scholarly article | Q13442814 |
P50 | author | Eric Lander | Q970550 |
Tyler Jacks | Q7860044 | ||
Gordon B. Mills | Q28086262 | ||
Katherine Stemke-Hale | Q52353554 | ||
Jesse S Boehm | Q55297546 | ||
William C Hahn | Q88192808 | ||
David E Root | Q89000283 | ||
Levi A Garraway | Q89916155 | ||
David A Barbie | Q106943892 | ||
Anna C Schinzel | Q106944160 | ||
Ana Maria Gonzalez-Angulo | Q107718318 | ||
Bryan T. Hennessy | Q117214243 | ||
P2093 | author name string | Aysegul A Sahin | |
Qing Sheng | |||
Yiling Lu | |||
Ian F Dunn | |||
Jan H Reiling | |||
Peter Sandy | |||
So Young Kim | |||
William R Sellers | |||
Michael A Davies | |||
Bhaskar Dutta | |||
Lucia E Rameh | |||
Ana Lluch | |||
Sebastian Hoersch | |||
Piyush B Gupta | |||
Serena Silver | |||
Rosalia Rabinovsky | |||
Corwin Joy | |||
Hsiuyi Tseng | |||
Panisa Pochanard | |||
Krishna M Vasudevan | |||
Jessica J Kim | |||
Chontelle J McNear | |||
P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4 | Q24298867 | ||
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) | Q24324148 | ||
Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1 | Q24531380 | ||
Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo | Q24531714 | ||
The PI3K-PDK1 connection: more than just a road to PKB | Q24531972 | ||
A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation | Q24534951 | ||
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes | Q24647928 | ||
Knockin of mutant PIK3CA activates multiple oncogenic pathways | Q24657412 | ||
Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1 | Q27331645 | ||
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer | Q27646556 | ||
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic | Q27824826 | ||
Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling | Q27851446 | ||
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain | Q27865182 | ||
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B | Q28116107 | ||
High frequency of mutations of the PIK3CA gene in human cancers | Q28131776 | ||
Synthesis and function of 3-phosphorylated inositol lipids | Q28200755 | ||
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 | ||
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism | Q29547302 | ||
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt | Q29547767 | ||
The phosphatidylinositol 3-Kinase AKT pathway in human cancer | Q29547860 | ||
Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 | ||
BRAF mutation predicts sensitivity to MEK inhibition | Q29614281 | ||
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen | Q29615061 | ||
Statistical practice in high-throughput screening data analysis | Q31032001 | ||
Integrative genomic approaches identify IKBKE as a breast cancer oncogene | Q33287979 | ||
Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate | Q33948936 | ||
The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells | Q34234737 | ||
The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1. | Q34328370 | ||
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. | Q35757521 | ||
Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools | Q36255578 | ||
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans | Q37111299 | ||
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer | Q37187915 | ||
Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK. | Q37194222 | ||
Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis | Q37360125 | ||
Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. | Q39457088 | ||
A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition. | Q39979475 | ||
Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells | Q40220260 | ||
Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. | Q40264478 | ||
Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells | Q40345016 | ||
High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma | Q40345165 | ||
Mutant PIK3CA promotes cell growth and invasion of human cancer cells | Q40410776 | ||
A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. | Q40875073 | ||
Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction | Q40957062 | ||
Identification of a specific DNA region required for enhanced transcription of HER2/neu in the MDA-MB453 breast cancer cell line | Q41171448 | ||
Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation | Q41709294 | ||
Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer | Q43675669 | ||
Labeling anti-HER2/neu monoclonal antibodies with 111In and 90Y using a bifunctional DTPA chelating agent | Q44572339 | ||
Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival | Q46546762 | ||
Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice | Q46768791 | ||
Comparative gene marker selection suite | Q48446590 | ||
Morphological and immunocytochemical characteristics of human tumor cell lines for use in a disease-oriented anticancer drug screen | Q48461163 | ||
Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of protein kinase Calpha. | Q52828939 | ||
The PI 3-kinase isoforms p110(alpha) and p110(beta) have differential roles in PDGF- and insulin-mediated signaling | Q73348939 | ||
EGFR and ErbB2 differentially regulate Raf-1 translocation and activation | Q77505441 | ||
Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas | Q81463881 | ||
P433 | issue | 1 | |
P304 | page(s) | 21-32 | |
P577 | publication date | 2009-07-01 | |
P1433 | published in | Cancer Cell | Q280018 |
P1476 | title | AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer | |
P478 | volume | 16 |