A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo

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A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2010-12-325357
P932PMC publication ID3099576
P698PubMed publication ID21378272
P5875ResearchGate publication ID50289463

P2093author name stringJames Palis
Jane Little
Jenna M Frame
Kathleen E McGrath
Michael Bulger
Paul D Kingsley
Anne D Koniski
George J Fromm
P2860cites workDisruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesisQ24567977
Sox6 directly silences epsilon globin expression in definitive erythropoiesisQ25257856
Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liverQ28210389
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesisQ28273478
Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1Q28295662
Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLFQ28301573
Developmental and species-divergent globin switching are driven by BCL11AQ28506497
Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF geneQ28507914
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1Q28508495
CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryoQ28510397
The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stabilityQ28591101
The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesisQ30478945
Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetusQ30481223
Investigations of a human embryonic globin gene silencing element using YAC transgenic miceQ33616785
Control of globin gene expression during development and erythroid differentiationQ33645104
Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.Q33788501
Aorta-associated CD34+ hematopoietic cells in the early human embryoQ34370051
A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locusQ35161605
Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesisQ35268731
Human embryonic hemopoiesis. Kinetics of progenitors and precursors underlying the yolk sac----liver transitionQ35807649
Embryonic----Fetal Hb switch in humans: studies on erythroid bursts generated by embryonic progenitors from yolk sac and liverQ36257439
Stem cell emergence and hemopoietic activity are incompatible in mouse intraembryonic sites.Q36375078
Primitive erythropoiesis and megakaryopoiesis in the yolk sac are independent of c-mybQ36478451
Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genesQ36479638
All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac.Q36508856
The fetal liver is a niche for maturation of primitive erythroid cellsQ36638751
Ontogeny of erythropoiesis in the mammalian embryo.Q37087619
Multispectral imaging of hematopoietic cells: where flow meets morphologyQ37186175
Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryoQ37327026
Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming.Q37351050
Advances in the understanding of haemoglobin switchingQ37702418
Development of hematopoietic stem cell activity in the mouse embryoQ38306839
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesisQ38335144
"Maturational" globin switching in primary primitive erythroid cellsQ42022132
Mouse placenta is a major hematopoietic organ.Q44595212
Haemoglobin switching in human embryos: asynchrony of zeta----alpha and epsilon----gamma-globin switches in primitive and definite erythropoietic lineageQ44788049
Protein Synthesis: Its Control in ErythropoiesisQ44790834
Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesisQ44805529
Analysis of hematopoietic progenitors in the mouse embryoQ45113266
Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms.Q45940230
Stem cell factor induces proliferation and differentiation of fetal progenitor cells in the mouseQ47801658
Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo.Q51036829
Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse.Q51085122
Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice.Q52178086
Coexpression of embryonic, fetal, and adult globins in erythroid cells of human embryos: relevance to the cell-lineage models of globin switchingQ69002233
On the kinetics of erythroid cell differentiation in fetal mice. I. Microspectrophotometric determination of the hemoglobin content in erythroid cells during gestationQ69580931
Hemoglobin switching during murine embryonic development: evidence for two populations of embryonic erythropoietic progenitor cellsQ70012813
Expansion of hematopoietic stem cells in the developing liver of a mouse embryoQ73584800
Circulation is established in a stepwise pattern in the mammalian embryoQ78447724
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)4600-4608
P577publication date2011-03-04
P1433published inBloodQ885070
P1476titleA transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo
P478volume117

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