Differential effects of inescapable stress on locus coeruleus GRK3, alpha2-adrenoceptor and CRF1 receptor levels in learned helpless and non-helpless rats: a potential link to stress resilience

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Differential effects of inescapable stress on locus coeruleus GRK3, alpha2-adrenoceptor and CRF1 receptor levels in learned helpless and non-helpless rats: a potential link to stress resilience is …
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scholarly articleQ13442814

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P356DOI10.1016/J.BBR.2011.02.018
P932PMC publication ID3108052
P698PubMed publication ID21333691
P5875ResearchGate publication ID49847959

P2093author name stringSamina Salim
David B Bylund
Douglas C Eikenburg
Frederick Petty
H Kevin Happe
Kaustuv Saha
Manish Taneja
Nidal Qutna
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Role of 90-kDa heat shock protein (Hsp 90) and protein degradation in regulating neuronal levels of G protein-coupled receptor kinase 3.Q40192474
Cellular G protein-coupled receptor kinase levels regulate sensitivity of the {alpha}2b-adrenergic receptor to undergo agonist-induced down-regulationQ40509352
GRK3 mediates desensitization of CRF1 receptors: a potential mechanism regulating stress adaptationQ40821076
Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleusQ41223243
Rapid agonist-induced phosphorylation of the human CRF receptor, type 1: a potential mechanism for homologous desensitizationQ41719969
Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons.Q42439467
Moderate treadmill exercise prevents oxidative stress-induced anxiety-like behavior in ratsQ43197565
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Treatment with escitalopram but not desipramine decreases escape latency times in a learned helplessness model using juvenile rats.Q46039997
Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutationQ46134806
Effect of number of tailshocks on learned helplessness and activation of serotonergic and noradrenergic neurons in the rat.Q46507484
Somatodendritic alpha2-adrenoceptors in the locus coeruleus are involved in the in vivo modulation of cortical noradrenaline release by the antidepressant desipramineQ47777731
Relationship between locus coeruleus discharge rates and rates of norepinephrine release within neocortex as assessed by in vivo microdialysisQ48103851
Learned helplessness sensitizes hippocampal norepinephrine to mild restressQ48105439
Activation of the CRF(1) receptor causes ERK1/2 mediated increase in GRK3 expression in CATH.a cellsQ48130021
Regulation of GRK 2 and 6, beta-arrestin-2 and associated proteins in the prefrontal cortex of drug-free and antidepressant drug-treated subjects with major depressionQ48356071
Reversal of behavioral depression by infusion of an alpha-2 adrenergic agonist into the locus coeruleusQ48362825
Depression in an animal model: focus on the locus ceruleusQ48414171
Prevention of learned helplessness: in vivo correlation with cortical serotoninQ48423721
Activation of the locus coeruleus noradrenergic system by intracoerulear microinfusion of corticotropin-releasing factor: effects on discharge rate, cortical norepinephrine levels and cortical electroencephalographic activityQ48749012
Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleusQ48777789
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Altered sensitivity to rewarding and aversive drugs in mice with inducible disruption of cAMP response element-binding protein function within the nucleus accumbensQ95801666
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)25-33
P577publication date2011-02-17
P1433published inBehavioural Brain ResearchQ3619047
P1476titleDifferential effects of inescapable stress on locus coeruleus GRK3, alpha2-adrenoceptor and CRF1 receptor levels in learned helpless and non-helpless rats: a potential link to stress resilience
P478volume221

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