Lactate-modulated induction of THBS-1 activates transforming growth factor (TGF)-beta2 and migration of glioma cells in vitro

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Lactate-modulated induction of THBS-1 activates transforming growth factor (TGF)-beta2 and migration of glioma cells in vitro is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...878935S
P356DOI10.1371/JOURNAL.PONE.0078935
P932PMC publication ID3815307
P698PubMed publication ID24223867
P5875ResearchGate publication ID258504967

P50authorUlrich BogdahnQ50637667
Peter HauQ50637784
Arabel Vollmann-ZwerenzQ50637810
Martin ProescholdtQ50637862
Alexander BrawanskiQ50638383
P2093author name stringAnja-Katrin Bosserhoff
Marina Kreutz
Petra Leukel
Sylvia Moeckel
Corinna Seliger
Claudio Lottaz
Birgit Jachnik
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CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profilesQ48177168
Mapping of brain tumor metabolites with proton MR spectroscopic imaging: clinical relevanceQ48401235
Correlation of endothelin-1 and transforming growth factor beta 1 with malignancy and vascularity in human gliomas.Q48749534
Participation of thrombospondin-1 in the activation of latent transforming growth factor-beta in malignant glioma cellsQ48853907
Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2.Q55474355
Expression of TGF-beta isoforms, TGF-beta receptors, and SMAD molecules at different stages of human glioma.Q55475527
Cyclic AMP regulation of lactate dehydrogenase. Isoproterenol and N6,O2'-dibutyryl cyclic AMP increase the levels of lactate dehydrogenase-5 isozyme and its messenger RNA in rat C6 glioma cellsQ55490653
The thrombospondinsQ57919794
Metabolic consequences of a reversed pH gradient in rat tumorsQ60536733
Quantitating tumor glucose metabolism with FDG and PETQ67755352
Thrombospondin-1 induces matrix metalloproteinase-2 activation in vascular smooth muscle cellsQ73618847
The activation sequence of thrombospondin-1 interacts with the latency-associated peptide to regulate activation of latent transforming growth factor-betaQ77388281
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude miceQ79834386
Cellular response to hypoxia involves signaling via Smad proteinsQ24314797
Direct binding of occupied urokinase receptor (uPAR) to LDL receptor-related protein is required for endocytosis of uPAR and regulation of cell surface urokinase activityQ24633333
Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1Q24672489
On the Origin of Cancer CellsQ27861025
Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiologyQ28138090
Making sense of latent TGFbeta activationQ28217641
On respiratory impairment in cancer cellsQ29617276
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in miceQ30080001
Expression of thrombospondin-1 in human hepatocarcinoma cell lines and its regulation by transcription factor Jun/AP-1.Q32054616
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.Q33387162
TNF-alpha induces TGF-beta1 expression in lung fibroblasts at the transcriptional level via AP-1 activationQ33793939
Thrombospondins: multifunctional regulators of cell interactionsQ34425129
Targeted tumor therapy with the TGF-beta 2 antisense compound AP 12009.Q34479492
The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteinsQ35059796
Lactate: mirror and motor of tumor malignancyQ35837050
Transforming growth factor-beta: a molecular target for the future therapy of glioblastomaQ36384944
Cancer stem cells and gliomaQ37217237
Antisense-mediated reduction in thrombospondin-1 expression reduces cell motility in malignant glioma cellsQ38293865
Human ovarian cancer cell morphology, motility, and proliferation are differentially influenced by autocrine TGFβ superfamily signalling.Q39468567
1H-nuclear magnetic resonance spectroscopy of glioblastoma cancer stem cellsQ39603128
Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studiesQ40105658
An imbalance between Smad and MAPK pathways is responsible for TGF-beta tumor promoting effects in high-grade gliomasQ40186847
RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.Q40474790
Lactate-sensitive response elements in genes involved in hyaluronan catabolismQ40649836
Correlation of thrombospondin-1 and transforming growth factor-beta expression with malignancy of gliomaQ40835307
TGF-beta autocrine loop regulates cell growth and myogenic differentiation in human rhabdomyosarcoma cells.Q40876493
The role of thrombospondin-1 in tumor progression and angiogenesisQ40964893
Regulation of tumor growth and metastasis by thrombospondin-1.Q41073499
Regulation of transforming growth factor-beta activation by discrete sequences of thrombospondin 1.Q41357814
The role of versican isoforms V0/V1 in glioma migration mediated by transforming growth factor-beta2.Q41870574
Are cancer cells acidic?Q42372356
Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell metabolismQ43624115
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)e78935
P577publication date2013-11-01
P1433published inPLOS OneQ564954
P1476titleLactate-modulated induction of THBS-1 activates transforming growth factor (TGF)-beta2 and migration of glioma cells in vitro
P478volume8

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cites work (P2860)
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