Constitutive HIF-1α expression blunts the beneficial effects of cardiosphere-derived cell therapy in the heart by altering paracrine factor balance

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Constitutive HIF-1α expression blunts the beneficial effects of cardiosphere-derived cell therapy in the heart by altering paracrine factor balance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12265-011-9265-3
P932PMC publication ID3104856
P698PubMed publication ID21538185
P5875ResearchGate publication ID51094148

P2093author name stringVenu Raman
Andreas Barth
D Brian Foster
Theodore P Abraham
Peihong Dong
Aurelio Pinheiro
John Terrovitis
Connie Yachan Chang
Maria Roselle Abraham
Michael Bonios
Miguel Santaularia
P2860cites workHypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factorsQ24320033
Bone marrow cells regenerate infarcted myocardiumQ28210640
Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau proteinQ28269238
Hydroxylation of HIF-1: oxygen sensing at the molecular levelQ28276549
Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1Q28282227
Identification and functionality of proteomes secreted by rat cardiac stem cells and neonatal cardiomyocytesQ28573603
A novel potent vasoconstrictor peptide produced by vascular endothelial cellsQ29620540
Paracrine mechanisms in adult stem cell signaling and therapyQ29620571
Strain and strain rate imaging by echocardiography - basic concepts and clinical applicabilityQ30481640
Lentiviral vectors bearing the cardiac promoter of the Na+-Ca2+ exchanger report cardiogenic differentiation in stem cellsQ30489102
Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemiaQ30492111
Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell deliveryQ33576955
Vascular responses to hypoxia and ischemiaQ33739281
Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice.Q35050037
Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutationsQ35693266
Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction.Q36282656
Regulation of gene expression by HIF-1.Q36474004
Cardiac dyssynchrony analysis using circumferential versus longitudinal strain: implications for assessing cardiac resynchronizationQ36676295
Adenoviral transfer of HIF-1alpha enhances vascular responses to critical limb ischemia in diabetic miceQ37413615
Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodellingQ37694105
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.Q38315198
Generation of an epigenetic signature by chronic hypoxia in prostate cellsQ39827986
Timing of intracoronary bone-marrow-derived stem cell transplantation after ST-elevation myocardial infarctionQ40348049
Early expression of angiogenesis factors in acute myocardial ischemia and infarctionQ41722694
Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathwayQ42162154
Experimental validation of a new ultrasound method for the simultaneous assessment of radial and longitudinal myocardial deformation independent of insonation angleQ42669831
Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1.Q43491607
Myocardial contractility by strain echocardiography: comparison with physiological measurements in an in vitro modelQ44542226
Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes: novel basis for modulation of cardiac conduction by gene therapyQ45867972
Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemiaQ45871892
Major role for hypoxia inducible factor-1 and the endothelin system in promoting myocardial infarction and hypertension in an animal model of obstructive sleep apnea.Q46055084
Relation of tissue displacement and strain to invasively determined right ventricular stroke volumeQ46743757
Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarctionQ48919478
Direct intramyocardial but not intracoronary injection of bone marrow cells induces ventricular arrhythmias in a rat chronic ischemic heart failure model.Q50688973
Comparison between different speckle tracking and color tissue Doppler techniques to measure global and regional myocardial deformation in children.Q50697796
Endothelin System–Dependent Cardiac Remodeling in Renovascular HypertensionQ57570926
Hypoxia-Inducible Factor-1 (HIF-1)Q61645733
Regulation of vascularization by hypoxia-inducible factor 1Q64375116
Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemiaQ64378622
Role of cAMP and calcium influx in endothelin-1-induced ANP release in rat cardiomyocytesQ73890649
Role of endothelin and endothelin A-type receptor in adaptation of the carotid body to chronic hypoxiaQ74064982
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)363-372
P577publication date2011-05-03
P1433published inJournal of Cardiovascular Translational ResearchQ6294906
P1476titleConstitutive HIF-1α expression blunts the beneficial effects of cardiosphere-derived cell therapy in the heart by altering paracrine factor balance
P478volume4

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cites work (P2860)
Q48004345Engineered myocardium model to study the roles of HIF-1α and HIF1A-AS1 in paracrine-only signaling under pathological level oxidative stress
Q37165628Hyaluronic acid-serum hydrogels rapidly restore metabolism of encapsulated stem cells and promote engraftment.
Q37611026Metformin promotes the survival of transplanted cardiosphere-derived cells thereby enhancing their therapeutic effect against myocardial infarction
Q41052065Paracrine Engineering of Human Cardiac Stem Cells With Insulin-Like Growth Factor 1 Enhances Myocardial Repair
Q50872139Paracrine Engineering of Human Explant-Derived Cardiac Stem Cells to Over-Express Stromal-Cell Derived Factor 1α Enhances Myocardial Repair.
Q27012551Potential of cardiac stem/progenitor cells and induced pluripotent stem cells for cardiac repair in ischaemic heart disease
Q38577907Prolyl hydroxylase inhibitors act as agents to enhance the efficiency of cell therapy
Q37975993SPECT and PET to optimize cardiac stem cell therapy

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