Prostaglandins and other lipid mediators in Alzheimer's disease

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Prostaglandins and other lipid mediators in Alzheimer's disease is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S0090-6980(02)00031-X
P698PubMed publication ID12432919

P50authorWalter J LukiwQ92649708
P2093author name stringNicolas G Bazan
Vittorio Colangelo
P2860cites workApolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer diseaseQ22248076
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's diseaseQ24316501
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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairmentQ29547294
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid proteinQ29547803
Cyclooxygenases 1 and 2Q29615645
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptorQ29618322
Prostaglandin endoperoxide synthase gene structure: identification of the transcriptional start site and 5'-flanking regulatory sequencesQ31111891
Cyclooxygenase-2 stimulates production of amyloid beta-peptide in neuroblastoma x glioma hybrid NG108-15 cellsQ31953588
VAMP-1: a synaptic vesicle-associated integral membrane proteinQ33583102
Inflammation of the brain in Alzheimer's disease: implications for therapy.Q33594683
Neurofilament functions in health and diseaseQ33745290
Regulation of platelet-activating factor (PAF) activity in human diseases by phospholipase A2 inhibitors, PAF acetylhydrolases, PAF receptor antagonists and free radical scavengersQ33745976
The biological and pathological function of presenilin proteins--simple cell systems and a worm in Alzheimer's disease researchQ33827602
Apolipoprotein E: a pharmacogenetic target for the treatment of Alzheimer's diseaseQ33835902
Cellular and molecular basis of beta-amyloid precursor protein metabolismQ33854048
Molecular genetics of Alzheimer diseaseQ33862540
Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal cultureQ33892828
Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient miceQ33893148
Neuroinflammatory signaling upregulation in Alzheimer's diseaseQ34074190
Isoprostanes, novel markers of oxidative injury, help understanding the pathogenesis of neurodegenerative diseases.Q34074245
Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's diseaseQ34263082
Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures.Q48828436
Cytoskeletal messenger RNA stability in human neocortex: studies in normal aging and in Alzheimer's disease.Q48852765
Prostaglandin G/H synthase-2 (cyclooxygenase-2) mRNA expression is decreased in Alzheimer's disease.Q48925866
Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain.Q48987995
Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons.Q52002767
Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.Q52020137
Discordance and concordance of dementia of the Alzheimer type (DAT) in monozygotic twins indicate heritable and sporadic forms of Alzheimer's disease.Q52048176
Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study.Q52884779
Dementia of the Alzheimer type: clinical and family study of 22 twin pairs.Q53195030
Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution.Q53203859
Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons.Q53231397
Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia.Q53236835
Clinical trial of indomethacin in Alzheimer's disease.Q53318286
beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.Q54447659
Regulation of cyclooxygenase-2 expression in human mesangial cells - transcriptional inhibition by IL-13Q58869434
Neurofilaments in health and diseaseQ64869492
Cyclooxygenase-2 induction in cerebral cortex: an intracellular response to synaptic excitationQ70790738
Interleukin-1 beta induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte culturesQ71082285
Enhanced processing of APP induced by IL-1 beta can be reduced by indomethacin and nordihydroguaiaretic acidQ72108160
Effects of phospholipase A2 inhibitors on Ca2+ oscillations in pancreatic acinar cellsQ73343473
COX-2 as a multifunctional neuronal modulatorQ73704223
Interferon-gamma and interleukin 4 inhibit interleukin 1beta-induced delayed prostaglandin E(2)generation through suppression of cyclooxygenase-2 expression in human fibroblastsQ73869344
COX-1 and COX-2 in health and diseaseQ87469049
Cyclooxygenase and Alzheimer's disease: implications for preventive initiatives to slow the progression of clinical dementiaQ34312617
Genomic structure and expression of STM2, the chromosome 1 familial Alzheimer disease geneQ34383870
Analysis of the 5' sequence, genomic structure, and alternative splicing of the presenilin-1 gene (PSEN1) associated with early onset Alzheimer diseaseQ34419817
Methodological variables in the assessment of beta amyloid neurotoxicityQ35582072
Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2Q35787852
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.Q35969894
Expression profiles of multiple genes in single neurons of Alzheimer's diseaseQ36270250
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's diseaseQ36415791
Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activityQ36415795
Aggregation State and Neurotoxic Properties of Alzheimer Beta-Amyloid PeptideQ36686197
Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.Q36753784
Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesisQ37083425
COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortexQ37691478
Arachidonic acid cascade and signal transductionQ37815882
Risk of Alzheimer's disease and duration of NSAID use.Q39457609
Neurofilament function and dysfunction: involvement in axonal growth and neuronal diseaseQ40388310
Synaptic vesicle proteins and regulated exocytosis.Q40418217
Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease.Q40820802
Mediators of injury in neurotrauma: intracellular signal transduction and gene expressionQ40965329
The effect of nitric oxide on cytokine-induced release of PGE2 by human cultured astroglial cellsQ41019496
The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's diseaseQ41036442
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studiesQ41075378
Prostaglandin E2 induces interleukin-6 synthesis in human astrocytoma cells.Q41131861
Excitotoxic neurodegeneration in Alzheimer disease. New hypothesis and new therapeutic strategiesQ41619176
Cyclooxygenases and the central nervous systemQ41646498
Subcellular membrane impairment and application of phospholipase A2 inhibitors in endotoxic shockQ41923779
Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoidsQ42506522
Effects of protein kinase C activation on prostaglandin production and cyclooxygenase mRNA levels in ovine astrogliaQ42524729
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.Q43638880
Arachidonic acid and its metabolites in cerebral ischemiaQ44419491
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly stateQ44689258
A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitorsQ46046983
Transforming growth factor beta1 regulates the expression of cyclooxygenase in cultured cortical astrocytes and neurons.Q47777972
Patterns of cyclooxygenase-1 and -2 expression in human gliomas in vivoQ48114757
Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organsQ48188389
Expression of proteins linked to exocytosis and neurotransmission in patients with Creutzfeldt-Jakob diseaseQ48200986
Quantitative decrease in synaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tanglesQ48240552
Identical twins discordant for presenile dementia of the Alzheimer typeQ48289623
The neuromessenger platelet-activating factor in plasticity and neurodegeneration.Q48290832
Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility icebergQ48293119
Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brainsQ48298397
Synapsin I gene expression in the adult rat brain with comparative analysis of mRNA and protein in the hippocampusQ48344995
Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brainQ48394369
Temporal cortex synaptophysin mRNA is reduced in Alzheimer's disease and is negatively correlated with the severity of dementia.Q48461292
Regional distribution of prostaglandin H synthase-2 and neuronal nitric oxide synthase in piglet brain.Q48470743
Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging.Q48480334
Widespread peroxynitrite-mediated damage in Alzheimer's disease.Q48728343
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
P304page(s)197-210
P577publication date2002-08-01
P1433published inProstaglandins and Other Lipid MediatorsQ15754476
P1476titleProstaglandins and other lipid mediators in Alzheimer's disease
P478volume68-69

Reverse relations

cites work (P2860)
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