scholarly article | Q13442814 |
P50 | author | Weiguang Wang | Q43084075 |
P2093 | author name string | A L Armesilla | |
S Brown | |||
B Xu | |||
P Liu | |||
J Cassidy | |||
J L Darling | |||
V Kannappan | |||
I S Fombon | |||
N C Yip | |||
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Disulfiram-mediated inhibition of NF-kappaB activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines | Q40670865 | ||
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Copper and zinc levels in normal and malignant tissues | Q41607676 | ||
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Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics | Q43041593 | ||
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Suppressing glioblastoma stem cell function by aldehyde dehydrogenase inhibition with chloramphenicol or disulfiram as a new treatment adjunct: an hypothesis. | Q45981295 | ||
Phase I study of bortezomib with weekly paclitaxel in patients with advanced solid tumours. | Q46474270 | ||
Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity | Q48381026 | ||
Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay. | Q50886497 | ||
Targeting breast cancer stem cells | Q57139325 | ||
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Trace-metal analysis of cancerous and noncancerous human tissues | Q68629379 | ||
Selective protection against cis-diamminedichloroplatinum(II)-induced toxicity in kidney, gut, and bone marrow by diethyldithiocarbamate | Q70137123 | ||
Comparison between concentrations of trace elements in normal and neoplastic human breast tissue | Q70641092 | ||
Dithiocarbamates Induce Apoptosis in Thymocytes by Raising the Intracellular Level of Redox-active Copper | Q71823842 | ||
Modification of the sensitivity and repair of potentially lethal damage by diethyldithiocarbamate during and following exposure of plateau-phase cultures of mammalian cells to radiation and cis-diamminedichloroplatinum(II) | Q72935637 | ||
Effect of disulfiram (tetraethylthiuram disulfide) amd diethyldithiocarbamate on the bladder toxicity and antitumor activity of cyclophosphamide in mice | Q72957176 | ||
Inhibition of recombinant human mitochondrial and cytosolic aldehyde dehydrogenases by two candidates for the active metabolites of disulfiram | Q73838734 | ||
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily | Q24655095 | ||
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome | Q24657877 | ||
ALDH3A1: a corneal crystallin with diverse functions | Q28248140 | ||
Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients | Q28267360 | ||
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors | Q29547463 | ||
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer | Q29614599 | ||
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation | Q29618715 | ||
Cancer stem cells: models and concepts | Q29620611 | ||
High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth | Q33507489 | ||
TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype | Q34130168 | ||
Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer | Q34420393 | ||
Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy | Q34588238 | ||
Clonogenic assay of cells in vitro. | Q34615431 | ||
Human aldehyde dehydrogenases: potential pathological, pharmacological, and toxicological impact | Q35077713 | ||
A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites | Q35625458 | ||
Reactive oxygen species mediate crosstalk between NF-kappaB and JNK. | Q36337991 | ||
NF-kappaB activation by reactive oxygen species: fifteen years later | Q36488422 | ||
Reactive oxygen species-induced activation of the MAP kinase signaling pathways | Q36598861 | ||
Current insights into the regulation of programmed cell death by NF-kappaB. | Q36637900 | ||
Reactive oxygen species: a breath of life or death? | Q36731940 | ||
Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase. | Q36767402 | ||
Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival | Q37015135 | ||
Inhibition of tumor proteasome activity by gold-dithiocarbamato complexes via both redox-dependent and -independent processes | Q37158093 | ||
Elevated copper and oxidative stress in cancer cells as a target for cancer treatment | Q37262037 | ||
Finding cancer stem cells: are aldehyde dehydrogenases fit for purpose? | Q37789712 | ||
Constitutive nuclear factor-kappa B mRNA, protein overexpression and enhanced DNA-binding activity in thymidylate synthase inhibitor-resistant tumour cells | Q38310149 | ||
Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells. | Q38334174 | ||
Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis | Q39600418 | ||
Relationships between multidrug resistance (MDR) and stem cell markers in human chronic myeloid leukemia cell lines. | Q39765844 | ||
Disulfiram induces copper-dependent stimulation of reactive oxygen species and activation of the extrinsic apoptotic pathway in melanoma | Q39766253 | ||
Triptolide simultaneously induces reactive oxygen species, inhibits NF-kappaB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines | Q39776662 | ||
Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines. | Q39794951 | ||
The actions of metabolic fate of disulfiram | Q40307000 | ||
Bortezomib (VELCADE) in metastatic breast cancer: pharmacodynamics, biological effects, and prediction of clinical benefits | Q40359103 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | breast cancer | Q128581 |
neoplastic stem cells | Q1638475 | ||
P304 | page(s) | 1564-1574 | |
P577 | publication date | 2011-04-12 | |
P1433 | published in | British Journal of Cancer | Q326309 |
P1476 | title | Disulfiram modulated ROS-MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties | |
P478 | volume | 104 |
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