Genetic differences in drug metabolism associated with ocular toxicity

scientific article

Genetic differences in drug metabolism associated with ocular toxicity is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1289/EHP.8244107
P932PMC publication ID1568975
P698PubMed publication ID7044772

P2093author name stringNebert DW
Shichi H
P2860cites workThe Ah Locus and the Metabolism of Chemical Carcinogens and Other Foreign CompoundsQ28512468
Genetic differences in susceptibility to chemically induced myelotoxicity and leukemiaQ35035886
Multiple forms of inducible drug-metabolizing enzymes: A reasonable mechanism by which any organism can cope with adversityQ38039795
Possible reactions of 1,2-naphthaquinone in the eyeQ39264288
Pharmacogenetics: a possible pragmatic perspective in neoplasm predictabilityQ39719319
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Developmental Aspects of Drug Conjugation, with Special Reference to GlucuronidationQ39877389
Chloroquine ocular toxicityQ40013175
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Genetic mechanisms controlling the induction of polysubstrate monooxygenase (P-450) activitiesQ40306973
Metabolism of naphthalene to naphthalene dihydrodiol glucuronide in isolated hepatocytes and in liver microsomesQ41839891
Metabolism of polycyclic compounds. 18. The secretion of metabolites of naphthalene, 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene in rat bileQ42963584
Experimental studies on cataractQ43734439
Genetic factors related to glaucomaQ44951676
Ah Locus: Genetic Differences in Susceptibility to Cataracts Induced by AcetaminophenQ45148356
Conversion of naphthalene to trans-naphthalene dihydrodiol: Evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomesQ54037046
Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocationQ66961535
Acetaminophen overdoses at a county hospital: a year's experienceQ67411938
Aryl hydrocarbon hydroxylase induction in retinal pigmented epithelium: possible association of genetic differences in a drug-metabolizing enzyme system with retinal degenerationQ67833284
Microsomal electron transfer system of bovine retinal pigment epitheliumQ68733136
Localization of gamma-glutamyl transpeptidase in rabbit lens, ciliary process and corneaQ70043959
Regulatory gene product of the Ah complex. Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene binding to several moieties in mouse liver cytosolQ70730064
Purification and properties of bovine lens glutathione S-transferaseQ71157954
Genetic differences in cataract and other ocular abnormalities induced by paracetamol and naphthaleneQ71250212
1,2-Naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. VQ71409096
Enzymes of mercapturate synthesis and other drug-metabolizing reactions-specific localization in the eyeQ72515312
Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in continuous cell culture linesQ72872400
P921main subjecteye diseaseQ3041498
pharmaceutical preparationQ66089252
P1104number of pages11
P304page(s)107-117
P577publication date1982-04-01
P1433published inEnvironmental Health PerspectivesQ1345904
P1476titleGenetic differences in drug metabolism associated with ocular toxicity
P478volume44

Reverse relations

cites work (P2860)
Q39367508Aryl hydrocarbon receptor (AHR): "pioneer member" of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family of "sensors" of foreign and endogenous signals
Q46544139Cytochrome P450 Activity in Ex Vivo Cornea Models and a Human Cornea Construct
Q72314373Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues
Q44204455Immunocytochemical study of phenobarbital- and 3-methylcholanthrene-inducible cytochrome P450 isozymes in primary cultures of porcine ciliary epithelium
Q26851574Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition
Q39259079Ocular non-P450 oxidative, reductive, hydrolytic, and conjugative drug metabolizing enzymes
Q38092131Pharmacogenetics of drugs used in the treatment of ocular inflammatory diseases
Q36939218Phase I and phase II ocular metabolic activities and the role of metabolism in ophthalmic prodrug and codrug design and delivery.
Q42854132Purification and properties of anionic glutathione S-transferase from bovine ciliary body
Q36089991Strain differences in mice in carbon tetrachloride-induced liver injury
Q40200366The melanin binding of drugs and its implications

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