| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Frederick W Alt | |
| Thomas Perlot | |||
| P2860 | cites work | Translating the Histone Code | Q22065840 |
| Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals | Q22122053 | ||
| RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination | Q27649126 | ||
| The RAG proteins and V(D)J recombination: complexes, ends, and transposition | Q28145648 | ||
| Recent advances in understanding chromatin remodeling by Swi/Snf complexes | Q28188333 | ||
| Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi | Q28218870 | ||
| Developmentally controlled and tissue-specific expression of unrearranged VH gene segments | Q28259020 | ||
| The lingering enigma of the allelic exclusion mechanism | Q28279891 | ||
| Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase | Q28298958 | ||
| B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5 | Q28505973 | ||
| Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins | Q29614507 | ||
| Genome-wide map of nucleosome acetylation and methylation in yeast | Q29614525 | ||
| The immunoglobulin IGHD gene locus in C57BL/6 mice | Q31107178 | ||
| Shutdown of class switch recombination by deletion of a switch region control element. | Q41573717 | ||
| Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line | Q41672433 | ||
| The immunoglobulin heavy-chain enhancer functions as the promoter for I mu sterile transcription | Q41733130 | ||
| Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase | Q41760941 | ||
| Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells | Q41834813 | ||
| Transcription of productive and nonproductive VDJ-recombined alleles after IgH allelic exclusion | Q41944163 | ||
| Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene | Q41945079 | ||
| Allelic exclusion in transgenic mice carrying mutant human IgM genes | Q42071866 | ||
| B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames | Q42627426 | ||
| Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region | Q42798746 | ||
| Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expressing B cells in mice. | Q42799157 | ||
| Family-specific differences in transcription efficiency of Ig heavy chain promoters | Q42799347 | ||
| Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage | Q42808536 | ||
| Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line | Q43720366 | ||
| Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion. | Q44410226 | ||
| C mu-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5'-nontranslatable exon | Q44747778 | ||
| Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation | Q46053556 | ||
| Transcriptional repression mediated by repositioning of genes to the nuclear lamina | Q46755262 | ||
| Perinuclear localization of chromatin facilitates transcriptional silencing | Q47675987 | ||
| Antisense intergenic transcription in V(D)J recombination | Q47703435 | ||
| Somatic hypermutation in the heavy chain locus correlates with transcription | Q47713194 | ||
| Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus | Q47788471 | ||
| Regulation of immunoglobulin light chain isotype expression | Q47911157 | ||
| The mouse IgH 3'-enhancer | Q48223460 | ||
| Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines | Q48386738 | ||
| A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes | Q48397666 | ||
| A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene | Q48397674 | ||
| Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes. | Q48409957 | ||
| Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes. | Q48412817 | ||
| An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. | Q48413837 | ||
| Deregulated PAX-5 transcription from a translocated IgH promoter in marginal zone lymphoma. | Q50755728 | ||
| Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. | Q51840167 | ||
| Progressive activation of DNA replication initiation in large domains of the immunoglobulin heavy chain locus during B cell development. | Q52033311 | ||
| V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer | Q40873078 | ||
| A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon | Q40873846 | ||
| Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule. | Q40874673 | ||
| Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus. | Q40875075 | ||
| Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells | Q40974584 | ||
| Clonal selection and learning in the antibody system | Q41002744 | ||
| Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro | Q41191663 | ||
| Down-regulation of RAG1 and RAG2 gene expression in PreB cells after functional immunoglobulin heavy chain rearrangement | Q41278530 | ||
| Activation of V kappa gene rearrangement in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains | Q41352929 | ||
| A second promoter and enhancer element within the immunoglobulin heavy chain locus. | Q41475681 | ||
| CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication | Q41514689 | ||
| Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. | Q52110894 | ||
| Truncated immunoglobulin Dmu causes incomplete developmental progression of RAG-deficient pro-B cells. | Q52126352 | ||
| Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus. | Q52196159 | ||
| Persistent expression of an unproductive immunoglobulin heavy chain allele with DH-JH-gamma configuration in peripheral tissues. | Q54551860 | ||
| Deletion of germline promoter PD beta 1 from the TCR beta locus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms. | Q54584150 | ||
| A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus | Q56838225 | ||
| Rearrangement of IgH genes in normal thymocyte development | Q56922424 | ||
| Surrogate Light Chain Expression Is Required to Establish Immunoglobulin Heavy Chain Allelic Exclusion during Early B Cell Development | Q57198364 | ||
| Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion | Q59065258 | ||
| Asynchronous replication and allelic exclusion in the immune system | Q59095417 | ||
| Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells | Q59098599 | ||
| A class switch control region at the 3′ end of the immunoglobulin heavy chain locus | Q59886033 | ||
| Translocated c-myc genes produce chimeric transcripts containing antisense sequences of the immunoglobulin heavy chain locus in mouse plasmacytomas | Q69028194 | ||
| The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance | Q69874167 | ||
| Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence | Q69942457 | ||
| Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain | Q71514770 | ||
| Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA | Q73270505 | ||
| The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation | Q73316142 | ||
| Deletion of the DQ52 element within the Ig heavy chain locus leads to a selective reduction in VDJ recombination and altered D gene usage | Q73401098 | ||
| Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination | Q74419737 | ||
| Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter | Q77328514 | ||
| Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes | Q80521805 | ||
| Repeat organization and epigenetic regulation of the DH-Cmu domain of the immunoglobulin heavy-chain gene locus | Q81096346 | ||
| Regulation of IgH gene assembly: role of the intronic enhancer and 5'DQ52 region in targeting DHJH recombination | Q82459169 | ||
| Activation of V(D)J recombination at the IgH chain JH locus occurs within a 6-kilobase chromatin domain and is associated with nucleosomal remodeling | Q83170063 | ||
| Two antisense promoters in the immunoglobulin mu-switch region drive expression of c-myc in the Burkitt's lymphoma cell line BL67. | Q33224591 | ||
| Molecular processes that regulate class switching | Q33758685 | ||
| Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites | Q33823918 | ||
| Sites that direct nuclear compartmentalization are near the 5' end of the mouse immunoglobulin heavy-chain locus | Q33884101 | ||
| The 3' IgH regulatory region: a complex structure in a search for a function | Q33957718 | ||
| Elucidation of IgH intronic enhancer functions via germ-line deletion | Q34063681 | ||
| Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development | Q34122320 | ||
| Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility | Q34155960 | ||
| Factors and forces controlling V(D)J recombination | Q34296487 | ||
| Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter | Q34359857 | ||
| Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin | Q34450725 | ||
| Mechanism and control of class-switch recombination | Q34500935 | ||
| Gene segment selection in V(D)J recombination: accessibility and beyond | Q34534913 | ||
| Accessibility control of V(D)J recombination | Q34570422 | ||
| Nuclear organisation and gene expression | Q34688480 | ||
| Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development | Q34784427 | ||
| Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions | Q34997657 | ||
| Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus | Q35064395 | ||
| Kappa chain monoallelic demethylation and the establishment of allelic exclusion | Q35202527 | ||
| Chromatin remodeling directly activates V(D)J recombination | Q35631962 | ||
| Transcriptional control of early B cell development | Q35698401 | ||
| The role of the non-homologous end-joining pathway in lymphocyte development | Q35830410 | ||
| Monoallelic gene expression: a repertoire of recurrent themes | Q35830431 | ||
| An enhancer at the 3' end of the mouse immunoglobulin heavy chain locus | Q35914587 | ||
| Antisense intergenic transcription precedes Igh D-to-J recombination and is controlled by the intronic enhancer Emu. | Q35950042 | ||
| Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments | Q35963602 | ||
| Immunoglobulin locus silencing and allelic exclusion | Q36057588 | ||
| Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences | Q36097515 | ||
| Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4 | Q36161311 | ||
| The beyond 12/23 restriction is imposed at the nicking and pairing steps of DNA cleavage during V(D)J recombination | Q36177454 | ||
| Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci | Q36228744 | ||
| Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription | Q36230026 | ||
| Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow | Q36230070 | ||
| Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence | Q36258756 | ||
| Expression of a cloned adenovirus gene is inhibited by in vitro methylation | Q36281826 | ||
| Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination | Q36294406 | ||
| In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells | Q36297565 | ||
| Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice | Q36350730 | ||
| Developmentally regulated and strain-specific expression of murine VH gene families | Q36355024 | ||
| Insertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangement | Q36369258 | ||
| B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors | Q36399230 | ||
| Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers. | Q36404262 | ||
| Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus | Q36427367 | ||
| Genetic and epigenetic regulation of IgH gene assembly | Q36449969 | ||
| Antisense transcripts from immunoglobulin heavy-chain locus V(D)J and switch regions | Q36499177 | ||
| Ordered rearrangement of immunoglobulin heavy chain variable region segments | Q36586574 | ||
| The immunoglobulin heavy chain locus contains another B-cell-specific 3' enhancer close to the alpha constant region | Q36675781 | ||
| Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation | Q36688566 | ||
| The pre-B-cell receptor. | Q36738390 | ||
| Molecular mechanisms of antibody somatic hypermutation. | Q36747477 | ||
| Structure and expression of germ line immunoglobulin gamma 2b transcripts | Q36787710 | ||
| Evolution of the immunoglobulin heavy chain class switch recombination mechanism | Q36845675 | ||
| A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement | Q37013832 | ||
| S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase | Q37164427 | ||
| V(D)J recombination is not activated by demethylation of the kappa locus | Q37229219 | ||
| Sequence and characterization of the Ig heavy chain constant and partial variable region of the mouse strain 129S1. | Q37407401 | ||
| The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions. | Q37407403 | ||
| Methylation patterns of immunoglobulin genes in lymphoid cells: correlation of expression and differentiation with undermethylation | Q37549599 | ||
| Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5. | Q38323522 | ||
| Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter | Q38346589 | ||
| Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement | Q38359938 | ||
| Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene | Q38398480 | ||
| Evidence that immunoglobulin VH-DJ recombination does not require germ line transcription of the recombining variable gene segment | Q39576391 | ||
| Stepwise activation of the immunoglobulin mu heavy chain gene locus | Q39646140 | ||
| Identification of a candidate regulatory element within the 5' flanking region of the mouse Igh locus defined by pro-B cell-specific hypersensitivity associated with binding of PU.1, Pax5, and E2A. | Q40278119 | ||
| Regulation of TCRbeta gene assembly by a promoter/enhancer holocomplex | Q40291803 | ||
| Targeted inhibition of V(D)J recombination by a histone methyltransferase | Q40585376 | ||
| Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements | Q40669450 | ||
| B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements | Q40684775 | ||
| The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development | Q40689893 | ||
| Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes. | Q40783286 | ||
| Chromatin remodeling at the Ig loci prior to V(D)J recombination | Q40794209 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cis-regulatory element | Q1093165 |
| P304 | page(s) | 1-32 | |
| P577 | publication date | 2008-01-01 | |
| P1433 | published in | Advances in Immunology | Q15752932 |
| P1476 | title | Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus | |
| P478 | volume | 99 |
| Q42034225 | 4C-ing the Igh Landscape |
| Q37164471 | AID hits the jackpot when missing the target |
| Q27692655 | AID targeting is dependent on RNA polymerase II pausing |
| Q42545276 | Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells. |
| Q96430927 | An Erg-driven transcriptional program controls B cell lymphopoiesis |
| Q33749938 | Analysis of mice lacking DNaseI hypersensitive sites at the 5' end of the IgH locus |
| Q38581000 | BTK Signaling in B Cell Differentiation and Autoimmunity |
| Q35090055 | CTCF-binding elements 1 and 2 in the Igh intergenic control region cooperatively regulate V(D)J recombination |
| Q42145363 | CTCF-binding elements mediate control of V(D)J recombination |
| Q37862986 | Design principles of adaptive immune systems |
| Q40510522 | Epigenetic Regulation in Amyloid Precursor Protein with Genomic Rearrangements and the Lesch-Nyhan Syndrome |
| Q33653705 | Epigenetic control of immunity |
| Q48147712 | Epigenetic modifications of the VH region after DJH recombination in Pro-B cells |
| Q34167461 | Epigenetic regulation of antigen receptor gene rearrangement |
| Q26772330 | Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response |
| Q39606893 | Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire |
| Q37417907 | Genomic Architecture may Influence Recurrent Chromosomal Translocation Frequency in the Igh Locus |
| Q24628758 | Histone H3K27ac separates active from poised enhancers and predicts developmental state |
| Q36534234 | Immunoglobulin class-switch DNA recombination: induction, targeting and beyond |
| Q36936198 | Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctions |
| Q93052882 | Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia |
| Q38267342 | Old questions, new tools: does next-generation sequencing hold the key to unraveling intestinal B-cell responses? |
| Q35099409 | Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions |
| Q37260841 | Role of the Igh intronic enhancer Eμ in clonal selection at the pre-B to immature B cell transition |
| Q38438140 | Seeking sense of antisense switch transcripts. |
| Q36598995 | Sequential activation and distinct functions for distal and proximal modules within the IgH 3' regulatory region |
| Q42734844 | Targeted chromatin profiling reveals novel enhancers in Ig H and Ig L chain Loci. |
| Q57191210 | The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination |
| Q37809817 | The IgH 3' regulatory region and its implication in lymphomagenesis. |
| Q26852963 | The Interplay between Chromatin and Transcription Factor Networks during B Cell Development: Who Pulls the Trigger First? |
| Q43058065 | The contraction of time and space in remote chromosomal interactions |
| Q36235676 | Three-dimensional architecture of the IgH locus facilitates class switch recombination |
| Q36936186 | Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus |
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