Ischemia-reperfusion lung injury is attenuated in MyD88-deficient mice

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Ischemia-reperfusion lung injury is attenuated in MyD88-deficient mice is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...877123A
P356DOI10.1371/JOURNAL.PONE.0077123
P932PMC publication ID3795647
P698PubMed publication ID24146959
P5875ResearchGate publication ID258066522

P50authorWilliam A. AltemeierQ51141705
W Conrad LilesQ89016908
P2093author name stringRobb W Glenny
Gustavo Matute-Bello
Ana Villagra-Garcia
P2860cites workScience review: redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1alphaQ24794593
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathwaysQ29616209
Reperfusion injury significantly impacts clinical outcome after pulmonary transplantationQ30305840
Attenuation of lung reperfusion injury after transplantation using an inhibitor of nuclear factor-kappaB.Q30305998
Ischemia-reperfusion injury after lung transplantation increases risk of late bronchiolitis obliterans syndromeQ30309305
Toll-like receptor 4 modulates myocardial ischaemia-reperfusion injury: Role of matrix metalloproteinasesQ33249383
Plasma cytokines and chemokines in primary graft dysfunction post-lung transplantationQ33653089
Regulation of interleukin-8 gene expressionQ33674279
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidneyQ33948196
Regulation of lung injury and repair by Toll-like receptors and hyaluronanQ34462186
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathwaysQ34625047
A universal role for MyD88 in TLR/IL-1R-mediated signalingQ34825992
MyD88 as a bottle neck in Toll/IL-1 signalingQ35017555
Ischemia-reperfusion-induced lung injury.Q35067234
TLR2 ligand induces protection against cerebral ischemia/reperfusion injury via activation of phosphoinositide 3-kinase/Akt signalingQ35118932
Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in miceQ35541859
Endogenous ligands of Toll-like receptorsQ35792678
TLR4 activation mediates kidney ischemia/reperfusion injuryQ35987574
The role of postischemic reperfusion injury and other nonantigen-dependent inflammatory pathways in transplantation.Q36064737
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusionQ36403403
Plasma monocyte chemotactic protein-1 levels at 24 hours are a biomarker of primary graft dysfunction after lung transplantation.Q36405808
Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage.Q36626556
Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptorsQ36726933
Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunityQ36990647
Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edemaQ37264724
Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injuryQ38278784
Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.Q40541858
Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed miceQ42575229
A small molecule inhibitor of redox-regulated NF-kappa B and activator protein-1 transcription blocks allergic airway inflammation in a mouse asthma modelQ44187685
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injuryQ44231448
Critical role of reactive nitrogen species in lung ischemia-reperfusion injuryQ44520629
Inhibition of c-Jun NH2-terminal kinase activity improves ischemia/reperfusion injury in rat lungs.Q44757041
Toll-like receptor 4 involvement in hepatic ischemia/reperfusion injury in miceQ44892354
CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury.Q46033796
Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient miceQ47200145
The Toll-like receptor 9 ligand CPG-C attenuates acute inflammatory cardiac dysfunctionQ48884290
Optimal timing to repopulation of resident alveolar macrophages with donor cells following total body irradiation and bone marrow transplantation in mice.Q50793664
Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells.Q54630390
Pattern of injury and the role of neutrophils in reperfusion injury of rat lungQ72335918
Interleukin-8 release during early reperfusion predicts graft function in human lung transplantationQ77487113
Toll-like receptor 4 mediates lung ischemia-reperfusion injuryQ79381830
Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injuryQ79839081
Protection against myocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinositide 3-kinase-dependent mechanismQ80358575
Toll-like receptor 4 mediates ischemia/reperfusion injury of the heartQ80392200
Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injuryQ82282486
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibodyQ82307930
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectpulmonary injuryQ7259546
P304page(s)e77123
P577publication date2013-10-11
P1433published inPLOS OneQ564954
P1476titleIschemia-reperfusion lung injury is attenuated in MyD88-deficient mice
P478volume8