Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro.

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Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.BJP.0706222
P932PMC publication ID1576187
P698PubMed publication ID15852038
P5875ResearchGate publication ID7885941

P50authorJuliano FerreiraQ108799462
Rodrigo MedeirosQ38360409
Maria Martha CamposQ42710301
Joao Batista CalixtoQ57011131
P2093author name stringValfredo Schlemper
P2860cites workPlacentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cellsQ24681236
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Involvement of cyclooxygenase 2 (COX-2) in intrinsic tone of isolated guinea pig tracheaQ30425026
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Enhanced relaxation of porcine coronary arteries after acute exposure to a physiological level of 17beta-estradiol involves non-genomic mechanisms and the cyclic AMP cascade.Q35042165
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Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea-pig isolated tracheaQ35874290
Pharmacological evaluation of a guinea-pig tracheal epithelium-derived inhibitory factor (EpDIF)Q35888453
The B1 receptors for kininsQ77355740
Inhibition of nuclear factor-kappaB prevents the loss of vascular tone in lipopolysaccharide-treated ratsQ78166820
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Inflammatory mediators and asthmaQ39556036
Pharmacology of bradykinin and related kinins.Q40306313
Potassium channels in airway smooth muscle: a tale of two channelsQ40713409
Mechanisms of prostaglandin E2 release by intact cells expressing cyclooxygenase-2: evidence for a 'two-component' model.Q40971687
Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assaysQ41079775
Differential role of extra- and intracellular calcium in bradykinin and interleukin 1 alpha stimulation of arachidonic acid release from A549 cellsQ41479983
Bradykinin stimulates cAMP synthesis via mitogen-activated protein kinase-dependent regulation of cytosolic phospholipase A2 and prostaglandin E2 release in airway smooth muscleQ41874156
Airway epithelium: more than just a barrier!Q42461353
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Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Role of the epitheliumQ43786845
Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell linesQ43945231
Mechanisms underlying the contraction induced by bradykinin in the guinea pig epithelium-denuded trachea.Q44003411
Bradykinin B2 receptor activates extracellular signal-regulated protein kinase in mIMCD-3 cells via epidermal growth factor receptor transactivationQ44327350
Hypoxia enhances a cGMP-independent nitric oxide relaxing mechanism in pulmonary arteriesQ44401132
Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomainsQ44664081
Nitric oxide relaxes rat tail artery smooth muscle by cyclic GMP-independent decrease in calcium sensitivity of myofilaments.Q44933767
Comparative airway response to inhaled bradykinin, kallidin, and [des-Arg9]bradykinin in normal and asthmatic subjectsQ45115466
Endogenous nitric oxide inhibits bronchoconstriction induced by cold-air inhalation in guinea pigs: role of kininsQ46226417
Bradykinin effects in guinea pig tracheal epithelial cells are mediated through a B2 kinin receptor and can be inhibited by the selective antagonist Hoe 140.Q46351330
Contribution of nitric oxide, prostanoids and Ca(2+)-activated K+ channels to the relaxant response of bradykinin in the guinea pig bronchus in vitroQ46394726
Potassium channel modulation: a new drug principle for regulation of smooth muscle contractility. Studies on isolated airways and arteriesQ46395207
Bradykinin-induced bronchoconstriction in guinea pig in vivo: role of neural mechanismsQ46772143
Effect of a bradykinin B2 antagonist on responses of intact and rubbed guinea-pig trachea in vitroQ46777309
Do perfused small caliber airways of guinea-pig release an epithelium-dependent relaxing factor?Q46818519
Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxideQ46873398
Evidence that Cultured Airway Smooth Muscle Cells Contain Bradykinin B2 and B3 ReceptorsQ53862630
Hyperpolarization as a mechanism for endothelium-dependent relaxations in the porcine coronary artery.Q54279661
Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificityQ59072840
Characterisation of the prostanoid receptors mediating contraction of guinea-pig isolated tracheaQ70087669
Pharmacological modulation of bradykinin-, acetylcholine- and calcium ionophore A23187-induced relaxation of rabbit pulmonary arterial segmentsQ70349040
Multiple mechanisms of bradykinin-induced contraction in rat and guinea pig smooth muscles in vitroQ70788136
Arachidonic acid metabolites and glucocorticoid regulatory mechanism in cultured porcine tracheal smooth muscle cellsQ70811357
Mechanisms involved in the relaxant response of bradykinin in epithelium intact strips of the guinea-pig tracheaQ71583404
6-Isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonistQ71598904
Pharmacology and mode of action of bradykinin on mouse-isolated tracheaQ73521202
NO(+) but not NO radical relaxes airway smooth muscle via cGMP-independent release of internal Ca(2+)Q73712481
PGE2 release by bradykinin in human airway smooth muscle cells: involvement of cyclooxygenase-2 inductionQ74065532
Prostanoid receptor heterogeneity through alternative mRNA splicingQ74539321
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)740-750
P577publication date2005-07-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleMechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro
P478volume145

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cites work (P2860)
Q38074605Airway epithelium-derived relaxing factor: myth, reality, or naivety?
Q41979441Interaction of prostanoid EP3 and TP receptors in guinea‐pig isolated aorta: contractile self‐synergism of 11‐deoxy‐16,16‐dimethyl PGE2
Q41584404Intraplantar PGE2 causes nociceptive behaviour and mechanical allodynia: the role of prostanoid E receptors and protein kinases
Q57784521Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite induced murine asthma model
Q48021730Neuronal and non-neuronal bradykinin receptors are involved in the contraction and/or relaxation to the pig bladder neck smooth muscle.
Q43220596Prostaglandins of the E series inhibit monoamine release via EP3 receptors: proof with the competitive EP3 receptor antagonist L-826,266.
Q33485483Prostanoid receptor antagonists: development strategies and therapeutic applications
Q41984226Roles of affinity and lipophilicity in the slow kinetics of prostanoid receptor antagonists on isolated smooth muscle preparations
Q84020404The role of inflammation and COX-derived prostanoids in the effects of bradykinin on isolated rat aorta and urinary bladder

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