The GrlR-GrlA regulatory system coordinately controls the expression of flagellar and LEE-encoded type III protein secretion systems in enterohemorrhagic Escherichia coli

scientific article

The GrlR-GrlA regulatory system coordinately controls the expression of flagellar and LEE-encoded type III protein secretion systems in enterohemorrhagic Escherichia coli is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JB.00352-06
P932PMC publication ID1540053
P698PubMed publication ID16885436

P2093author name stringYan Lu
Sunao Iyoda
Makoto Ohnishi
Haruo Watanabe
Nobuo Koizumi
Takehito Saitoh
Hitomi Satou
P2860cites workDiarrheagenic Escherichia coliQ24533466
Bacteria-host communication: the language of hormonesQ24678649
The bvgAS locus negatively controls motility and synthesis of flagella in Bordetella bronchisepticaQ24684499
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
Global gene regulation in Yersinia enterocolitica: effect of FliA on the expression levels of flagellar and plasmid-encoded virulence genesQ28487780
Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmidQ29614535
An activator of glutamate decarboxylase genes regulates the expression of enteropathogenic Escherichia coli virulence genes through control of the plasmid-encoded regulator, Per.Q30716869
Positive effects of multiple pch genes on expression of the locus of enterocyte effacement genes and adherence of enterohaemorrhagic Escherichia coli O157 : H7 to HEp-2 cellsQ31095273
The LEE1 promoters from both enteropathogenic and enterohemorrhagic Escherichia coli can be activated by PerC-like proteins from either organismQ33699768
A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cellsQ33834748
ClpXP protease controls expression of the type III protein secretion system through regulation of RpoS and GrlR levels in enterohemorrhagic Escherichia coliQ33855509
Multiple control of flagellum biosynthesis in Escherichia coli: role of H-NS protein and the cyclic AMP-catabolite activator protein complex in transcription of the flhDC master operonQ33993289
The flagellar sigma factor FliA (sigma(28)) regulates the expression of Salmonella genes associated with the centisome 63 type III secretion systemQ34004319
The locus of enterocyte effacement (LEE)-encoded regulator controls expression of both LEE- and non-LEE-encoded virulence factors in enteropathogenic and enterohemorrhagic Escherichia coli.Q34004916
Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formationQ34022530
Integration host factor (IHF) mediates repression of flagella in enteropathogenic and enterohaemorrhagic Escherichia coliQ44837517
Ectopic expression of the flagellar regulon alters development of the Bordetella-host interactionQ46490294
Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8.Q46809881
Structure and transcriptional control of the flagellar master operon of Salmonella typhimuriumQ47903865
Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cellsQ48042079
Promoter analysis of the class 2 flagellar operons of SalmonellaQ50122591
Molecular dissection of the flagellum-specific anti-sigma factor, FlgM, of Salmonella typhimuriumQ50141336
Functional homology of fla genes between Salmonella typhimurium and Escherichia coliQ50219373
Gene fliA encodes an alternative sigma factor specific for flagellar operons in Salmonella typhimurium.Q50465502
Identification of a negative regulator for the pathogenicity island of enterohemorrhagic Escherichia coli O157:H7.Q52561663
Dual regulatory pathways integrating the RcsC-RcsD-RcsB signalling system control enterohaemorrhagic Escherichia coli pathogenicity.Q53657202
ClpXP controls the expression of LEE genes in enterohaemorrhagic Escherichia coli.Q54477630
Yeast two-hybrid system survey of interactions between LEE-encoded proteins of enteropathogenic Escherichia coli.Q54520438
RcsCDB His-Asp phosphorelay system negatively regulates the flhDC operon in Escherichia coli.Q54521795
Thermoregulated expression of virulence genes in enteropathogenic Escherichia coli.Q54538763
The flagella of enteropathogenic Escherichia coli mediate adherence to epithelial cells.Q54546798
A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12.Q54574143
Role of the nucleoid-associated protein Fis in the regulation of virulence properties of enteropathogenic Escherichia coliQ58827834
Enteropathogenic and enterohaemorrhagic Escherichia coli : more subversive elementsQ59307481
Co-ordination of pathogenicity island expression by the BipA GTPase in enteropathogenic Escherichia coli (EPEC)Q73215720
Hierarchy in the expression of the locus of enterocyte effacement genes of enteropathogenic Escherichia coliQ73265517
Up-regulation of the Yersinia enterocolitica yop regulon by deletion of the flagellum master operon flhDC.Q34312629
A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogensQ34642972
Transcriptional regulation of flhDC by QseBC and sigma (FliA) in enterohaemorrhagic Escherichia coliQ34650933
Supramolecular structure of the Salmonella typhimurium type III protein secretion systemQ34746894
Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cellsQ34853145
Increased adherence to Caco-2 cells caused by disruption of the yhiE and yhiF genes in enterohemorrhagic Escherichia coli O157:H7Q34934490
RtsA and RtsB coordinately regulate expression of the invasion and flagellar genes in Salmonella enterica serovar Typhimurium.Q35662912
The H-NS protein is involved in the biogenesis of flagella in Escherichia coliQ35974947
Flagellar transcriptional activators FlbB and FlaI: gene sequences and 5' consensus sequences of operons under FlbB and FlaI controlQ36199169
Transcriptional control of flagellar genes in Escherichia coli K-12Q36262495
Characterization of Escherichia coli flagellar mutants that are insensitive to catabolite repressionQ36761300
Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coliQ36783792
Identification of a novel Escherichia coli gene whose expression is dependent on the flagellum-specific sigma factor, FliA, but dispensable for motility developmentQ36889514
The eae gene of enteropathogenic Escherichia coli encodes a 94-kilodalton membrane protein, the expression of which is influenced by the EAF plasmidQ36989598
Dissecting virulence: systematic and functional analyses of a pathogenicity islandQ37074383
Role of hha and ler in transcriptional regulation of the esp operon of enterohemorrhagic Escherichia coli O157:H7Q37583319
Positive regulation of motility and flhDC expression by the RNA-binding protein CsrA of Escherichia coliQ38302059
FlhD/FlhC-regulated promoters analyzed by gene array and lacZ gene fusionsQ38302275
LrhA as a new transcriptional key regulator of flagella, motility and chemotaxis genes in Escherichia coli.Q38364145
Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar typhimuriumQ39538569
Quorum-sensing Escherichia coli regulator A: a regulator of the LysR family involved in the regulation of the locus of enterocyte effacement pathogenicity island in enterohemorrhagic E. coli.Q39655068
The ClpXP ATP-dependent protease regulates flagellum synthesis in Salmonella enterica serovar typhimurium.Q39694510
Modulation of flagellar expression in Escherichia coli by acetyl phosphate and the osmoregulator OmpR.Q39837971
A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA.Q39891943
The FlhD/FlhC complex, a transcriptional activator of the Escherichia coli flagellar class II operonsQ39899278
Role of the FliA-FlgM regulatory system on the transcriptional control of the flagellar regulon and flagellar formation in Salmonella typhimuriumQ39932319
Transcriptional analysis of the flagellar regulon of Salmonella typhimuriumQ39943833
Mouse intestine selects nonmotile flhDC mutants of Escherichia coli MG1655 with increased colonizing ability and better utilization of carbon sourcesQ40381453
Regulators encoded in the Escherichia coli type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic E. coli O157:H7.Q40422063
Actin accumulation at sites of bacterial adhesion to tissue culture cells: basis of a new diagnostic test for enteropathogenic and enterohemorrhagic Escherichia coliQ40426825
A flagellar gene fliZ regulates the expression of invasion genes and virulence phenotype in Salmonella enterica serovar TyphimuriumQ40609349
Genetic and molecular analyses of the interaction between the flagellum-specific sigma and anti-sigma factors in Salmonella typhimuriumQ40793356
Roles for motility in bacterial–host interactionsQ41528040
The Per regulon of enteropathogenic Escherichia coli : identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)-encoded regulator (Ler).Q42605904
Transcriptional regulation of type III secretion genes in enteropathogenic Escherichia coli: Ler antagonizes H-NS-dependent repressionQ42641819
Isolation and characterization of Escherichia coli hag operator mutants whose hag48 expression has become repressible by a Salmonella H1 repressorQ42644600
Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli.Q42673580
The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69.Q42677853
Structure and expression of the fliA operon of Salmonella typhimuriumQ43169522
Promoter-detection vectors for Escherichia coli with multiple useful featuresQ43591254
Proteomic discovery of cellular substrates of the ClpXP protease reveals five classes of ClpX-recognition signalsQ44384522
Turnover of FlhD and FlhC, master regulator proteins for Salmonella flagellum biogenesis, by the ATP-dependent ClpXP proteaseQ44390470
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)5682-5692
P577publication date2006-08-01
P1433published inJournal of BacteriologyQ478419
P1476titleThe GrlR-GrlA regulatory system coordinately controls the expression of flagellar and LEE-encoded type III protein secretion systems in enterohemorrhagic Escherichia coli
P478volume188

Reverse relations

cites work (P2860)
Q37629621A long-term epigenetic memory switch controls bacterial virulence bimodality
Q42706675Activation of motility by sensing short-chain fatty acids via two steps in a flagellar gene regulatory cascade in enterohemorrhagic Escherichia coli
Q56344646After the fact(or): post-transcriptional gene regulation in enterohemorrhagic O157:H7
Q61810394Characterization of the Mode of Action of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis
Q42561295Characterization of the effects of salicylidene acylhydrazide compounds on type III secretion in Escherichia coli O157:H7.
Q30580108Comparison of strand-specific transcriptomes of enterohemorrhagic Escherichia coli O157:H7 EDL933 (EHEC) under eleven different environmental conditions including radish sprouts and cattle feces
Q64926484Control freaks-signals and cues governing the regulation of virulence in attaching and effacing pathogens.
Q35671686Coordinate control of the locus of enterocyte effacement and enterohemolysin genes by multiple common virulence regulators in enterohemorrhagic Escherichia coli
Q40169819Cross talk between type III secretion and flagellar assembly systems in Pseudomonas aeruginosa.
Q37499756Determining the relative contribution and hierarchy of hha and qseBC in the regulation of flagellar motility of Escherichia coli O157:H7.
Q33931539Differences in adherence and virulence gene expression between two outbreak strains of enterohaemorrhagic Escherichia coli O157 : H7.
Q42592138Engineering the Controlled Assembly of Filamentous Injectisomes in E. coli K-12 for Protein Translocation into Mammalian Cells
Q34177961Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements
Q34586498EspO1-2 regulates EspM2-mediated RhoA activity to stabilize formation of focal adhesions in enterohemorrhagic Escherichia coli-infected host cells
Q36018614Expression Regulation of Polycistronic lee3 Genes of Enterohaemorrhagic Escherichia coli
Q27005178From ingestion to colonization: the influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coli
Q39235366Functional Characterization of EscK (Orf4), a Sorting Platform Component of the Enteropathogenic Escherichia coli Injectisome
Q42233920Global Regulator of Virulence A (GrvA) Coordinates Expression of Discrete Pathogenic Mechanisms in Enterohemorrhagic Escherichia coli through Interactions with GadW-GadE.
Q42601067Hfq affects the expression of the LEE pathogenicity island in enterohaemorrhagic Escherichia coli
Q38351169Hfq negatively regulates type III secretion in EHEC and several other pathogens
Q34927627Honing the message: post-transcriptional and post-translational control in attaching and effacing pathogens
Q35566897Host attachment and fluid shear are integrated into a mechanical signal regulating virulence in Escherichia coli O157:H7.
Q34082078Identification of a novel prophage regulator in Escherichia coli controlling the expression of type III secretion.
Q38676435Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds.
Q53489640IgA and IgG antibody responses following systemic immunization of cattle with native H7 flagellin differ in epitope recognition and capacity to neutralise TLR5 signalling.
Q30278051Interkingdom Chemical Signaling in Enterohemorrhagic Escherichia coli O157:H7.
Q28833589Mechanosensing regulates virulence in Escherichia coli O157:H7
Q41814304Molecular characterization of GrlA, a specific positive regulator of ler expression in enteropathogenic Escherichia coli.
Q54372522Organization of the LEE1 operon regulatory region of enterohaemorrhagic Escherichia coli O157:H7 and activation by GrlA.
Q45944240PerC and GrlA independently regulate Ler expression in enteropathogenic Escherichia coli.
Q41788447QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli
Q42188303QseA directly activates transcription of LEE1 in enterohemorrhagic Escherichia coli
Q27644824Structure of GrlR and the Implication of Its EDED Motif in Mediating the Regulation of Type III Secretion System in EHEC
Q27686888Structure of GrlR-GrlA complex that prevents GrlA activation of virulence genes
Q35568020The gut bacterium Bacteroides thetaiotaomicron influences the virulence potential of the enterohemorrhagic Escherichia coli O103:H25
Q34598830The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7
Q41768353The tib adherence locus of enterotoxigenic Escherichia coli is regulated by cyclic AMP receptor protein.
Q36747838Transcription of the ehx enterohemolysin gene is positively regulated by GrlA, a global regulator encoded within the locus of enterocyte effacement in enterohemorrhagic Escherichia coli
Q38586932Type III secretion systems: the bacterial flagellum and the injectisome
Q30418883Vibrio parahaemolyticus ExsE is requisite for initial adhesion and subsequent type III secretion system 1-dependent autophagy in HeLa cells
Q43096103σ(N) -dependent control of acid resistance and the locus of enterocyte effacement in enterohemorrhagic Escherichia coli is activated by acetyl phosphate in a manner requiring flagellar regulator FlhDC and the σ(S) antagonist FliZ.

Search more.