Prevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031.

scientific article

Prevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.BJP.0706054
P932PMC publication ID1575983
P698PubMed publication ID15644877
P5875ResearchGate publication ID8086312

P2093author name stringAkira Kagayama
Yoichi Naritomi
Yoshimasa Imamura
Takeshi Ishikawa
Seitaro Mutoh
Yoshitaka Ohkubo
Fusako Nishigaki
Yoshitaka Hirayama
Susumu Miyata
Kyoko Minoura
Masahiro Neya
Junko Imanishi
Tsuyoshi Mizutani
Hidetsugu Murai
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Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloproteaseQ28618841
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Matrix metalloproteinases and venous leg ulcerationQ33868197
Expression and regulation of aggrecanase in arthritis: the role of TGF-betaQ34110312
VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritisQ34217504
Selective matrix metalloproteinase (MMP) inhibition in rheumatoid arthritis--targetting gelatinase A activationQ34273821
How do the biologics fit into the current DMARD armamentarium?Q34284422
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Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark?Q34510718
Matrix metalloproteinase inhibitors in rheumatic diseasesQ34560579
Immunohistochemical detection and immunochemical analysis of type II collagen degradation in human normal, rheumatoid, and osteoarthritic articular cartilages and in explants of bovine articular cartilage cultured with interleukin 1Q34566923
Ro 32-3555, an orally active collagenase inhibitor, prevents cartilage breakdown in vitro and in vivoQ35026212
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Matrix metalloproteinases A review of their structure and role in acute coronary syndromeQ35557333
Infections and anti–tumor necrosis factor α therapyQ35581950
MT1-MMP: a tethered collagenaseQ35770291
Role of matrix metalloproteinases in failure to re-epithelialize after corneal injuryQ35782239
An immunoelectron microscope study of the organization of proteoglycan monomer, link protein, and collagen in the matrix of articular cartilageQ36206142
Autoimmunity to type II collagen an experimental model of arthritisQ36335891
IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosionQ37202023
Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independentQ37361470
Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid jointsQ37369629
Collagen arthritis as a relevant model for rheumatoid arthritisQ40338367
Using inhibitors of metalloproteinases to treat arthritis. Easier said than done?Q40684838
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromoleculesQ41133261
Suppression of adjuvant arthritis of rats by a novel matrix metalloproteinase-inhibitorQ43264390
Comparison of collagenase-cleaved articular cartilage collagen in mice in the naturally occurring STR/ort model of osteoarthritis and in collagen-induced arthritisQ43898917
Collagen-induced arthritis in rats. Evaluation of early immunologic eventsQ44196191
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Aggrecan protects cartilage collagen from proteolytic cleavageQ47724408
Collagen-induced arthritis in rhesus monkeys: evaluation of markers for inflammation and joint degradation.Q54140227
Immunisation against heterologous type II collagen induces arthritis in miceQ59053172
Joint destruction in arthritis: metalloproteinases in the spotlightQ68028254
Tissue distribution and clearance of soluble murine TNF receptors in miceQ72639124
Susceptibility of stromelysin 1-deficient mice to collagen-induced arthritis and cartilage destructionQ74060223
Reduced angiogenesis and tumor progression in gelatinase A-deficient miceQ74309789
Aggrecanase and metalloproteinase-specific aggrecan neo-epitopes are induced in the articular cartilage of mice with collagen II-induced arthritisQ74425441
Prevention of cartilage breakdown by matrix metalloproteinase inhibition--a realistic therapeutic target?Q74628449
Ro 32-3555, an orally active collagenase selective inhibitor, prevents structural damage in the STR/ORT mouse model of osteoarthritisQ77341396
Complex role of matrix metalloproteinases in angiogenesisQ77474882
Kinetics of aggrecanase- and metalloproteinase-induced neoepitopes in various stages of cartilage destruction in murine arthritisQ77872978
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)133-143
P577publication date2005-01-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titlePrevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031.
P478volume144

Reverse relations

cites work (P2860)
Q35907768A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release
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Q89964334Destroy to Rebuild: The Connection Between Bone Tissue Remodeling and Matrix Metalloproteinases
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Q33269680Type II collagen without adjuvant induces eosinophilic arthritis

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