review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1015209834 |
P356 | DOI | 10.1385/NMM:2:2:115 |
P698 | PubMed publication ID | 12428807 |
P50 | author | Poul Henning Jensen | Q60892576 |
P2093 | author name string | Simon Lykkebo | |
P2860 | cites work | alpha-Synuclein immunoreactivity in dementia with Lewy bodies: morphological staging and comparison with ubiquitin immunostaining | Q73727325 |
Alpha-synuclein. Axonal transport, ligand interaction and neurodegeneration | Q74012461 | ||
Neuropathology in mice expressing human alpha-synuclein | Q74139704 | ||
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions | Q22009563 | ||
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization | Q24291150 | ||
Tubulin seeds alpha-synuclein fibril formation | Q24291881 | ||
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease | Q24321355 | ||
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
Alpha-synuclein in Lewy bodies | Q27860680 | ||
Synucleins are a novel class of substrates for G protein-coupled receptor kinases | Q28138274 | ||
Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein | Q28141645 | ||
Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filaments | Q28141728 | ||
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I | Q28141879 | ||
Protein-protein interactions of alpha-synuclein in brain homogenates and transfected cells | Q28202923 | ||
Alpha-synuclein and neurodegenerative diseases | Q28204386 | ||
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain | Q28509158 | ||
Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons | Q28567029 | ||
Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form | Q28567172 | ||
Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein | Q28587358 | ||
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system | Q28594502 | ||
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease | Q29547175 | ||
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders | Q29614754 | ||
A Drosophila model of Parkinson's disease | Q29617052 | ||
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes | Q29617606 | ||
Kinesin and dynein superfamily proteins and the mechanism of organelle transport | Q29620418 | ||
Widespread alterations of alpha-synuclein in multiple system atrophy | Q30444927 | ||
Cytoplasmic dynein is associated with slow axonal transport | Q30453931 | ||
Delayed localization of synelfin (synuclein, NACP) to presynaptic terminals in cultured rat hippocampal neurons | Q30470224 | ||
The rat brain synucleins; family of proteins transiently associated with neuronal membrane | Q33240068 | ||
Report of the second dementia with Lewy body international workshop: diagnosis and treatment. Consortium on Dementia with Lewy Bodies | Q33738072 | ||
Amyloid fibrillogenesis: themes and variations | Q33840755 | ||
alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356. | Q33872332 | ||
Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations | Q33893738 | ||
alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins | Q33929879 | ||
Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra | Q33938966 | ||
Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. | Q33941736 | ||
Co-association of parkin and alpha-synuclein | Q34093915 | ||
alpha-Synuclein is phosphorylated in synucleinopathy lesions | Q34111460 | ||
Synucleinopathies: clinical and pathological implications | Q34140347 | ||
Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded | Q34175381 | ||
Assignment of human alpha-synuclein (SNCA) and beta-synuclein (SNCB) genes to chromosomes 4q21 and 5q35. | Q34295323 | ||
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch. | Q34303003 | ||
Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid | Q34314680 | ||
Alpha-synuclein and the Lewy body disorders | Q34318165 | ||
The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system | Q34318718 | ||
Identification of two distinct synucleins from human brain | Q34341909 | ||
The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons | Q34370362 | ||
Kinesin, dynein and neurofilament transport | Q34416231 | ||
Slow axonal transport: fast motors in the slow lane. | Q34495166 | ||
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy | Q34964783 | ||
Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model | Q35747138 | ||
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies. | Q35764504 | ||
Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal | Q36455215 | ||
??? | Q64767196 | ||
Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein | Q36677512 | ||
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded | Q36830682 | ||
Oxygen free radicals and Parkinson's disease | Q37693669 | ||
Retention and redistribution of proteins in mammalian nerve fibres by axoplasmic transport | Q39366873 | ||
Ultrastructural localization of the vesicular monoamine transporter-2 in midbrain dopaminergic neurons: potential sites for somatodendritic storage and release of dopamine. | Q39757944 | ||
The neuronal cytoskeleton: roles in neuronal morphogenesis and organelle transport. | Q40399871 | ||
Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein | Q40763309 | ||
Induction of alpha-synuclein aggregation by intracellular nitrative insult. | Q40776570 | ||
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease | Q40795664 | ||
Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr-alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells | Q40882515 | ||
Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins | Q41043578 | ||
The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease | Q41359019 | ||
Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro | Q41646793 | ||
alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease | Q41676981 | ||
Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid | Q42620617 | ||
Conformational properties of alpha-synuclein in its free and lipid-associated states | Q43564642 | ||
alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome | Q43816254 | ||
Cytosolic O-glycosylation is abundant in nerve terminals | Q43820039 | ||
Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation | Q43832078 | ||
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system. | Q43940212 | ||
Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development | Q43995715 | ||
Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease? | Q45300712 | ||
Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease | Q46084408 | ||
Identification, localization and characterization of the human gamma-synuclein gene | Q48023048 | ||
Neural expression profile of alpha-synuclein in developing human cortex | Q48097777 | ||
Developmental expression of alpha-synuclein in rat hippocampus and cerebral cortex | Q48189089 | ||
The Lewy body in Parkinson's disease. | Q48254020 | ||
Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy | Q48342277 | ||
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease | Q48353748 | ||
Synthetic filaments assembled from C-terminally truncated alpha-synuclein | Q48360396 | ||
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. | Q48384247 | ||
Multiple-system atrophy: a new alpha-synuclein disease? | Q48406192 | ||
Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. | Q48830095 | ||
Distribution of phosphoneuroprotein 14 (PNP 14) in vertebrates: its levels as determined by enzyme immunoassay. | Q48858580 | ||
Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system. | Q48958079 | ||
Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis. | Q52165843 | ||
Cell and tissue distribution and developmental change of neuron specific 14 kDa protein (phosphoneuroprotein 14). | Q52222873 | ||
Membrane binding and self-association of alpha-synucleins. | Q52543652 | ||
Metal-catalyzed oxidation of alpha-synuclein in the presence of Copper(II) and hydrogen peroxide. | Q53235896 | ||
Nonsaturable binding indicates clustering of tau on the microtubule surface in a paired helical filament-like conformation. | Q53236118 | ||
Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro | Q64865343 | ||
Alpha-synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components | Q73120774 | ||
Axonal transport of synucleins is mediated by all rate components | Q73189158 | ||
Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies | Q73626218 | ||
P433 | issue | 2 | |
P921 | main subject | Parkinson's disease | Q11085 |
Synuclein | Q24767155 | ||
P304 | page(s) | 115-129 | |
P577 | publication date | 2002-01-01 | |
P1433 | published in | NeuroMolecular Medicine | Q15716731 |
P1476 | title | Alpha-synuclein and presynaptic function: implications for Parkinson's disease | |
P478 | volume | 2 |
Q47069000 | A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress |
Q44852323 | Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice. |
Q36063269 | Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease |
Q89529472 | Alternative Structures of α-Synuclein |
Q36527246 | Calcium(II) selectively induces alpha-synuclein annular oligomers via interaction with the C-terminal domain |
Q42705823 | Exogenous Alpha-Synuclein Alters Pre- and Post-Synaptic Activity by Fragmenting Lipid Rafts |
Q42119505 | GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein. |
Q38647359 | Macroautophagy and the proteasome are differently involved in the degradation of alpha-synuclein wild type and mutated A30P in an in vitro inducible model (PC12/TetOn). |
Q36100354 | Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease |
Q38488082 | Mechanisms of alpha-synuclein action on neurotransmission: cell-autonomous and non-cell autonomous role |
Q39998122 | RNA interference mediated silencing of alpha-synuclein in MN9D cells and its effects on cell viability |
Q38038126 | Recent advances in α-synuclein functions, advanced glycation, and toxicity: implications for Parkinson's disease |
Q53875651 | Regional distribution of proteinase K-resistant alpha-synuclein correlates with Lewy body disease stage. |
Q33326619 | Retracted: DJ-1 Modulates α-Synuclein Aggregation State in a Cellular Model of Oxidative Stress: Relevance for Parkinson's Disease and Involvement of HSP70 |
Q36700077 | Silencing alpha-synuclein gene expression enhances tyrosine hydroxylase activity in MN9D cells |
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