Mechanisms of transforming growth factor-beta receptor endocytosis and intracellular sorting differ between fibroblasts and epithelial cells

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Mechanisms of transforming growth factor-beta receptor endocytosis and intracellular sorting differ between fibroblasts and epithelial cells is …
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scholarly articleQ13442814

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P356DOI10.1091/MBC.12.3.675
P932PMC publication ID30972
P698PubMed publication ID11251079
P5875ResearchGate publication ID12081559

P2093author name stringD Yao
E B Leof
J J Doré
M Edens
N Garamszegi
E L Sholl
P2860cites workTGF-beta signal transductionQ22003891
Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexesQ24336247
TGF beta signals through a heteromeric protein kinase receptor complexQ24337608
TGF-beta signalling from cell membrane to nucleus through SMAD proteinsQ28131770
Mechanism of activation of the TGF-beta receptorQ28245861
Interaction of tyrosine-based sorting signals with clathrin-associated proteinsQ28290076
Phosphorylation of Ser165 in TGF-beta type I receptor modulates TGF-beta1-induced cellular responsesQ28631366
Endocytosis and molecular sortingQ29616706
Clathrin-coated vesicle formation and protein sorting: an integrated processQ29619729
Signal-dependent membrane protein trafficking in the endocytic pathwayQ29622948
Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimersQ33888963
Heteromeric and homomeric transforming growth factor-beta receptors show distinct signaling and endocytic responses in epithelial cellsQ34480656
Signaling by chimeric erythropoietin-TGF-beta receptors: homodimerization of the cytoplasmic domain of the type I TGF-beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction.Q35907449
The tyrosine-based lysosomal targeting signal in lamp-1 mediates sorting into Golgi-derived clathrin-coated vesiclesQ35909761
Distribution and modulation of the cellular receptor for transforming growth factor-betaQ36217344
The types II and III transforming growth factor-beta receptors form homo-oligomersQ36234419
Recruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinaseQ36235312
Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable componentsQ36237576
Oligomeric structure of type I and type II transforming growth factor beta receptors: homodimers form in the ER and persist at the plasma membraneQ36276659
Insulin receptor kinase activation releases a constraint maintaining the receptor on microvilliQ36719682
Distinct endocytic responses of heteromeric and homomeric transforming growth factor beta receptorsQ36942050
GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complexQ37697197
Clathrin, adaptors, and sortingQ37902930
Homomeric interactions between type II transforming growth factor-beta receptors.Q38304473
Identification of important regions in the cytoplasmic juxtamembrane domain of type I receptor that separate signaling pathways of transforming growth factor-betaQ38361883
Sendai virus assembly: M protein binds to viral glycoproteins in transit through the secretory pathway.Q40043814
Membrane dynamics in endocytosis.Q40939375
Effect of brefeldin A and lysosomotropic reagents on intracellular trafficking of epidermal growth factor and transferrin in Madin-Darby canine kidney epithelial cellsQ40998325
TGFbeta signaling: receptors, transducers, and Mad proteins.Q41010880
Chimeric granulocyte/macrophage colony-stimulating factor/transforming growth factor-beta (TGF-beta) receptors define a model system for investigating the role of homomeric and heteromeric receptors in TGF-beta signalingQ41168784
Regulation of differentiation by TGF-betaQ41239396
The GS domain of the transforming growth factor-beta type I receptor is important in signal transductionQ41369260
Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions.Q41461795
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptorsQ41527421
Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.Q41717780
Internalization of transforming growth factor-beta and its receptor in BALB/c 3T3 fibroblastsQ41915194
Binding and internalization of transforming growth factor-beta 1 by human hepatoma cells: evidence for receptor recyclingQ41941810
Rapid constitutive internalization and externalization of epidermal growth factor receptors in isolated rat hepatocytes. Monensin inhibits receptor externalization and reduces the capacity for continued endocytosis of epidermal growth factorQ41947153
Secretion of the baby hamster kidney 30-kDa galactose-binding lectin from polarized and nonpolarized cells: a pathway independent of the endoplasmic reticulum-Golgi complexQ42505508
Dynamin: a molecular motor with pinchase actionQ47720834
FKBP-12 recognition is dispensable for signal generation by type I transforming growth factor-beta receptors.Q52521102
EndocytosisQ57374715
Hemopexin joins transferrin as representative members of a distinct class of receptor-mediated endocytic transport systemsQ68077587
Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblastsQ72389967
Differential requirement for type I and type II transforming growth factor beta receptor kinase activity in ligand-mediated receptor endocytosisQ77172105
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)675-684
P577publication date2001-03-01
P1433published inMolecular Biology of the CellQ2338259
P1476titleMechanisms of transforming growth factor-beta receptor endocytosis and intracellular sorting differ between fibroblasts and epithelial cells
P478volume12