scholarly article | Q13442814 |
P356 | DOI | 10.1056/NEJMOA0810787 |
P698 | PubMed publication ID | 19494217 |
P50 | author | Helen J Lachmann | Q56426736 |
Éric Hachulla | Q57413861 | ||
Pierre Quartier | Q37838790 | ||
P2093 | author name string | Philip N Hawkins | |
Albert Widmer | |||
Canakinumab in CAPS Study Group | |||
Isabelle Kone-Paut | |||
Jasmin B Kuemmerle-Deschner | |||
Kieron S Leslie | |||
Neha Patel | |||
Xavier Gitton | |||
P433 | issue | 23 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cryopyrin-associated periodic syndrome | Q1771331 |
P304 | page(s) | 2416-2425 | |
P577 | publication date | 2009-06-01 | |
P1433 | published in | The New England Journal of Medicine | Q582728 |
P1476 | title | Use of canakinumab in the cryopyrin-associated periodic syndrome | |
P478 | volume | 360 |
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Q38805718 | A Comprehensive Overview of the Hereditary Periodic Fever Syndromes |
Q99240141 | A Review on Current Repurposing Drugs for the Treatment of COVID-19: Reality and Challenges |
Q33622218 | A case of cryopyrin-associated periodic syndrome with kidney transplant failure |
Q90289994 | A case report of locally invasive Aspergillus fumigatus infection in a patient on canakinumab |
Q37869439 | A clinical perspective of IL-1β as the gatekeeper of inflammation |
Q34632661 | A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features. |
Q27687429 | A preliminary score for the assessment of disease activity in hereditary recurrent fevers: results from the AIDAI (Auto-Inflammatory Diseases Activity Index) Consensus Conference. |
Q38633441 | A safety evaluation of canakinumab for the treatment of systemic onset juvenile idiopathic arthritis |
Q38773387 | A systematic approach to autoinflammatory syndromes: a spelling booklet for the beginner |
Q84100413 | Accelerate medical breakthroughs by ending disease earmarks |
Q84801790 | Acute inflammatory arthritis: interleukin-1 blockade: a magic wand for gout? |
Q39016299 | An Update on the Use of Immunomodulators in Primary Immunodeficiencies |
Q34254955 | An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome |
Q35219001 | An expanding role for interleukin-1 blockade from gout to cancer |
Q64110826 | An innate interaction between IL-18 and the propeptide that inactivates its precursor form |
Q59136398 | Anakinra Therapy for Non-cancer Inflammatory Diseases |
Q38993312 | Anakinra and related drugs targeting interleukin-1 in the treatment of cryopyrin-associated periodic syndromes |
Q37277309 | Anakinra as a diagnostic challenge and treatment option for systemic autoinflammatory disorders of undefined etiology |
Q38168948 | Anakinra for cryopyrin-associated periodic syndrome |
Q40852651 | Analysis of clinical trials with biologics using dose-time-response models |
Q27495968 | Anti-Interleukin-1 Agents in Adult Onset Still's Disease |
Q37118156 | Anti-inflammatory Agents: Present and Future |
Q55293840 | Anti-inflammatory cytokine and angiogenic factors levels in vitreous samples of diabetic retinopathy patients. |
Q51722492 | Applying physiological and biochemical concepts to optimize biological drug development. |
Q38085854 | Autoinflammation: From monogenic syndromes to common skin diseases |
Q34369278 | Autoinflammation: the prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses |
Q35558406 | Autoinflammation: translating mechanism to therapy |
Q37048084 | Autoinflammatory Skin Disorders: The Inflammasomme in Focus |
Q38715104 | Autoinflammatory Syndromes in Children |
Q36520994 | Autoinflammatory disease reloaded: a clinical perspective |
Q40376307 | Autoinflammatory diseases in childhood |
Q40153519 | Autoinflammatory syndromes as causes of fever of unknown origin |
Q40326095 | Autoinflammatory syndromes/fever syndromes |
Q37784856 | Autoinflammatory syndromes: diagnosis and management |
Q34135558 | Averting inflammation by targeting the cytokine environment |
Q27011650 | Beyond the NLRP3 inflammasome: autoinflammatory diseases reach adolescence |
Q38060204 | Bioanalysis of target biomarker and PK/PD relevancy during the development of biotherapeutics |
Q37887422 | Biologic modulators in allergic and autoinflammatory diseases |
Q37077564 | Biological treatments: new weapons in the management of monogenic autoinflammatory disorders |
Q39084627 | Biologics for Targeting Inflammatory Cytokines, Clinical Uses, and Limitations. |
Q37765830 | Biologics in children's autoimmune disorders: efficacy and safety |
Q37696271 | Blockade of interleukin 1 in type 1 diabetes mellitus |
Q34822708 | Blocking interleukin-1 in rheumatic diseases |
Q37821071 | Blocking interleukin-1β in acute and chronic autoinflammatory diseases |
Q48088115 | Bone involvement in monogenic autoinflammatory syndromes |
Q36702456 | Bridging Clinical Outcomes of Canakinumab Treatment in Patients With Rheumatoid Arthritis With a Population Model of IL-1β Kinetics |
Q54237287 | CANTOS: A breakthrough that proves the inflammatory hypothesis of atherosclerosis. |
Q38473823 | CAPS--pathogenesis, presentation and treatment of an autoinflammatory disease |
Q24642193 | Canakinumab |
Q35620372 | Canakinumab (ACZ885, a fully human IgG1 anti-IL-1β mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS) |
Q35535362 | Canakinumab as rescue therapy in familial Mediterranean fever refractory to conventional treatment |
Q54806476 | Canakinumab for the cryopyrin-associated periodic syndromes |
Q38814103 | Canakinumab for the treatment of TNF-receptor associated periodic syndrome |
Q40199493 | Canakinumab for the treatment of children with colchicine-resistant familial Mediterranean fever: a 6-month open-label, single-arm pilot study |
Q38865019 | Canakinumab for the treatment of familial Mediterranean fever. |
Q38255582 | Canakinumab for the treatment of systemic juvenile idiopathic arthritis |
Q37800938 | Canakinumab for treatment of cryopyrin-associated periodic syndrome |
Q40427207 | Canakinumab in adults with steroid-refractory pyoderma gangrenosum. |
Q37331996 | Canakinumab in patients with cryopyrin-associated periodic syndrome: an update for clinicians |
Q38085662 | Canakinumab in pediatric rheumatic diseases |
Q35012174 | Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study |
Q35092969 | Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat Gouty Arthritis by suppressing inflammation: results of a randomized, dose-ranging study |
Q98648527 | Canakinumab to reduce deterioration of cardiac and respiratory function in SARS-CoV-2 associated myocardial injury with heightened inflammation (canakinumab in Covid-19 cardiac injury: The three C study) |
Q37604504 | Canakinumab treatment for patients with active recurrent or chronic TNF receptor-associated periodic syndrome (TRAPS): an open-label, phase II study |
Q54806474 | Canakinumab: a human anti-IL-1β monoclonal antibody for the treatment of cryopyrin-associated periodic syndromes |
Q37968285 | Canakinumab: in patients with cryopyrin-associated periodic syndromes |
Q34336335 | Caspase functions in cell death and disease |
Q89526718 | Caspases in Cell Death, Inflammation, and Gasdermin-Induced Pyroptosis |
Q92665944 | Cell death-mediated cytokine release and its therapeutic implications |
Q40231494 | Challenges in diagnosing Muckle-Wells syndrome: identifying two distinct phenotypes |
Q28066948 | Chronic Infantile Neurological Cutaneous and Articular (CINCA) syndrome: a review |
Q35928265 | Chronic inflammation in cancer development. |
Q37942581 | Clinical and biochemical landmarks in systemic autoinflammatory diseases |
Q40049062 | Clinical and molecular phenotypes of low-penetrance variants in NLRP3: Diagnostic and therapeutic challenges |
Q42075063 | Clinical and transcriptional response to the long-acting interleukin-1 blocker canakinumab in Blau syndrome-related uveitis |
Q36903004 | Clinical characteristics in subjects with NLRP3 V198M diagnosed at a single UK center and a review of the literature |
Q37026106 | Closing the loop on inflammation and atherothrombosis: why perform the CIRT and CANTOS trials? |
Q37986236 | Cold-induced urticaria with a familial transmission: a case report and review of the literature |
Q35886682 | Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain |
Q50051013 | Confounding role of tumor necrosis factor in cryopyrin-associated periodic syndromes. |
Q89746290 | Consensus protocols for the diagnosis and management of the hereditary autoinflammatory syndromes CAPS, TRAPS and MKD/HIDS: a German PRO-KIND initiative |
Q33673719 | Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta |
Q38845570 | Cooling down inflammation in type 2 diabetes: how strong is the evidence for cardiometabolic benefit? |
Q43701983 | Corneal response to canakinumab in cryopyrin associated periodic fever syndrome |
Q40356964 | Critical appraisal of canakinumab in the treatment of adults and children with cryopyrin-associated periodic syndrome (CAPS). |
Q36137849 | Critical role for mast cells in interleukin-1β-driven skin inflammation associated with an activating mutation in the nlrp3 protein |
Q40289375 | Cryopyrin-associated periodic syndrome |
Q51533520 | Cryopyrin-associated periodic syndrome: an autoinflammatory disease manifested as neutrophilic urticarial dermatosis with additional perieccrine involvement |
Q37811988 | Cryopyrin-associated periodic syndrome: an update on diagnosis and treatment response |
Q37688957 | Cryopyrin-associated periodic syndromes: background and therapeutics |
Q37984096 | Cryopyrin-associated periodic syndromes: diagnosis and management |
Q97521410 | Current Therapeutic Options for the Main Monogenic Autoinflammatory Diseases and PFAPA Syndrome: Evidence-Based Approach and Proposal of a Practical Guide |
Q27693189 | Current concepts and future directions in the pathogenesis and treatment of non-infectious intraocular inflammation |
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Q37871438 | Current status of understanding the pathogenesis and management of patients with NOMID/CINCA. |
Q38574807 | Current treatment recommendations and considerations for cryopyrin-associated periodic syndrome |
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Q37875779 | Danger signals activating innate immunity in graft-versus-host disease |
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Q40210237 | Diagnostic validity of colchicine in patients with Familial Mediterranean fever |
Q37919837 | Does this patient have periodic fever syndrome? |
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Q36798016 | Efficacy of anti-IL-1 treatment in familial Mediterranean fever: a systematic review of the literature |
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Q28082757 | Evasion of inflammasome activation by microbial pathogens |
Q40179129 | Evidence of treatment of chronic inflammation in childhood and adolescence with biologics |
Q37800842 | Fevers and the Rheumatologist |
Q26770209 | From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection |
Q38528624 | From bench to bedside and back again: translational research in autoinflammation |
Q37077793 | From the Mediterranean to the sea of Japan: the transcontinental odyssey of autoinflammatory diseases |
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Q39243858 | Juvenile idiopathic arthritis: management and therapeutic options |
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Q56962731 | Kälteinduzierte Quaddeln und Angioödeme |
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Q57273753 | Lifelong urticaria and multiple unexplained systemic symptoms |
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