| P50 | author | Eric Lander | Q970550 |
| | Tyler Jacks | Q7860044 |
| | Gordon B. Mills | Q28086262 |
| | Katherine Stemke-Hale | Q52353554 |
| | Jesse S Boehm | Q55297546 |
| | William C Hahn | Q88192808 |
| | David E Root | Q89000283 |
| | Levi A Garraway | Q89916155 |
| | David A Barbie | Q106943892 |
| | Anna C Schinzel | Q106944160 |
| | Ana Maria Gonzalez-Angulo | Q107718318 |
| | Bryan T. Hennessy | Q117214243 |
| P2093 | author name string | Aysegul A Sahin | |
| | Qing Sheng | |
| | Yiling Lu | |
| | Ian F Dunn | |
| | Jan H Reiling | |
| | Peter Sandy | |
| | So Young Kim | |
| | William R Sellers | |
| | Michael A Davies | |
| | Bhaskar Dutta | |
| | Lucia E Rameh | |
| | Ana Lluch | |
| | Sebastian Hoersch | |
| | Piyush B Gupta | |
| | Serena Silver | |
| | Rosalia Rabinovsky | |
| | Corwin Joy | |
| | Hsiuyi Tseng | |
| | Panisa Pochanard | |
| | Krishna M Vasudevan | |
| | Jessica J Kim | |
| | Chontelle J McNear | |
| P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
| | Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 |
| | CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4 | Q24298867 |
| | mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) | Q24324148 |
| | Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1 | Q24531380 |
| | Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo | Q24531714 |
| | The PI3K-PDK1 connection: more than just a road to PKB | Q24531972 |
| | A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation | Q24534951 |
| | A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes | Q24647928 |
| | Knockin of mutant PIK3CA activates multiple oncogenic pathways | Q24657412 |
| | Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1 | Q27331645 |
| | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer | Q27646556 |
| | Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic | Q27824826 |
| | Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling | Q27851446 |
| | Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain | Q27865182 |
| | Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B | Q28116107 |
| | High frequency of mutations of the PIK3CA gene in human cancers | Q28131776 |
| | Synthesis and function of 3-phosphorylated inositol lipids | Q28200755 |
| | Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 |
| | The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism | Q29547302 |
| | mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt | Q29547767 |
| | The phosphatidylinositol 3-Kinase AKT pathway in human cancer | Q29547860 |
| | Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 |
| | BRAF mutation predicts sensitivity to MEK inhibition | Q29614281 |
| | A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen | Q29615061 |
| | Statistical practice in high-throughput screening data analysis | Q31032001 |
| | Integrative genomic approaches identify IKBKE as a breast cancer oncogene | Q33287979 |
| | Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate | Q33948936 |
| | The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells | Q34234737 |
| | The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1. | Q34328370 |
| | Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. | Q35757521 |
| | Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools | Q36255578 |
| | Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans | Q37111299 |
| | An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer | Q37187915 |
| | Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK. | Q37194222 |
| | Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis | Q37360125 |
| | Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. | Q39457088 |
| | A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition. | Q39979475 |
| | Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells | Q40220260 |
| | Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. | Q40264478 |
| | Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells | Q40345016 |
| | High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma | Q40345165 |
| | Mutant PIK3CA promotes cell growth and invasion of human cancer cells | Q40410776 |
| | A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. | Q40875073 |
| | Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction | Q40957062 |
| | Identification of a specific DNA region required for enhanced transcription of HER2/neu in the MDA-MB453 breast cancer cell line | Q41171448 |
| | Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation | Q41709294 |
| | Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer | Q43675669 |
| | Labeling anti-HER2/neu monoclonal antibodies with 111In and 90Y using a bifunctional DTPA chelating agent | Q44572339 |
| | Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival | Q46546762 |
| | Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice | Q46768791 |
| | Comparative gene marker selection suite | Q48446590 |
| | Morphological and immunocytochemical characteristics of human tumor cell lines for use in a disease-oriented anticancer drug screen | Q48461163 |
| | Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of protein kinase Calpha. | Q52828939 |
| | The PI 3-kinase isoforms p110(alpha) and p110(beta) have differential roles in PDGF- and insulin-mediated signaling | Q73348939 |
| | EGFR and ErbB2 differentially regulate Raf-1 translocation and activation | Q77505441 |
| | Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas | Q81463881 |
| P433 | issue | 1 | |
| P304 | page(s) | 21-32 | |
| P577 | publication date | 2009-07-01 | |
| P1433 | published in | Cancer Cell | Q280018 |
| P1476 | title | AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer | |
| P478 | volume | 16 | |