation of high levels of antibodies to multiple pre-erythrocytic Plasmodium falciparum antigens and protection from infection.Q48012112
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
antibodyQ79460
Plasmodium falciparumQ311383
merozoiteQ2296434
P304page(s)646-660
P577publication date2014-11-24
P1433published inInfection and ImmunityQ6029193
P1476titleAcquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response
P478volume83

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