MicroRNA-34a functions as an anti-metastatic microRNA and suppresses angiogenesis in bladder cancer by directly targeting CD44

scientific article

MicroRNA-34a functions as an anti-metastatic microRNA and suppresses angiogenesis in bladder cancer by directly targeting CD44 is …
instance of (P31):
scholarly articleQ13442814

External links are
P932PMC publication ID4311467
P698PubMed publication ID25551284
P5875ResearchGate publication ID270289596

P2093author name stringHeng Li
Hua Xu
Wei Xiao
Bin Lang
Gan Yu
Weimin Yao
P2860cites workThe microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44Q24617130
Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancerQ24644185
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cellsQ24657020
MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastomaQ27320938
The functions of animal microRNAsQ27860621
Origins and Mechanisms of miRNAs and siRNAsQ27860822
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Micro-RNA profiling in kidney and bladder cancersQ28247306
Causes and consequences of microRNA dysregulation in cancerQ28258994
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34Q28285980
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancerQ28291502
Cisplatin-induced epigenetic activation of miR-34a sensitizes bladder cancer cells to chemotherapyQ33615709
Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like charactersQ33809987
Non-invasive detection of bladder cancer by identification of abnormal CD44 proteins in exfoliated cancer cells in urineQ33837593
p53 regulates glucose metabolism by miR-34a.Q46913843
Immunohistochemical expression of CD44s in renal cell carcinoma lacks independent prognostic significance.Q51326636
Prognostic significance of CA 125, CD44, and epithelial membrane antigen in renal cell carcinomaQ57904997
Translating MicroRNA discovery into clinical biomarkers in cancerQ80249634
A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancerQ34071175
MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells.Q34107306
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.Q34130311
Axillary node metastasis from differentiated thyroid carcinoma with Hürthle and signet ring cell differentiation. A case of disseminated thyroid cancer with peculiar histologic findings.Q34150517
miR-143, miR-222, and miR-452 are useful as tumor stratification and noninvasive diagnostic biomarkers for bladder cancerQ34262050
Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: increased expression of a CD44 variant isoform after chemotherapyQ34432525
miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancerQ34544501
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progressionQ34627193
MicroRNA-320c inhibits tumorous behaviors of bladder cancer by targeting Cyclin-dependent kinase 6Q35605883
MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinomaQ35730683
Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancerQ35855955
Chromosome 4p16.3 variant modify bladder cancer risk in a Chinese populationQ35857520
Sequence variant on 8q24 confers susceptibility to urinary bladder cancerQ35964294
CD44+/CD24- phenotype contributes to malignant relapse following surgical resection and chemotherapy in patients with invasive ductal carcinomaQ36202984
CD44 is associated with tumor recurrence and is an independent poor prognostic factor for patients with localized clear cell renal cell carcinoma after nephrectomyQ36224896
Plasma specific miRNAs as predictive biomarkers for diagnosis and prognosis of gliomaQ36560956
Epidemiology of urinary bladder cancer: from tumor development to patient's deathQ36832297
A microRNA DNA methylation signature for human cancer metastasisQ36861111
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesisQ36893701
MicroRNAs as regulators of epithelial-mesenchymal transition.Q37300965
Recurrence and progression of disease in non-muscle-invasive bladder cancer: from epidemiology to treatment strategyQ37540810
Increased CD44s and decreased CD44v6 RNA expression are associated with better survival in myxofibrosarcoma patients: a pilot studyQ37616756
MicroRNAs in colorectal cancer: translation of molecular biology into clinical applicationQ37632608
MicroRNA in prostate, bladder, and kidney cancer: a systematic review.Q37836137
miRNA-34a suppresses cell proliferation and metastasis by targeting CD44 in human renal carcinoma cellsQ38991056
Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation.Q39044097
EpCAM expression in the prostate cancer makes the difference in the response to growth factorsQ39048151
MiR-34a targets GAS1 to promote cell proliferation and inhibit apoptosis in papillary thyroid carcinoma via PI3K/Akt/Bad pathwayQ39063949
Delta-tocotrienol suppresses Notch-1 pathway by upregulating miR-34a in nonsmall cell lung cancer cellsQ39375782
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancyQ39465507
MiR-34a chemosensitizes bladder cancer cells to cisplatin treatment regardless of p53-Rb pathway statusQ39518813
Circulating miR-34a levels are reduced in colorectal cancerQ39610241
Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver.Q44615667
P921main subjectmicroRNAQ310899
P304page(s)779
P577publication date2014-12-31
P1433published inJournal of Experimental & Clinical Cancer ResearchQ13739415
P1476titleMicroRNA-34a functions as an anti-metastatic microRNA and suppresses angiogenesis in bladder cancer by directly targeting CD44
P478volume33

Reverse relations

cites work (P2860)
Q64263672Anti-cancer Effects of a Chemically Modified miR-143 on Bladder Cancer by Either Systemic or Intravesical Treatment
Q58697956CD44/CD44v6 a Reliable Companion in Cancer-Initiating Cell Maintenance and Tumor Progression
Q63561064CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells
Q36529359Characteristics of Patients With Transitional Cell Carcinoma of the Urinary Bladder in Kermanshah Province, Iran
Q37210703Combined expression of miR-34a and Smac mediated by oncolytic vaccinia virus synergistically promote anti-tumor effects in Multiple Myeloma
Q39331536Current Concepts of Epigenetics in Testicular Cancer
Q33689126Dysregulation of miRNAs in bladder cancer: altered expression with aberrant biogenesis procedure
Q92072853Epigenetics of Bladder Cancer: Where Biomarkers and Therapeutic Targets Meet
Q35825993Hypoxia-inducible MiR-182 promotes angiogenesis by targeting RASA1 in hepatocellular carcinoma
Q26770381Interplay Between Metabolism and Oncogenic Process: Role of microRNAs
Q35869716Low expression of microRNA-204 (miR-204) is associated with poor clinical outcome of acute myeloid leukemia (AML) patients.
Q90079974MicroRNA Networks Modulate Oxidative Stress in Cancer
Q37699408MicroRNA-34a expression levels in serum and intratumoral tissue can predict bone metastasis in patients with hepatocellular carcinoma
Q90441365MicroRNA-34a suppresses breast cancer cell proliferation and invasion by targeting Notch1
Q50221158MicroRNA-34a suppresses invasion and metastatic in esophageal squamous cell carcinoma by regulating CD44.
Q43184280MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma
Q44463289MicroRNA-34a: A Versatile Regulator of Myriads of Targets in Different Cancers.
Q47703386MicroRNAs in cancer metastasis and angiogenesis
Q64093654Obatoclax, a BH3 Mimetic, Enhances Cisplatin-Induced Apoptosis and Decreases the Clonogenicity of Muscle Invasive Bladder Cancer Cells via Mechanisms That Involve the Inhibition of Pro-Survival Molecules as Well as Cell Cycle Regulators
Q35344075Signaling by exosomal microRNAs in cancer.
Q26741223The Significance of Epithelial-to-Mesenchymal Transition for Circulating Tumor Cells
Q26771509The role of CD44 in epithelial-mesenchymal transition and cancer development
Q26744149The role of microRNAs in bladder cancer
Q39432577Understanding the Role of Non-Coding RNAs in Bladder Cancer: From Dark Matter to Valuable Therapeutic Targets.
Q55126311Understanding the biology of urothelial cancer metastasis.
Q90381696c-Myc Acts as a Competing Endogenous RNA to Sponge miR-34a, in the Upregulation of CD44, in Urothelial Carcinoma
Q41646109miR-107 promotes hepatocellular carcinoma cell proliferation by targeting Axin2.
Q90046505miRNA-34a inhibits cell adhesion by targeting CD44 in human renal epithelial cells: implications for renal stone disease
Q38764391miRNA-34a promotes proliferation of human pulmonary artery smooth muscle cells by targeting PDGFRA.
Q89883646miRNAs: A Promising Target in the Chemoresistance of Bladder Cancer
Q39285150miRNAs: micro-managers of anticancer combination therapies.

Search more.