Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine.

scientific article

Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/CS20110060
P932PMC publication ID3097472
P698PubMed publication ID21446920
P5875ResearchGate publication ID50906538

P50authorSatish C. KalhanQ39880297
P2093author name stringRocio Lopez
Srinivasan Dasarathy
Carole Bennett
Susan Marczewski
Clarita Duenas
Lourdes L Gruca
John Edmison
P2860cites workPioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitisQ24625697
Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acidQ28568042
Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liverQ28581508
Steatohepatitis: a tale of two "hits"?Q29547771
Design and validation of a histological scoring system for nonalcoholic fatty liver diseaseQ29614930
Molecular mediators of hepatic steatosis and liver injuryQ29616709
Nonalcoholic fatty liver diseaseQ29619354
Plasma total homocysteine concentrations are unrelated to insulin sensitivity and components of the metabolic syndrome in healthy men.Q31831292
Methionine metabolism in human pregnancyQ33592333
Mutations in human glycine N-methyltransferase give insights into its role in methionine metabolismQ34111150
Methionine kinetics and balance at the 1985 FAO/WHO/UNU intake requirement in adult men studied with L-[2H3-methyl-1-13C]methionine as a tracerQ67924100
Rapid assay for amino acids in serum or urine by pre-column derivatization and reversed-phase liquid chromatographyQ70307472
Gas chromatography/mass spectrometric determination of [15N]urea in plasma and application to urea metabolism studyQ70328452
Regulation by hypoxia of methionine adenosyltransferase activity and gene expression in rat hepatocytesQ74133491
Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the ratQ77628584
Urinary urea nitrogen excretion during the hyperinsulinemic euglycemic clamp in type 1 diabetic patients and healthy subjectsQ80438615
Effects of insulin deprivation and treatment on homocysteine metabolism in people with type 1 diabetesQ83986297
S-adenosyl-L-methionine: its role in the treatment of liver disordersQ34157914
Methionine metabolism in mammalsQ34366989
Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activationQ34378959
Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidationQ34512108
Hepatic glycine N-methyltransferase is up-regulated by excess dietary methionine in ratsQ34526967
Insulin-mediated reduction of whole body protein breakdown. Dose-response effects on leucine metabolism in postabsorptive menQ34569585
Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic ConferenceQ35115696
Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferationQ35885731
Skeletal muscle cytokines: regulation by pathogen-associated molecules and catabolic hormonesQ36089013
Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it.Q36365999
Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis.Q36366205
Role of S-adenosyl-L-methionine in liver health and injuryQ36804166
Muscle protein synthesis and balance responsiveness to essential amino acids ingestion in the presence of elevated plasma free fatty acid concentrationsQ37315753
Non-alcoholic steatohepatitis and animal models: understanding the human disease.Q37332814
Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusionQ37337683
Metabolic disturbances in non-alcoholic fatty liver disease.Q37401367
Preliminary report: inhibition of cellular proteasome activity by free fatty acidsQ39855345
Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liverQ40340319
INFLUENCE OF PANCREATIC HORMONES ON ENZYMES CONCERNED WITH UREA SYNTHESIS IN RAT LIVERQ41996333
Modulation of rat liver S-adenosylmethionine synthetase activity by glutathioneQ42081009
Effect of enteral glutamine or glycine on whole-body nitrogen kinetics in very-low-birth-weight infantsQ42457684
Increased sensitivity to oxidative injury in chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA.Q42984350
Fatty acids, insulin resistance, and protein metabolismQ43065429
Measurement of intracellular sulfur amino acid metabolism in humansQ43606115
Fasting plasma homocysteine levels in the insulin resistance syndrome: the Framingham offspring studyQ43687912
Regional muscle and adipose tissue amino acid metabolism in lean and obese women.Q43908164
Unexpected inverse relationship between insulin resistance and serum homocysteine in healthy subjects.Q44032553
Plasma total homocysteine quantification: an improvement of the classical high-performance liquid chromatographic method with fluorescence detection of the thiol-SBD derivativesQ44166405
Insulin sensitivity and plasma homocysteine concentrations in non-diabetic obese and normal weight subjectsQ44346414
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionineQ44378796
Quantitative study in vivo of methionine cycle in humans using [methyl-2H3]- and [1-13C]methionineQ44494347
Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patientsQ44615824
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donorQ44618189
Changes in basal and insulin and amino acid response of whole body and skeletal muscle proteins in obese men.Q45995936
Hyperhomocysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children.Q46833327
Insulin resistance of protein metabolism in type 2 diabetesQ46947811
Whole-body protein anabolic response is resistant to the action of insulin in obese womenQ47750498
Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats.Q48003280
Plasma total homocysteine levels in subjects with hyperinsulinemia.Q51558073
Acute hyperinsulinemia reduces plasma concentrations of homocysteine in healthy men.Q51562858
Glucagon immunoneutralization in diabetic rats normalizes urea synthesis and decreases nitrogen wasting.Q51607374
Calculation of substrate turnover rate in stable isotope tracer studies.Q52433177
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectsteatohepatitisQ2335423
non-alcoholic steatohepatitisQ28692677
P304page(s)179-189
P577publication date2011-08-01
P1433published inClinical ScienceQ372419
P1476titleMethionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine
P478volume121

Reverse relations

cites work (P2860)
Q36174255Altered arsenic disposition in experimental nonalcoholic fatty liver disease
Q91780954Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease
Q21559453Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains
Q35208556Consequences of PPAR(α) Invalidation on Glutathione Synthesis: Interactions with Dietary Fatty Acids.
Q35760391Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease
Q37419162Foetal programming by methyl donor deficiency produces steato-hepatitis in rats exposed to high fat diet.
Q35120259High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.
Q42601503Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism
Q104064325Methionine metabolism in chronic liver diseases: an update on molecular mechanism and therapeutic implication
Q28071265Molecular Pathogenesis of NASH
Q26992163Nonalcoholic fatty liver disease: update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine
Q35380845Potential epigenetic mechanism in non-alcoholic Fatty liver disease
Q55135320Role of Aramchol in steatohepatitis and fibrosis in mice.
Q26829356S-adenosylmethionine (SAMe) therapy in liver disease: a review of current evidence and clinical utility
Q34306534S-adenosylmethionine in liver health, injury, and cancer
Q36332941S-adenosylmethionine-dependent protein methylation is required for expression of selenoprotein P and gluconeogenic enzymes in HepG2 human hepatocytes
Q34483949Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat
Q56507986The Cholesterol Derivative 27-Hydroxycholesterol Reduces Steatohepatitis in Mice
Q35123495The metabolically benign and malignant fatty liver
Q36581749Whole body creatine and protein kinetics in healthy men and women: effects of creatine and amino acid supplementation